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Status |
Public on Jun 17, 2011 |
Title |
Exon array analysis in primary human fibroblasts |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Exon usage analysis in in vitro cultured fibroblast cells. To assay the genome-wide splicing changes during cellular senescence, we performed splicing analysis on young and old normal fibroblasts, and in fibroblasts +/- tert (telomerase protein subunit Tert immortalized).
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Overall design |
We analyzed primary fibroblasts from 5 healthy subjects at various passages and from 2 Hutchinson-Gilford Progeria Syndrome (HGPS) patients using the Affymetrix Human Exon 1.0 ST platform. Two or three technical replicates were performed.
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Contributor(s) |
Kan C, Collins F |
Citation(s) |
21670498 |
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Submission date |
Apr 26, 2011 |
Last update date |
Feb 18, 2019 |
Contact name |
Kan Cao |
E-mail(s) |
kcao@umd.edu
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Organization name |
University of Maryland
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Department |
CBMG
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Street address |
2219 Bioscience Research building
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City |
College Park |
ZIP/Postal code |
20742 |
Country |
USA |
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Platforms (2) |
GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
GPL5188 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
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Samples (34)
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Relations |
BioProject |
PRJNA140579 |