GEO DataSets

(Submitter supplied) Approximately 15% of US adults have circulating levels of uric acid above its solubility limit, which is causally linked to the inflammatory disease gout. In most mammals, uric acid elimination is facilitated by the enzyme uricase. However, human uricase is a pseudogene, having been inactivated early in hominid evolution. Though it has long been known that a substantial amount of uric acid is eliminated in the gut, the role of the gut microbiota in hyperuricemia has not been studied. more...

Organism:

[Clostridium] saccharolyticum WM1; Collinsella aerofaciens ATCC 25986; Clostridium sporogenes ATCC 15579

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL32367 GPL32368 GPL32369

18 Samples

Download data: TXT

(Submitter supplied) The members of the genus Clostridium, such as the other spore-forming anaerobic bacteria, have a complex and strictly regulated life-cycle but very little is known about genetic pathways involved at different stages. Clostridium sporogenes, Gram positive bacterium usually involved in food spoilage and frequently isolated from late blowed cheese is genetically indistinguishable from proteolytic Clostridium botulinum and is the non-neurotoxigenic counterpart often used as exemplar for the toxic subtypes. more...

Organism:

Clostridium sporogenes; Clostridium botulinum A str. ATCC 3502

Type:

Expression profiling by array

Platform:

GPL15677

12 Samples

Download data: TXT

(Submitter supplied) Strains were differentiated on the basis of hybridization to probes representing strain variable regions in C. botulinum strain ATCC 3502. Probes for selected genes (eg. toxin genes) were also featured on the microarray to allow detection of other serotypes/subtypes.

Organism:

Clostridium perfringens; Clostridium argentinense; Clostridium butyricum; Clostridium botulinum; Clostridium sporogenes; Clostridium baratii; Clostridium botulinum A str. ATCC 3502

Type:

Genome variation profiling by array

Platform:

GPL8538

44 Samples

Download data: TXT