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    SLC25A51 solute carrier family 25 member 51 [ Homo sapiens (human) ]

    Gene ID: 92014, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    SLC25A51 decouples the mitochondrial NAD[+]/NADH ratio to control proliferation of AML cells.

    SLC25A51 decouples the mitochondrial NAD(+)/NADH ratio to control proliferation of AML cells.
    Lu MJ, Busquets J, Impedovo V, Wilson CN, Chan HR, Chang YT, Matsui W, Tiziani S, Cambronne XA.,

    04/10/2024
    Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51.

    Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51.
    Goyal S, Cambronne XA., Free PMC Article

    12/28/2023
    Dynamics of SLC25A51 reveal preference for oxidized NAD[+] and substrate led transport.

    Dynamics of SLC25A51 reveal preference for oxidized NAD(+) and substrate led transport.
    Goyal S, Paspureddi A, Lu MJ, Chan HR, Lyons SN, Wilson CN, Niere M, Ziegler M, Cambronne XA., Free PMC Article

    10/11/2023
    Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.

    Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.
    Güldenpfennig A, Hopp AK, Muskalla L, Manetsch P, Raith F, Hellweg L, Dördelmann C, Leslie Pedrioli DM, Johnsson K, Superti-Furga G, Hottiger MO., Free PMC Article

    09/28/2023
    SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis.

    SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis.
    Li Y, Bie J, Zhao L, Song C, Zhang T, Li M, Yang C, Luo J., Free PMC Article

    08/10/2023
    Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis.

    Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis.
    Gupta N, Sahar T, Khowal S, Ganaie IA, Mughees M, Khullar D, Jain SK, Wajid S.

    01/8/2022
    Welcome to the Family: Identification of the NAD(+) Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25.

    Welcome to the Family: Identification of the NAD(+) Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25.
    Ziegler M, Monné M, Nikiforov A, Agrimi G, Heiland I, Palmieri F., Free PMC Article

    09/25/2021
    SLC25A51 is a mammalian mitochondrial NAD(+) transporter.

    SLC25A51 is a mammalian mitochondrial NAD(+) transporter.
    Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA., Free PMC Article

    02/6/2021
    Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import.

    Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import.
    Girardi E, Agrimi G, Goldmann U, Fiume G, Lindinger S, Sedlyarov V, Srndic I, Gürtl B, Agerer B, Kartnig F, Scarcia P, Di Noia MA, Liñeiro E, Rebsamen M, Wiedmer T, Bergthaler A, Palmieri L, Superti-Furga G., Free PMC Article

    12/19/2020
    Compares and contrasts all the known human SLC25A* genes and includes functional information.

    The mitochondrial transporter family SLC25: identification, properties and physiopathology.
    Palmieri F.

    07/2/2013
    Observational study of gene-disease association. (HuGE Navigator)

    Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article

    12/5/2010
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