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Series GSE50878 Query DataSets for GSE50878
Status Public on Feb 20, 2014
Title SM007 - Infection with SARS MA15 of C57BL6/J mice and CXCR3 knockouts in the same strain of mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The purpose of this experiment is to compare the host response of C57BL6/J mice to that of CXCR3 knockout mutant mice in response to SARS MA15 virus infections.
 
Overall design Groups of 10 week old C57BL6 mice or CXCR3 knockout mice were infected with SARS MA15 at a dose of 10^5 PFU or mock infected. Mice were euthanized on days 2, 4 and 7 post infection to measure virus load and isolate samples for measurement of virus load, lung pathology, and transcriptional. Mock infected animals were also harvested at each time point. Mice were weighed every 24 hours to measure general disease progression and any mouse approaching 30% weight loss were euthanized.
 
Contributor(s) Baric R, Katze M, Gralinski L, Chang J, Law L
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Sep 15, 2013
Last update date Jan 12, 2017
Contact name Michael Katze
E-mail(s) data@viromics.washington.edu
Organization name University of Washington
Department Microbiology
Lab Michael G. Katze, Ph.D
Street address Rosen Building 960 Republican St.
City Seattle
State/province WA
ZIP/Postal code 98109-4325
Country USA
 
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (33)
GSM1231651 SM007_B6_MA15_d2_1
GSM1231652 SM007_B6_MA15_d2_2
GSM1231653 SM007_B6_MA15_d2_3
Relations
BioProject PRJNA219234

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50878_RAW.tar 288.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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