| A Hypoxia Molecular Signature-Based Prognostic Model for Endometrial Cancer Patients. | A Hypoxia Molecular Signature-Based Prognostic Model for Endometrial Cancer Patients.
Jiao Y, Geng R, Zhong Z, Ni S, Liu W, He Z, Gan S, Huang Q, Liu J, Bai J., Free PMC Article | 02/4/2023 |
| the findings of the present study suggest that targeting the Cancerassociated fibroblasts genes, SRPX and HMCN1, can inhibit ovarian cancer migration and invasion. | SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma.
Liu CL, Pan HW, Torng PL, Fan MH, Mao TL. | 04/4/2020 |
| SRPX1 co-accumulated with Abeta deposits in cerebral blood vessels of all autopsied cases with severe cerebral amyloid angiopathy (CAA); no SRPX1 co-accumulated with Abeta deposits in senile plaques. Furthermore, we demonstrated that both Abeta40 and Abeta42 bound to SRPX1 in vitro and enhanced SRPX1 expression in primary cultures of cerebrovascular smooth muscle cells. SRPX1 enhanced caspase activity induced by Abeta40. | Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy.
Inoue Y, Ueda M, Tasaki M, Takeshima A, Nagatoshi A, Masuda T, Misumi Y, Kosaka T, Nomura T, Mizukami M, Matsumoto S, Yamashita T, Takahashi H, Kakita A, Ando Y. | 06/30/2018 |
| The SRPX protein contains the P-DUDES structural domain in its C-terminal region. This domain has significant albeit remote sequence similarity to thioredoxin-like domains, and is predicted to possess an oxidoreductase function. | [A case of mixed tumor of the palate].
Arlotta P, Santori L, de Vecchi A. | 05/28/2013 |
| PELO is subcellularly localized at the actin cytoskeleton, interacts with HAX1, EIF3G and SRPX proteins and that this interaction occurs at the cytoskeleton; this interaction may facilitate PELO to detect and degrade aberrant mRNAs. | Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.
Burnicka-Turek O, Kata A, Buyandelger B, Ebermann L, Kramann N, Burfeind P, Hoyer-Fender S, Engel W, Adham IM., Free PMC Article | 07/12/2010 |
| An apoptosis-inducing protein localized in the endoplasmic reticulum which increases efficiency of apoptosis | A novel apoptotic pathway induced by the drs tumor suppressor gene.
Tambe Y, Isono T, Haraguchi S, Yoshioka-Yamashita A, Yutsudo M, Inoue H. | 01/22/2010 |
| This is the first report demonstrating overexpression of ETX1 in glaucomatous trabecular meshwork. | ETX1 is over-expressed in the glaucomatous trabecular meshwork.
Iragavarapu S, Algeciras ME, Lee RK, Bhattacharya SK., Free PMC Article | 01/21/2010 |
| Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors. | Downregulation of drs tumor suppressor gene in highly malignant human pulmonary neuroendocrine tumors.
Shimakage M, Kodama K, Kawahara K, Kim CJ, Ikeda Y, Yutsudo M, Inoue H. | 01/21/2010 |
| down-regulation of drs mRNA is closely correlated with carcinomas which arise from adenomatous polyps in the course of the adenoma-carcinoma sequence, but most carcinomas arising de novo are independent of the tumor suppressor function of the drs gene | Down-regulation of drs mRNA in colorectal neoplasms.
Mukaisho K, Suo M, Shimakage M, Kushima R, Inoue H, Hattori T., Free PMC Article | 01/21/2010 |
| Down-regulation of drs mRNA is closely correlated with development of prostate carcinoma, suggesting a tumor-suppressor function of the drs gene in this cancer. | Down-regulation of drs mRNA in human prostate carcinomas.
Kim CJ, Shimakage M, Kushima R, Mukaisho K, Shinka T, Okada Y, Inoue H. | 01/21/2010 |
| expression of drs mRNA in well-differentiated, moderately differentiated, and poorly differentiated lung adenocarcinoma tissues (drs; down-regulated by v-scr) | Expression of drs mRNA in human lung adenocarcinomas.
Shimakage M, Takami K, Kodama K, Mano M, Yutsudo M, Inoue H. | 01/21/2010 |