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| Status |
Public on Jul 07, 2019 |
| Title |
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Gemcitabine resistance is currently the main problem of chemotherapy for advanced pancreatic cancer patients. The resistance is thought to be caused by altered drug metabolism or reduced apoptosis of cancer cells. However, the underlying mechanism of Gemcitabine resistance in pancreatic cancer remains unclear. In this study, we established Gemcitabine resistant PANC-1 (PANC-1-GR) cell lines and compared the circular RNAs (circRNAs) profiles between PANC-1 cells and PANC-1-GR cells by RNA sequencing.
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| |
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| Overall design |
Examing 2 conditions, each with 3 replicates
|
| |
|
| Contributor(s) |
Huang M, Shao F |
| Citation(s) |
29922161 |
| |
| Submission date |
Feb 13, 2018 |
| Last update date |
Feb 07, 2020 |
| Contact name |
Mei Huang |
| E-mail(s) |
75352483@qq.com
|
| Organization name |
Anhui Provincial Hospital
|
| Department |
General surgery
|
| Lab |
Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery
|
| Street address |
17#Lu Jiang Road
|
| City |
HeFei |
| State/province |
An Hui |
| ZIP/Postal code |
230001 |
| Country |
China |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA434013 |
| SRA |
SRP132822 |
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