2IPJ: Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant Y24A in complex with NADP+ and epi-testosterone

PDB ID: 2IPJDownload
MMDB ID: 46916
PDB Deposition Date: 2006/10/12
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2IPJ: dimeric; determined by author
Molecular Components in 2IPJ
Label Count Molecule
Proteins (2 molecules)
2
Aldo-keto Reductase Family 1 Member C2
(Gene symbol: AKR1C2)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
3
SULFATE IONSULFATE ION
2
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
2
(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE
4
3
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
5
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303