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mntb MAX network transcriptional repressor b [ Danio rerio (zebrafish) ]

Gene ID: 556663, updated on 2-Nov-2024

Summary

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Official Symbol
mntbprovided by ZNC
Official Full Name
MAX network transcriptional repressor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070820-8
See related
Ensembl:ENSDARG00000073988 AllianceGenome:ZFIN:ZDB-GENE-070820-8
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Mnt; zgc:165490
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human MNT (MAX network transcriptional repressor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See mntb in Genome Data Viewer
Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (39462519..39512495)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (39417438..39465797)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene clustered mitochondria protein homolog Neighboring gene platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b Neighboring gene septin 4a Neighboring gene dynein, light chain, LC8-type 2b Neighboring gene serine and arginine rich splicing factor 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish. Hu P, et al. Sci Rep, 2016 Jun 30. PMID 27356472, Free PMC Article
  2. Early depletion of primordial germ cells in zebrafish promotes testis formation. Tzung KW, et al. Stem Cell Reports, 2015 Jan 13. PMID 25434820, Free PMC Article
  3. Phylogenetic analysis of zebrafish basic helix-loop-helix transcription factors. Wang Y, et al. J Mol Evol, 2009 Jun. PMID 19449054
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MAX network transcriptional repressor b
Names
MAX binding protein b
Mnt1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103111.1 → NP_001096581.1  MAX network transcriptional repressor b

    See identical proteins and their annotated locations for NP_001096581.1

    Status: PROVISIONAL

    Source sequence(s)
    BC150227
    UniProtKB/TrEMBL
    A7E277
    Related
    ENSDARP00000098909.1, ENSDART00000114825.3
    Conserved Domains (2) summary
    cd14686
    Location:272 → 313
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam00010
    Location:231 → 281
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    39462519..39512495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170271.5 → XP_005170328.1  MAX network transcriptional repressor b isoform X1

    UniProtKB/TrEMBL
    A0A8M2BI31, E7FCB9
    Related
    ENSDARP00000109832.1, ENSDART00000123970.3
    Conserved Domains (2) summary
    cd14686
    Location:292 → 333
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam00010
    Location:251 → 301
    HLH; Helix-loop-helix DNA-binding domain
Nucleotide Protein
Heading Accession and Version

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