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2QPJ:
Human NEP complexed with a bifunctional NEP/DPP IV inhibitor
PDB ID:
2QPJ
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MMDB ID:
60922
PDB Deposition Date:
2007/7/24
Updated in MMDB:
2012/12
Experimental Method:
x-ray diffraction
Resolution:
2.05 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2QPJ: monomeric; determined by author
Molecular Components in 2QPJ
Label
Count
Molecule
Protein (1 molecule)
A
1
Neprilysin
(Gene symbol:
MME
)
Chemicals and Non-standard biopolymers (5 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
ZINC ION
3
1
(2S)-2-({(2S)-3-[(R)-[(1R)-1-({(4S)-4-amino-5-[(2S)-2-cyanopyrrolidin-1-yl]-5-oxopentanoyl}amino)ethyl](hydroxy)phosphoryl]-2-benzylpropanoyl}amino)propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303