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| Status |
Public on Sep 01, 2008 |
| Title |
Gene expression profiling of N-CoR2 overexpression in response to death induction |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The series represent gene expression profiles of T4-2 neoplastic breast epithelial cells that overexpressed N-CoR2 and were treated with the death ligand TRAIL in three-dimensional reconstituted basement membrane culture.
Keywords: Genetic modification; response to death induction
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| Overall design |
Four replicate cultures were established for each of the 4 experiment groups, including those using T4-2 cells that stably expressed N-CoR2 (T4-2_NCOR2), T4-2 cells expressing the empty vector (T4-2_vector), TRAIL-treated T4-2 N-CoR2 cells (T4-2_NCOR2_TRAIL), and TRAIL-treated T4-2 vector cells (T4-2_vector_TRAIL). Cells were grown on top of reconstituted basement membrane for 6 days and then treated with TRAIL (1 μg/mL) or vehicles for 4 hours before the collection of RNA samples.
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| Contributor(s) |
Tsai KK, Weaver VM, Chatterjee C, Lakins JN, Nuth M, Tobias JW, Mian IS |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 02, 2007 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Kelvin Kun-Chih Tsai |
| E-mail(s) |
kkctsai@gmail.com
|
| Organization name |
University of California, San Francisco
|
| Department |
Surgery
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| Lab |
Valerie M. Weaver
|
| Street address |
513 Parnassus Avenue, Rm S1364
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94143 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA101355 |
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