2O22: Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand

PDB ID: 2O22Download
MMDB ID: 44640
PDB Deposition Date: 2006/11/29
Updated in MMDB: 2023/12
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Biological Unit for 2O22: monomeric; determined by author
Molecular Components in 2O22
Label Count Molecule
Protein (1 molecule)
1
Apoptosis Regulator Bcl-2
(Gene symbol: BCL2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamideN-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303