2B1I: crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

PDB ID: 2B1IDownload
MMDB ID: 42555
PDB Deposition Date: 2005/9/15
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 2.02  Å
Source Organism:
Similar Structures:
Biological Unit for 2B1I: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 2B1I
Label Count Molecule
Proteins (2 molecules)
2
Bifunctional Purine Biosynthesis Protein Purh
(Gene symbol: ATIC)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
POTASSIUM IONPOTASSIUM ION
2
4
[3,4-DIHYDROXY-5R-(2,2,4-TRIOXO-1,2R,3S,4R-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-7-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE[3,4-DIHYDROXY-5R-(2,2,4-TRIOXO-1,2R,3S,4R-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-7-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303