|
| Status |
Public on Jul 14, 2017 |
| Title |
Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-seq transcriptome analysis identified an early requirement for zic2 in periocular neural crest as an activator of alx1, a transcription factor with essential roles in craniofacial and ocular morphogenesis in human and zebrafish
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| |
|
| Overall design |
Embryos derived from a zic2aGBT133/+; zic2bUW1127/+ incross were sorted by presence or absence of coloboma. RNA was prepared from each individual embryo at ~ 25 hpf
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| |
|
| Contributor(s) |
Sedykh I, Yoon B, Robertson L, Moskvin O, Dewey C, Grinblat Y |
| Citation(s) |
28689736 |
| |
| Submission date |
May 29, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Oleg Moskvin |
| Organization name |
University of Wisconsin-Madison
|
| Street address |
1220 Capitol Court
|
| City |
Madison |
| State/province |
WI |
| ZIP/Postal code |
53715 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18413 |
Illumina HiSeq 2500 (Danio rerio) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA388340 |
| SRA |
SRP108221 |
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