|
| Status |
Public on Nov 25, 2020 |
| Title |
RNAseq analysis of MM13 and MM2 metastatic melanoma PDX cells overexpressing TINCR |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: Study the changes in cell transcriptome upon overexpression of lncRNA TINCR
Methods: Primary melanoma cell line WM902B was transduced with lientiviruses expressing Scrambled and TINCR directed shRNA hairpins
Results: we found that TINCR overexpression induces partial reversion of invasive phenotype
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| |
|
| Overall design |
Analysis of differential gene expression in control and TINCR overexpressing MM2 and MM13 metastsatic melanoma PDX cells
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| |
|
| Contributor(s) |
Melixetian M, Bossi D, Mihalovich M, Punzi S, Barozzi I, Testa G, Cuomo A, Bonaldi T, Leucci E, Marine J, Minucci S, Pelicci PG, Lanfrancone L |
| Citation(s) |
33586907 |
| |
| Submission date |
Jan 29, 2019 |
| Last update date |
Feb 26, 2021 |
| Contact name |
Marine Melixetian |
| E-mail(s) |
marine.melixetian@ieo.eu
|
| Organization name |
European Institute of Oncology
|
| Street address |
via Adamello 16
|
| City |
Milano |
| ZIP/Postal code |
20141 |
| Country |
Italy |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (8)
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|
| This SubSeries is part of SuperSeries: |
| GSE125835 |
Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation |
|
| Relations |
| BioProject |
PRJNA517676 |
| SRA |
SRP182819 |
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