2IPF: Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP+ and epi-testosterone

PDB ID: 2IPFDownload
MMDB ID: 46914
PDB Deposition Date: 2006/10/12
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 2IPF: dimeric; determined by author
Molecular Components in 2IPF
Label Count Molecule
Proteins (2 molecules)
2
(3(17)alpha-hydroxysteroid Dehydrogenase)
(Gene symbol: Akr1c21)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE
3
6
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303