2IU0: crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

PDB ID: 2IU0Download
MMDB ID: 44538
PDB Deposition Date: 2006/5/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.53  Å
Source Organism:
Similar Structures:
Biological Unit for 2IU0: dimeric; determined by author and by software (PISA)
Molecular Components in 2IU0
Label Count Molecule
Proteins (2 molecules)
2
Bifunctional Purine Biosynthesis Protein Purh
(Gene symbol: ATIC)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
POTASSIUM IONPOTASSIUM ION
2
1
1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303