|
| Status |
Public on Jan 27, 2016 |
| Title |
Synovial biopsies of rheumatoid arthritis and healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Synovial biopsies were obtained from rheumatoid arthritis (RA) synovium and from subjects without a joint disease to find gene upregulated during RA.
The promoters of genes upregulated during RA compared to HC can be used to obtain disease-regulated gene therapy.
|
| |
|
| Overall design |
16 microarrays of end-stage RA synovial biopsies were compared to 7 microarrays of synovial biopsies from individuals without a joint disease. Genes with >1.2-fold upregulation and P<0.05 in RA VS HC were selected from the analysis.
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| |
|
| Contributor(s) |
Broeren MG |
| Citation(s) |
26711533 |
| |
| Submission date |
Jan 27, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Mathijs G.A. Broeren |
| E-mail(s) |
mathijs.broeren@radboudumc.nl
|
| Organization name |
Radboud university medical Center
|
| Department |
Department of Rheumatology
|
| Lab |
Experimental Rheumatology
|
| Street address |
Geert Grootplein 28
|
| City |
Nijmegen |
| ZIP/Postal code |
6525GA |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (23)
|
|
| Relations |
| BioProject |
PRJNA309988 |
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