2C5V: Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design

PDB ID: 2C5VDownload
MMDB ID: 86903
PDB Deposition Date: 2005/11/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2C5V: trimeric; determined by author and by software (PQS)
Molecular Components in 2C5V
Label Count Molecule
Proteins (3 molecules)
1
Cell Division Protein Kinase 2
Molecule annotation
1
Cyclin A2
Molecule annotation
1
Ala-ala-aba-arg-ser-leu-ile-pff-nh2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303