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myog.L myogenin L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 378648, updated on 4-Nov-2024

Summary

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Official Symbol
myog.L
Official Full Name
myogenin L homeolog
Primary source
Xenbase:XB-GENE-6252382
Locus tag
XELAEV_18012441mg
See related
EnsemblRapid:ENSXLAG00005002398 AllianceGenome:Xenbase:XB-GENE-6252382
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
myf4; Xmyog; myf-4; myog-a; myog-b; XmyogU1; myogU1-A; myogenin; XMyogenin
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to act upstream of or within positive regulation of cell differentiation; positive regulation of transcription by RNA polymerase II; and skeletal muscle cell differentiation. Predicted to be located in nucleus. Is expressed in mesenchyme; mesoderm; musculoskeletal system; and pharyngeal arch. Orthologous to human MYOG (myogenin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See myog.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (84340857..84350726, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (78770020..78779918, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene ras and Rab interactor 3-like Neighboring gene transmembrane protein 183A L homeolog Neighboring gene adenosine A1 receptor L homeolog Neighboring gene parathyroid hormone-related protein-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two myogenin-related genes are differentially expressed in Xenopus laevis myogenesis and differ in their ability to transactivate muscle structural genes. Charbonnier F, et al. J Biol Chem, 2002 Jan 11. PMID 11684685

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within muscle organ development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of myoblast differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of skeletal muscle fiber development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
myogenin L homeolog
Names
myf 4
myogenin (myogenic factor 4) L homeolog
myogenin U1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085857.1 → NP_001079326.1  myogenin L homeolog

    See identical proteins and their annotated locations for NP_001079326.1

    Status: PROVISIONAL

    Source sequence(s)
    AY046531
    UniProtKB/TrEMBL
    A0A974DIJ7, A0A974DPH0, Q8UUX8
    Related
    ENSXLAP00005007183.1, ENSXLAT00005007292.1
    Conserved Domains (2) summary
    smart00520
    Location:1 → 96
    BASIC; Basic domain in HLH proteins of MYOD family
    pfam00010
    Location:92 → 143
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    84340857..84350726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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