| Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression. | Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression.
Adcox HE, Hunt JR, Allen PE, Siff TE, Rodino KG, Ottens AK, Carlyon JA., Free PMC Article | 09/23/2024 |
| NLRC5 exerts anti-endometriosis effects through inhibiting ERbeta-mediated inflammatory response. | NLRC5 exerts anti-endometriosis effects through inhibiting ERβ-mediated inflammatory response.
Guo B, Zhu H, Xiao C, Zhang J, Liu X, Fang Y, Wei B, Zhang J, Cao Y, Zhan L., Free PMC Article | 09/5/2024 |
| CircATXN7 regulates the proliferation and invasion of esophageal cancer cells through miR-4319/NLRC5. | CircATXN7 regulates the proliferation and invasion of esophageal cancer cells through miR-4319/NLRC5.
Guo L, Wang M, Zhao W, Guo M, Qian T, Peng F, Cao G, Yu S, Liu D. | 08/31/2024 |
| NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer. | NLRC5 promotes tumorigenesis by regulating the PI3K/AKT signaling pathway in cervical cancer.
Ling L, Chen J, Zhan L, Fu J, He R, Wang W, Wei B, Ma X, Cao Y., Free PMC Article | 07/9/2024 |
| The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation. | The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation.
Zhu B, Ouda R, An N, Tanaka T, Kobayashi KS., Free PMC Article | 06/5/2024 |
| Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53. | Rescue of NLRC5 expression restores antigen processing machinery in head and neck cancer cells lacking functional STAT1 and p53.
Kinney BLC, Gunti S, Kansal V, Parrish CJ, Saba NF, Teng Y, Henry MK, Su FY, Kwong GA, Schmitt NC., Free PMC Article | 02/6/2024 |
| NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens. | NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens.
Rodriguez GM, Yakubovich E, Murshed H, Maranda V, Galpin KJC, Cudmore A, Hanna AMR, Macdonald E, Ramesh S, Garson K, Vanderhyden BC., Free PMC Article | 01/30/2024 |
| USP14-mediated NLRC5 upregulation inhibits endothelial cell activation and inflammation in atherosclerosis. | USP14-mediated NLRC5 upregulation inhibits endothelial cell activation and inflammation in atherosclerosis.
Fu Y, Qiu J, Wu J, Zhang L, Wei F, Lu L, Wang C, Zeng Z, Liang S, Zheng J. | 08/7/2023 |
| NLRC5 germline variants as potential pharmacogenomic markers for immune checkpoint inhibitors. | NLRC5 germline variants as potential pharmacogenomic markers for immune checkpoint inhibitors.
Meng XY., Free PMC Article | 06/13/2023 |
| NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity. | NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.
Santharam MA, Shukla A, Levesque D, Kufer TA, Boisvert FM, Ramanathan S, Ilangumaran S., Free PMC Article | 05/3/2023 |
| NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2). | NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hao J, Li J, Zhang Z, Yang Y, Zhou Q, Wu T, Chen T, Wu Z, Zhang P, Cui J, Li YP., Free PMC Article | 03/13/2023 |
| NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer. | NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer.
Dong Y, Xu T, Li D, Guo H, Du X, Li G, Chen J, Wang B, Wang P, Yu G, Zhao X, Xue R., Free PMC Article | 02/4/2023 |
| BMI1 induces ubiquitination and protein degradation of Nod-like receptor family CARD domain containing 5 and suppresses human leukocyte antigen class I expression to induce immune escape in non-small cell lung cancer. | BMI1 induces ubiquitination and protein degradation of Nod-like receptor family CARD domain containing 5 and suppresses human leukocyte antigen class I expression to induce immune escape in non-small cell lung cancer.
Lu ZH, Tu GJ, Fu SL, Shang K, Peng SJ, Chen L, Gu XJ. | 12/24/2022 |
| Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic beta cells. | Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells.
Szymczak F, Alvelos MI, Marín-Cañas S, Castela Â, Demine S, Colli ML, Op de Beeck A, Thomaidou S, Marselli L, Zaldumbide A, Marchetti P, Eizirik DL., Free PMC Article | 10/1/2022 |
| NLRC5 modulates phenotypic transition and inflammation of human venous smooth muscle cells by activating Wnt/beta-catenin pathway via TLR4 in varicose veins. | NLRC5 modulates phenotypic transition and inflammation of human venous smooth muscle cells by activating Wnt/β-catenin pathway via TLR4 in varicose veins.
Fang T, Sun S, Zhao B, Dong J, Cao K, Wang W. | 08/20/2022 |
| NLRC5 Might Promote Endometrial Cancer Progression by Inducing PD-L1 Expression. | NLRC5 Might Promote Endometrial Cancer Progression by Inducing PD-L1 Expression.
Zhu SD, Zhang J, Liu XJ, Zhang JH, Wei B, Wang WY, Fan YJ, Li D, Cao YX, Zhan L., Free PMC Article | 07/30/2022 |
| NLRC5 modulates bone metabolism and plays a role in periodontitis. | NLRC5 modulates bone metabolism and plays a role in periodontitis.
Wang W, Liu W, Liu J, Lv P, Wang Y, Ouyang X. | 07/30/2022 |
| Selective autophagy of NLRC5 promotes immune evasion of endometrial cancer. | Selective autophagy of NLRC5 promotes immune evasion of endometrial cancer.
Zhan L, Zhang J, Wei B, Cao Y., Free PMC Article | 07/23/2022 |
| LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer. | LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer.
Zhan L, Zhang J, Zhang J, Liu X, Zhu S, Shi Y, He Y, Wang W, Fan Y, Tang Z, Chen G, Wei B, Cao Y. | 02/26/2022 |
| NLRC5 attenuates inflammatory response in IL-1beta-stimulated human osteoarthritis chondrocytes through the NF-kappaB signaling pathway. | NLRC5 attenuates inflammatory response in IL-1β-stimulated human osteoarthritis chondrocytes through the NF-κB signaling pathway.
Mu Y, Zhang Y, Wu J, Li Q., Free PMC Article | 02/5/2022 |
| Dysregulation of long noncoding RNA MEG3 and NLRC5 expressions in patients with relapsing-remitting multiple sclerosis: is there any correlation? | Dysregulation of long noncoding RNA MEG3 and NLRC5 expressions in patients with relapsing-remitting multiple sclerosis: is there any correlation?
Torkamandi S, Bahrami S, Ghorashi T, Dehani M, Bayat H, Hoseini SM, Rezaei S, Soosanabadi M. | 01/22/2022 |
| NLRC5: A Potential Target for Central Nervous System Disorders. | NLRC5: A Potential Target for Central Nervous System Disorders.
Zhang L, Jiao C, Liu L, Wang A, Tang L, Ren Y, Huang P, Xu J, Mao D, Liu L., Free PMC Article | 12/25/2021 |
| The subcellular redistribution of NLRC5 promotes angiogenesis via interacting with STAT3 in endothelial cells. | The subcellular redistribution of NLRC5 promotes angiogenesis via interacting with STAT3 in endothelial cells.
Xu X, Shi Y, Luan P, Kou W, Li B, Zhai M, You S, Yu Q, Zhuang J, Jian W, Feinberg MW, Peng W., Free PMC Article | 07/31/2021 |
| NLRC5 alleviated OGD/R-induced PC12-cell injury by inhibiting activation of the TLR4/MyD88/NF-kappaB pathway. | NLRC5 alleviated OGD/R-induced PC12-cell injury by inhibiting activation of the TLR4/MyD88/NF-κB pathway.
Zhang Z, Sun Y, Chen X., Free PMC Article | 07/10/2021 |
| miR-4319 Suppresses the Growth of Esophageal Squamous Cell Carcinoma Via Targeting NLRC5. | miR-4319 Suppresses the Growth of Esophageal Squamous Cell Carcinoma Via Targeting NLRC5.
Hu X, Wang M, Cao L, Cong L, Gao Y, Lu J, Feng J, Shen B, Liu D. | 06/12/2021 |