1S1P: Crystal structures of prostaglandin D2 11-ketoreductase (AKR1C3) in complex with the non-steroidal anti-inflammatory drugs flufenamic acid and indomethacin

PDB ID: 1S1PDownload
MMDB ID: 26977
PDB Deposition Date: 2004/1/7
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1S1P: monomeric; determined by author
Molecular Components in 1S1P
Label Count Molecule
Protein (1 molecule)
1
Aldo-keto Reductase Family 1 Member C3
(Gene symbol: AKR1C3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ACETATE IONACETATE ION
2
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
1
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303