National Center for
Biotechnology Information

2C2Z: Crystal Structure Of Caspase-8 In Complex With Aza-peptide Michael Acceptor Inhibitor

PDB ID:

MMDB ID:

92258

PDB Deposition Date:

2005/10/2

Updated in MMDB:

2011/07

Experimental Method:

x-ray diffraction

Resolution:

1.95 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	C
Homo sapiens	A, B

Similar Structures:

Biological Unit for 2C2Z: hexameric; determined by author and by software (PQS)

Molecular Components in 2C2Z
Label	Count	Molecule
Proteins (6 molecules)
A A_1	2	Caspase-8 P18 Subunit
B B_1	2	Caspase-8 P10 Subunit
C C_1	2	Aza-peptide Inhibitor (5s, 8R, 11s)-8-(2-carboxyethyl) -14-[4-(3,4-dihydroquinolin-1(2h)-yl)-4-oxobutanoyl] -11-[(1r)-1-hydroxyethyl]-5-(2-methylpropyl)-3,6,9,12-tetraoxo -1-phenyl-2-oxa-4,7,10,13,14-pentaazahexadecan-16-oic Acid
Chemicals and Non-standard biopolymers (2 molecules)
1	2	Dithiane Diol

* Click molecule labels to explore molecular sequence information.

Citing MMDB