2F13: Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor

PDB ID: 2F13Download
MMDB ID: 42720
PDB Deposition Date: 2005/11/14
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 2.26  Å
Source Organism:
Similar Structures:
Biological Unit for 2F13: monomeric; determined by author
Molecular Components in 2F13
Label Count Molecule
Protein (1 molecule)
1
Sialidase 2
(Gene symbol: NEU2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PHOSPHATE IONPHOSPHATE ION
2
1
(2R)-2,3-dihydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid(2R)-2,3-dihydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303