| High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population. | High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population.
Pavlova NI, Krylov AV, Bochurov AA, Alekseev VA, Kurtanov KA. | 09/20/2024 |
| FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer. | FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.
Lorito N, Subbiani A, Smiriglia A, Bacci M, Bonechi F, Tronci L, Romano E, Corrado A, Longo DL, Iozzo M, Ippolito L, Comito G, Giannoni E, Meattini I, Avgustinova A, Chiarugi P, Bachi A, Morandi A., Free PMC Article | 08/13/2024 |
| FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response. | FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response.
Ikeda T, Katoh Y, Hino H, Seta D, Ogawa T, Iwata T, Nishio H, Sugawara M, Hirai S., Free PMC Article | 06/17/2024 |
| Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study. | Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study.
Miklavcic JJ, Paterson N, Hahn-Holbrook J, Glynn L. | 05/23/2024 |
| Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function. | Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function.
Wu X, Jiang L, Qi H, Hu C, Jia X, Lin H, Wang S, Lin L, Zhang Y, Zheng R, Li M, Wang T, Zhao Z, Xu M, Xu Y, Chen Y, Zheng J, Bi Y, Lu J., Free PMC Article | 03/8/2024 |
| Hsa_circ_0000073 promotes lipid synthesis of osteosarcoma through hsa-miR-1184/ FADS2 pathway. | Hsa_circ_0000073 promotes lipid synthesis of osteosarcoma through hsa-miR-1184/ FADS2 pathway.
Ren Z, Wang S, Li B, Huang H, Zhang H, Yang Z, Tian X. | 09/1/2023 |
| Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. | Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.
Mathieson I, Day FR, Barban N, Tropf FC, Brazel DM, eQTLGen Consortium, BIOS Consortium, Vaez A, van Zuydam N, Bitarello BD, Gardner EJ, Akimova ET, Azad A, Bergmann S, Bielak LF, Boomsma DI, Bosak K, Brumat M, Buring JE, Cesarini D, Chasman DI, Chavarro JE, Cocca M, Concas MP, Davey Smith G, Davies G, Deary IJ, Esko T, Faul JD, FinnGen Study, Franco O, Ganna A, Gaskins AJ, Gelemanovic A, de Geus EJC, Gieger C, Girotto G, Gopinath B, Grabe HJ, Gunderson EP, Hayward C, He C, van Heemst D, Hill WD, Hoffmann ER, Homuth G, Hottenga JJ, Huang H, Hyppӧnen E, Ikram MA, Jansen R, Johannesson M, Kamali Z, Kardia SLR, Kavousi M, Kifley A, Kiiskinen T, Kraft P, Kühnel B, Langenberg C, Liew G, Lifelines Cohort Study, Lind PA, Luan J, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Mbarek H, McCarthy MI, McMahon G, Medland SE, Meitinger T, Metspalu A, Mihailov E, Milani L, Missmer SA, Mitchell P, Møllegaard S, Mook-Kanamori DO, Morgan A, van der Most PJ, de Mutsert R, Nauck M, Nolte IM, Noordam R, Penninx BWJH, Peters A, Peyser PA, Polašek O, Power C, Pribisalic A, Redmond P, Rich-Edwards JW, Ridker PM, Rietveld CA, Ring SM, Rose LM, Rueedi R, Shukla V, Smith JA, Stankovic S, Stefánsson K, Stöckl D, Strauch K, Swertz MA, Teumer A, Thorleifsson G, Thorsteinsdottir U, Thurik AR, Timpson NJ, Turman C, Uitterlinden AG, Waldenberger M, Wareham NJ, Weir DR, Willemsen G, Zhao JH, Zhao W, Zhao Y, Snieder H, den Hoed M, Ong KK, Mills MC, Perry JRB. | 05/25/2023 |
| Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies. | Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies.
Bobiński R, Mazurek U, Zmarzly N, Ulman-Włodarz I, Dutka M, Pizon M, Pollok-Waksmańska W, Pielesz A, Hajduga M, Zimmer K, Bujok J, Pająk C, Ilczak T. | 03/21/2023 |
| The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes. | The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes.
Chen E, Wang C, Lv H, Yu J., Free PMC Article | 02/16/2023 |
| The integrative panel of fatty acid desaturase-2 (FADS2) rs174583 gene polymorphism and dietary indices (DQI-I and HEI) affects cardiovascular risk factors among obese individuals. | The integrative panel of fatty acid desaturase-2 (FADS2) rs174583 gene polymorphism and dietary indices (DQI-I and HEI) affects cardiovascular risk factors among obese individuals.
Mahmoudinezhad M, Khosravaniardakani S, Saljoughi Badelou L, Fayyazishishavan E, Kahroba H, Farhangi MA., Free PMC Article | 02/16/2023 |
| NSCLC Cells Resistance to PI3K/mTOR Inhibitors Is Mediated by Delta-6 Fatty Acid Desaturase (FADS2). | NSCLC Cells Resistance to PI3K/mTOR Inhibitors Is Mediated by Delta-6 Fatty Acid Desaturase (FADS2).
Colombo M, Passarelli F, Corsetto PA, Rizzo AM, Marabese M, De Simone G, Pastorelli R, Broggini M, Brunelli L, Caiola E., Free PMC Article | 12/31/2022 |
| Association of placental fatty acid desaturase 2 (FADS2) methylation with maternal fatty acid levels in women with preeclampsia. | Association of placental fatty acid desaturase 2 (FADS2) methylation with maternal fatty acid levels in women with preeclampsia.
Dave K, Kaur L, Sundrani D, Sharma P, Bayyana S, Mehendale S, Randhir K, Chandak GR, Joshi S. | 09/24/2022 |
| Interplay between fatty acid desaturase2 (FADS2) rs174583 genetic variant and dietary antioxidant capacity: cardio-metabolic risk factors in obese individuals. | Interplay between fatty acid desaturase2 (FADS2) rs174583 genetic variant and dietary antioxidant capacity: cardio-metabolic risk factors in obese individuals.
Khodarahmi M, Javidzade P, Farhangi MA, Hashemzehi A, Kahroba H., Free PMC Article | 07/16/2022 |
| Interaction analysis of FADS2 gene variants with chronic hepatitis B infection in Chinese patients. | Interaction analysis of FADS2 gene variants with chronic hepatitis B infection in Chinese patients.
Sun YH, Gao J, Shi JH, Cao SL, Yan ZP, Liu XD, Zhang HP, Li J, Guo WZ, Zhang SJ. | 06/11/2022 |
| SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells. | SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells.
Xuan Y, Wang H, Yung MM, Chen F, Chan WS, Chan YS, Tsui SK, Ngan HY, Chan KK, Chan DW., Free PMC Article | 05/28/2022 |
| Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation. | Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation.
Pararasa C, Messenger DJ, Barrett KE, Hyliands D, Talbot D, Fowler MI, Kawatra T, Gunn DA, Lim FL, Wainwright LJ, Jenkins G, Griffiths HR., Free PMC Article | 04/23/2022 |
| FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study. | FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study.
Santana JDM, Pereira M, Carvalho GQ, Gouveia Peluzio MDC, Drumond Louro I, Santos DBD, Oliveira AM., Free PMC Article | 03/19/2022 |
| Characterization of a novel FADS2 transcript variant: implications for D6D activity regulation in cells. | Characterization of a novel FADS2 transcript variant: implications for D6D activity regulation in cells.
Marks KA, Fernandes MF, Diaguarachchige De Silva KH, Tomczewski MV, Stark KD, Duncan RE. | 01/22/2022 |
| Apocryphal FADS2 activity promotes fatty acid diversification in cancer. | Apocryphal FADS2 activity promotes fatty acid diversification in cancer.
Young RSE, Bowman AP, Williams ED, Tousignant KD, Bidgood CL, Narreddula VR, Gupta R, Marshall DL, Poad BLJ, Nelson CC, Ellis SR, Heeren RMA, Sadowski MC, Blanksby SJ. | 01/22/2022 |
| Influence of genetic variants in FADS2 and ELOVL2 genes on BMI and PUFAs homeostasis in children and adolescents with obesity. | Influence of genetic variants in FADS2 and ELOVL2 genes on BMI and PUFAs homeostasis in children and adolescents with obesity.
Maguolo A, Zusi C, Giontella A, Miraglia Del Giudice E, Tagetti A, Fava C, Morandi A, Maffeis C. | 12/25/2021 |
| Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants. | Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants.
Matsumoto A, Kawabata T, Kagawa Y, Shoji K, Kimura F, Miyazawa T, Tatsuta N, Arima T, Yaegashi N, Nakai K. | 12/4/2021 |
| Fatty acid desaturase 2 (FADS 2) rs174575 (C/G) polymorphism, circulating lipid levels and susceptibility to type-2 diabetes mellitus. | Fatty acid desaturase 2 (FADS 2) rs174575 (C/G) polymorphism, circulating lipid levels and susceptibility to type-2 diabetes mellitus.
Shetty SS, Kumari NS., Free PMC Article | 11/6/2021 |
| Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility. | Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility.
Langer-Gould A, Black LJ, Waubant E, Smith JB, Wu J, Gonzales EG, Shao X, Koebnick C, Lucas RM, Xiang A, Barcellos LF., Free PMC Article | 10/2/2021 |
| FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study. | FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study.
Zec MM, Stojković L, Zeković M, Pokimica B, Zivkovic M, Stankovic A, Glibetic M. | 10/2/2021 |
| Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. | Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality.
Thomas T, Cendali F, Fu X, Gamboni F, Morrison EJ, Beirne J, Nemkov T, Antonelou MH, Kriebardis A, Welsby I, Hay A, Dziewulska KH, Busch MP, Kleinman S, Buehler PW, Spitalnik SL, Zimring JC, D'Alessandro A., Free PMC Article | 07/24/2021 |