| Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet beta-cell function in health and metabolic stress: Is there room for MALT1? | Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?
Kowluru A., Free PMC Article | 12/6/2023 |
| A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification. | A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification.
Plaisance I, Chouvardas P, Sun Y, Nemir M, Aghagolzadeh P, Aminfar F, Shen S, Shim WJ, Rochais F, Johnson R, Palpant N, Pedrazzini T., Free PMC Article | 06/22/2023 |
| BCL10 correlates with bad prognosis and immune infiltration of tumor microenvironment in hepatocellular carcinoma. | BCL10 correlates with bad prognosis and immune infiltration of tumor microenvironment in hepatocellular carcinoma.
Chen H, Li Z, Wu F, Ji W, Lu L, Wu Z, Huang Y, Wang W, Li S. | 02/27/2023 |
| BCL10 loss-of-function novel mutation leading to atypical severe combined immunodeficiency. | BCL10 loss-of-function novel mutation leading to atypical severe combined immunodeficiency.
Al-Tamemi S, Alhinai Z, Al-Rahbi N, Al-Abdawani R, Al-Yazidi L, Al-Shekaili J, Al-Kindi M, Al-Maawali A. | 08/20/2022 |
| BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. | BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL.
Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW, Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N, Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM., Free PMC Article | 08/13/2022 |
| A nucleation barrier spring-loads the CBM signalosome for binary activation. | A nucleation barrier spring-loads the CBM signalosome for binary activation.
Rodriguez Gama A, Miller T, Lange JJ, Unruh JR, Halfmann R., Free PMC Article | 08/6/2022 |
| TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. | TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO.
Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, Li Z, Gu Y, Chen T, Cao X., Free PMC Article | 03/5/2022 |
| Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population. | Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population.
Guo Y, Cao Y, Gong S, Zhang S, Hou F, Zhang X, Hu J, Yang Z, Yi J, Luo D, Chen X, Song J., Free PMC Article | 07/10/2021 |
| Human BCL10 Deficiency due to Homozygosity for a Rare Allele. | Human BCL10 Deficiency due to Homozygosity for a Rare Allele.
Van Den Rym A, Taur P, Martinez-Barricarte R, Lorenzo L, Puel A, Gonzalez-Navarro P, Pandrowala A, Gowri V, Safa A, Toledano V, Cubillos-Zapata C, López-Collazo E, Vela M, Pérez-Martínez A, Sánchez-Ramón S, Recio MJ, Casanova JL, Desai MM, Perez de Diego R. | 07/3/2021 |
| ZNF436 has a role in promoting tumor cell proliferation through transcriptional activation of BCL10 in glioma | ZNF436 promotes tumor cell proliferation through transcriptional activation of BCL10 in glioma.
Shang Y, Li Y, Zhang Y, Wang J. | 07/11/2020 |
| Deregulated CARD11, BCL10 or MALT1 (CBM) expression or CBM signaling have been associated with immunodeficiency, autoimmunity and cancer. (Review) | Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells.
Lork M, Staal J, Beyaert R. | 04/11/2020 |
| review: BCL10 is involved in the formation of complexes that antagonize apoptosis and contribute to cell survival after DNA damage | BCL10 in cell survival after DNA damage.
Luo Y, Wu J, Zou J, Cao Y, He Y, Ling H, Zeng T. | 12/14/2019 |
| Data indicate the importance of "tuning" caspase recruitment domain family member 11 (CARD11 or CARMA1)-B cell CLL/lymphoma 10 (BCL10)-MALT1 paracaspase (MALT1) complex (CBM) signaling to preserve immune homeostasis [Review]. | The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex.
Lu HY, Bauman BM, Arjunaraja S, Dorjbal B, Milner JD, Snow AL, Turvey SE., Free PMC Article | 10/5/2019 |
| MALT1 activation by TRAF6 in lymphocytes needs neither BCL10 nor CARD11. | MALT1 activation by TRAF6 needs neither BCL10 nor CARD11.
Bardet M, Seeholzer T, Unterreiner A, Woods S, Krappmann D, Bornancin F. | 05/18/2019 |
| CARD9 is a potential target of Zn(2+)-mediated signaling that affects Bcl10 polymerization in innate immune responses. | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.
Holliday MJ, Ferrao R, de Leon Boenig G, Estevez A, Helgason E, Rohou A, Dueber EC, Fairbrother WJ., Free PMC Article | 04/20/2019 |
| MALT1 C-terminal region covering the Ig2-paracaspase-Ig3 domain is flexibly attached to the BCL10-MALT N-terminal death domain core filaments | Molecular architecture and regulation of BCL10-MALT1 filaments.
Schlauderer F, Seeholzer T, Desfosses A, Gehring T, Strauss M, Hopfner KP, Gutsche I, Krappmann D, Lammens K., Free PMC Article | 01/26/2019 |
| High BCL10 expression is associated with Breast Cancer. | The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer.
Ekambaram P, Lee JL, Hubel NE, Hu D, Yerneni S, Campbell PG, Pollock N, Klei LR, Concel VJ, Delekta PC, Chinnaiyan AM, Tomlins SA, Rhodes DR, Priedigkeit N, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC., Free PMC Article | 01/19/2019 |
| Results show that GSK3beta modulates serine phosphorylation of BCL10. | GSK3β modulates NF-κB activation and RelB degradation through site-specific phosphorylation of BCL10.
Abd-Ellah A, Voogdt C, Krappmann D, Möller P, Marienfeld RB., Free PMC Article | 12/22/2018 |
| BCL10 forms CARMA1-BCL10-MALT1-TRAF6 signalosome and BCL10 polymerizes in a unidirectional manner. | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
David L, Li Y, Ma J, Garner E, Zhang X, Wu H., Free PMC Article | 07/21/2018 |
| The results suggest that the involvement of BCL10 in DNA damage-induced NF-kappaB is through the recruitment of TRAF6. | The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival.
Zhang S, Pan D, Jia XM, Lin X, Zhao X., Free PMC Article | 07/21/2018 |
| results define molecular determinants that control the production of Lin(Ub)n-Bcl10, an important signaling intermediate in TCR and oncogenic CARD11 signaling. | Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling.
Yang YK, Yang C, Chan W, Wang Z, Deibel KE, Pomerantz JL., Free PMC Article | 05/27/2017 |
| Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-kappaB activation | Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.
Howes A, O'Sullivan PA, Breyer F, Ghose A, Cao L, Krappmann D, Bowcock AM, Ley SC., Free PMC Article | 05/20/2017 |
| BCL10 promoted DNA double-strand breaks repair, enhancing cell survival after DNA damage. | BCL10 is recruited to sites of DNA damage to facilitate DNA double-strand break repair.
Ismail IH, Dronyk A, Hu X, Hendzel MJ, Shaw AR., Free PMC Article | 10/22/2016 |
| Data show that caspase recruitment domain-containing protein 11/B-cell CLL/lymphoma 10/mucosa-associated lymphoid tissue lymphoma translocation gene 1 signaling drives lymphoproliferation through NF-kappa B and c-Jun N-terminal kinase activation. | Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation.
Knies N, Alankus B, Weilemann A, Tzankov A, Brunner K, Ruff T, Kremer M, Keller UB, Lenz G, Ruland J., Free PMC Article | 08/13/2016 |
| BCL10 is not essential for actin polymerization after fibroblast FcgammaR stimulation. | Actin polymerisation after FCγR stimulation of human fibroblasts is BCL10 independent.
Garcia-Gomez S, Alvarez Doforno R, Martinez-Barricarte R, Torres JM, Ferreira Cerdan A, Davila M, Hernández-Jiménez E, Toledano V, Cubillos-Zapata C, Vallejo-Cremades MT, López-Collazo E, Fernández Arquero M, Sánchez-Ramón S, Casanova JL, Pérez de Diego R. | 07/2/2016 |