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1HSH:
CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
PDB ID:
1HSH
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MMDB ID:
4291
PDB Deposition Date:
1995/3/31
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Human immunodeficiency virus type 2 (ISOLATE ROD)
Similar Structures:
VAST+
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Biological Unit for 1HSH: dimeric; determined by author and by software (PISA)
Molecular Components in 1HSH
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Hiv-ii Protease
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303