1H3C: Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme

PDB ID: 1H3CDownload
MMDB ID: 24059
PDB Deposition Date: 2002/8/25
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 1H3C: dimeric; determined by author and by software (PQS)
Molecular Components in 1H3C
Label Count Molecule
Proteins (2 molecules)
2
Squalene--hopene Cyclase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
2
2
N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINEN-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303