NCBI
National Center for
Biotechnology Information
Search
1DIB:
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899
PDB ID:
1DIB
Download
MMDB ID:
13545
PDB Deposition Date:
1999/11/29
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1DIB: dimeric; determined by author and by software (PISA)
Molecular Components in 1DIB
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Methylenetetrahydrofolate Dehydrogenase/cyclohydrolase
(Gene symbol:
MTHFD1
)
Chemicals and Non-standard biopolymers (3 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMI C ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303