| ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFbetaR1 ISGylation. | ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation.
Cui N, Liu C, Tang X, Song L, Xiao Z, Wang C, Wu Y, Zhou Y, Peng C, Liu Y, Zheng L, Liu X, Huang K, Chen H., Free PMC Article | 08/9/2024 |
| Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage. | Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage.
Homma H, Yoshioka Y, Fujita K, Shirai S, Hama Y, Komano H, Saito Y, Yabe I, Okano H, Sasaki H, Tanaka H, Okazawa H., Free PMC Article | 04/24/2024 |
| ISG15 Promotes Progression and Gemcitabine Resistance of Pancreatic Cancer Cells Through ATG7. | ISG15 Promotes Progression and Gemcitabine Resistance of Pancreatic Cancer Cells Through ATG7.
Meng Y, Bian L, Zhang M, Zhou P, Zhang S, Ying Y, Yang S, Liu Y, Yao Y, Li D., Free PMC Article | 02/26/2024 |
| Evaluation of long non-coding RNAs EGOT, NRAV, NRIR and mRNAs ISG15 and IFITM3 expressions in COVID-19 patients. | Evaluation of long non-coding RNAs EGOT, NRAV, NRIR and mRNAs ISG15 and IFITM3 expressions in COVID-19 patients.
Sefatjoo Z, Mohebbi SR, Hosseini SM, Shoraka S, Saeedi Niasar M, Baghaei K, Meyfour A, Sadeghi A, Malekpour H, Asadzadeh Aghdaei H, Zali MR. | 02/4/2024 |
| ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-gamma Secretion from CD8+ T Cells in Vitiligo. | ISG15-USP18 Dysregulation by Oxidative Stress Promotes IFN-γ Secretion from CD8+ T Cells in Vitiligo.
Lee EJ, Kim JY, Yeo JH, Park S, Bae YJ, Kwon IJ, Seong SH, Lee J, Oh SH. | 01/27/2024 |
| Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition. | Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition.
Burleigh A, Moraitis E, Al Masroori E, Al-Abadi E, Hong Y, Omoyinmi E, Titheradge H, Stals K, Jones WD, Gait A, Jayarajan V, Di WL, Sebire N, Solman L, Ogboli M, Welch SB, Sudarsanam A, Wacogne I, Price-Kuehne F, Jensen B, Brogan PA, Eleftheriou D., Free PMC Article | 12/29/2023 |
| A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia. | A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia.
Xu Q, Li W, Zhao Q, Zhao L, Lv G, Sun G, Gao Y, Ding Y, Zhang Z, Zhou L, Chen Y, Tang X, Zhu J, Zhao X, An Y. | 12/21/2023 |
| ISG15: its roles in SARS-CoV-2 and other viral infections. | ISG15: its roles in SARS-CoV-2 and other viral infections.
Sarkar L, Liu G, Gack MU., Free PMC Article | 11/16/2023 |
| ISG15 and ISGylation modulates cancer stem cell-like characteristics in promoting tumor growth of anaplastic thyroid carcinoma. | ISG15 and ISGylation modulates cancer stem cell-like characteristics in promoting tumor growth of anaplastic thyroid carcinoma.
Xu T, Zhu C, Chen J, Song F, Ren X, Wang S, Yi X, Zhang Y, Zhang W, Hu Q, Qin H, Liu Y, Zhang S, Tan Z, Pan Z, Huang P, Ge M., Free PMC Article | 08/2/2023 |
| The role of interferon-stimulated gene 15 in the occurence and progression of cervical squamous cell carcinoma. | The role of interferon-stimulated gene 15 in the occurence and progression of cervical squamous cell carcinoma.
Zhao W, Liu YK, Li DJ, Zhao XW, Deng HY, Du NY. | 05/30/2023 |
| Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Wydorski PM, Osipiuk J, Lanham BT, Tesar C, Endres M, Engle E, Jedrzejczak R, Mullapudi V, Michalska K, Fidelis K, Fushman D, Joachimiak A, Joachimiak LA., Free PMC Article | 05/24/2023 |
| Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus. | Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus.
Liu SY, Huang M, Fung TS, Chen RA, Liu DX., Free PMC Article | 05/8/2023 |
| Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure. | Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure.
Yerra VG, Batchu SN, Kaur H, Kabir MDG, Liu Y, Advani SL, Tran DT, Sadeghian S, Sedrak P, Billia F, Kuzmanov U, Gramolini AO, Qasrawi DO, Petrotchenko EV, Borchers CH, Connelly KA, Advani A., Free PMC Article | 05/3/2023 |
| Interferon stimulated gene 15 (ISG15) in cancer: An update. | Interferon stimulated gene 15 (ISG15) in cancer: An update.
Nguyen HM, Gaikwad S, Oladejo M, Agrawal MY, Srivastava SK, Wood LM. | 02/23/2023 |
| The Functional Roles of ISG15/ISGylation in Cancer. | The Functional Roles of ISG15/ISGylation in Cancer.
Yuan Y, Qin H, Li H, Shi W, Bao L, Xu S, Yin J, Zheng L., Free PMC Article | 02/14/2023 |
| ISGylation directly modifies hypoxia-inducible factor-2alpha and enhances its polysome association. | ISGylation directly modifies hypoxia-inducible factor-2α and enhances its polysome association.
Melanson G, Du Bois AC, Webster C, Uniacke J. | 11/19/2022 |
| ISG15 enhances glioma cell stemness by promoting Oct4 protein stability. | ISG15 enhances glioma cell stemness by promoting Oct4 protein stability.
Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H. | 08/13/2022 |
| Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection. | Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection.
Tecalco Cruz AC. | 07/23/2022 |
| Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification. | Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification.
Lyu F, Li Y, Yan Z, He Q, Cheng L, Zhang P, Liu B, Liu C, Song Y, Xing Y., Free PMC Article | 05/14/2022 |
| Interferonstimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response. | Interferon‑stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response.
Zhao X, Wang J, Wang Y, Zhang M, Zhao W, Zhang H, Zhao L., Free PMC Article | 04/30/2022 |
| ISG15 deficiency restricts HIV-1 infection. | ISG15 deficiency restricts HIV-1 infection.
Jurczyszak D, Manganaro L, Buta S, Gruber C, Martin-Fernandez M, Taft J, Patel RS, Cipolla M, Alshammary H, Mulder LCF, Sachidanandam R, Bogunovic D, Simon V., Free PMC Article | 04/23/2022 |
| ISG15 and ISGylation in Human Diseases. | ISG15 and ISGylation in Human Diseases.
Mirzalieva O, Juncker M, Schwartzenburg J, Desai S., Free PMC Article | 04/16/2022 |
| Congenital deficiency reveals critical role of ISG15 in skin homeostasis. | Congenital deficiency reveals critical role of ISG15 in skin homeostasis.
Malik MNH, Waqas SF, Zeitvogel J, Cheng J, Geffers R, Gouda ZA, Elsaman AM, Radwan AR, Schefzyk M, Braubach P, Auber B, Olmer R, Müsken M, Roesner LM, Gerold G, Schuchardt S, Merkert S, Martin U, Meissner F, Werfel T, Pessler F., Free PMC Article | 04/2/2022 |
| Roles of ESCRT Proteins ALIX and CHMP4A and Their Interplay with Interferon-Stimulated Gene 15 during Tick-Borne Flavivirus Infection. | Roles of ESCRT Proteins ALIX and CHMP4A and Their Interplay with Interferon-Stimulated Gene 15 during Tick-Borne Flavivirus Infection.
Tran PT, Chiramel AI, Johansson M, Melik W., Free PMC Article | 03/5/2022 |
| Unraveling the Molecular Mechanism of Recognition of Human Interferon-Stimulated Gene Product 15 by Coronavirus Papain-Like Proteases: A Multiscale Simulation Study. | Unraveling the Molecular Mechanism of Recognition of Human Interferon-Stimulated Gene Product 15 by Coronavirus Papain-Like Proteases: A Multiscale Simulation Study.
Roy R, Jonniya NA, Poddar S, Sk MF, Kar P. | 01/8/2022 |