2F29: Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor

PDB ID: 2F29Download
MMDB ID: 42729
PDB Deposition Date: 2005/11/15
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 2.921  Å
Source Organism:
Similar Structures:
Biological Unit for 2F29: monomeric; determined by author
Molecular Components in 2F29
Label Count Molecule
Protein (1 molecule)
1
Sialidase 2
(Gene symbol: NEU2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
2
3
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303