Picalm, a novel regulator of GLUT4-trafficking in adipose tissue. | Picalm, a novel regulator of GLUT4-trafficking in adipose tissue. Gaugel J, Haacke N, Sehgal R, Jähnert M, Jonas W, Hoffmann A, Blüher M, Ghosh A, Noé F, Wolfrum C, Tan J, Schürmann A, Fazakerley DJ, Vogel H., Free PMC Article | 09/24/2024 |
The Effects of PICALM rs3851179 and Age on Brain Atrophy and Cognition Along the Alzheimer's Disease Continuum. | The Effects of PICALM rs3851179 and Age on Brain Atrophy and Cognition Along the Alzheimer's Disease Continuum. Wu Z, Chen J, Liu Y, Yang Y, Feng M, Dai H, Alzheimer’s Disease Neuroimaging Initiative. | 08/26/2024 |
PICALM Variation Moderates the Relationships of APOE varepsilon4 with Alzheimer's Disease Cerebrospinal Biomarkers and Memory Function Among Non-Demented Population. | PICALM Variation Moderates the Relationships of APOE ɛ4 with Alzheimer's Disease Cerebrospinal Biomarkers and Memory Function Among Non-Demented Population. Liu YB, Wang XJ, Tan L, Tan CC, Xu W, Alzheimer’s Disease Neuroimaging Initiative. | 12/21/2023 |
PICALM and Alzheimer's Disease: An Update and Perspectives. | PICALM and Alzheimer's Disease: An Update and Perspectives. Ando K, Nagaraj S, Küçükali F, de Fisenne MA, Kosa AC, Doeraene E, Lopez Gutierrez L, Brion JP, Leroy K., Free PMC Article | 01/14/2023 |
Influence of PICALM and CLU risk variants on beta EEG activity in Alzheimer's disease patients. | Influence of PICALM and CLU risk variants on beta EEG activity in Alzheimer's disease patients. Maturana-Candelas A, Gómez C, Poza J, Rodríguez-González V, Pablo VG, Lopes AM, Pinto N, Hornero R., Free PMC Article | 03/19/2022 |
CALM supports clathrin-coated vesicle completion upon membrane tension increase. | CALM supports clathrin-coated vesicle completion upon membrane tension increase. Willy NM, Colombo F, Huber S, Smith AC, Norton EG, Kural C, Cocucci E., Free PMC Article | 12/4/2021 |
PICALM regulates cathepsin D processing and lysosomal function. | PICALM regulates cathepsin D processing and lysosomal function. Hattersley KJ, Carosi JM, Hein LK, Bensalem J, Sargeant TJ. | 11/22/2021 |
rs3851179G>A in PICALM is Protective Against Alzheimer's Disease in Five Different Countries Surrounding the Mediterranean. | rs3851179G>A in PICALM is Protective Against Alzheimer's Disease in Five Different Countries Surrounding the Mediterranean. Masri I, Salami A, El Shamieh S, Bissar-Tadmouri N. | 10/30/2021 |
PICALM mRNA Expression in the Blood of Patients with Neurodegenerative Diseases and Geriatric Depression. | PICALM mRNA Expression in the Blood of Patients with Neurodegenerative Diseases and Geriatric Depression. Kumon H, Yoshino Y, Funahashi Y, Mori H, Ueno M, Ozaki Y, Yamazaki K, Ochi S, Mori T, Iga JI, Nagai M, Nomoto M, Ueno SI., Free PMC Article | 09/18/2021 |
LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM. | LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM. Zhang F, Wang H, Yu J, Yao X, Yang S, Li W, Xu L, Zhao L., Free PMC Article | 08/14/2021 |
Picalm reduction exacerbates tau pathology in a murine tauopathy model. | Picalm reduction exacerbates tau pathology in a murine tauopathy model. Ando K, De Decker R, Vergara C, Yilmaz Z, Mansour S, Suain V, Sleegers K, de Fisenne MA, Houben S, Potier MC, Duyckaerts C, Watanabe T, Buée L, Leroy K, Brion JP. | 05/22/2021 |
Association of Alzheimer's disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration. | Association of Alzheimer's disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration. Xu W, Tan CC, Cao XP, Tan L, Alzheimer’s Disease Neuroimaging Initiative., Free PMC Article | 05/15/2021 |
Association of PICALM with Cognitive Impairment in Parkinson's Disease. | Association of PICALM with Cognitive Impairment in Parkinson's Disease. Periñán MT, Macías-García D, Labrador-Espinosa MÁ, Jesús S, Buiza-Rueda D, Adarmes-Gómez AD, Muñoz-Delgado L, Gómez-Garre P, Mir P. | 05/8/2021 |
Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer's disease patients. | Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer's disease patients. Mitsumori R, Sakaguchi K, Shigemizu D, Mori T, Akiyama S, Ozaki K, Niida S, Shimoda N., Free PMC Article | 11/21/2020 |
Association of PICALM Gene Polymorphisms with Alzheimer's Disease: Evidence from an Updated Meta-Analysis. | Association of PICALM Gene Polymorphisms with Alzheimer's Disease: Evidence from an Updated Meta-Analysis. Zeng FF, Liu J, He H, Gao XP, Liao MQ, Yu XX, Liu YH, Zhu S, Jing CX. | 10/10/2020 |
results indicate a modulating effect of PTB-APs on PICALM-mediated APP endocytosis and localization. | The role of PTB domain containing adaptor proteins on PICALM-mediated APP endocytosis and localization. Merthan L, Haller A, Thal DR, von Einem B, von Arnim CAF. | 03/21/2020 |
CircPICALM can inhibit BC metastasis and bind to miR-1265 to block its pro-invasion activity. | Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation. Yan D, Dong W, He Q, Yang M, Huang L, Kong J, Qin H, Lin T, Huang J., Free PMC Article | 03/21/2020 |
PICALM may modulate memory deficits and decrease metabolic connectivity in APOE-epsilon4 carriers with Alzheimer disease. | Genetic interaction is associated with lower metabolic connectivity and memory impairment in clinically mild Alzheimer's disease. Chang YT, Huang CW, Huang SH, Hsu SW, Chang WN, Lee JJ, Chang CC. | 01/4/2020 |
The data of this study suggest a possible role of PICALM methylation in Alzheimer's Disease, particularly related to cognitive function. | PICALM Gene Methylation in Blood of Alzheimer's Disease Patients Is Associated with Cognitive Decline. Mercorio R, Pergoli L, Galimberti D, Favero C, Carugno M, Dalla Valle E, Barretta F, Cortini F, Scarpini E, Valentina VB, Pesatori AC. | 08/3/2019 |
the PICALM rs3851179 polymorphism was associated with Alzheimer's disease; the APOE epsilon4 status did not influence the relationship (Meta-Analysis) | Correlation of PICALM polymorphism rs3851179 with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review. Zhu B, Li LX, Zhang L, Yang S, Tian Y, Guo SS, Zhang W, Zhao ZG. | 06/29/2019 |
the Single nucleotide polymorphisms rs11136000 of CLU, rs541458 of PICALM, and rs1554948 of TNK1 according to the three age groups 50-65 years (group 1), 66-80 years (group 2), and 80+ years (group 3) in 569 older subjects without cognitive impairment (NoCI) and 520 Alzheimer's disease (AD) patients, were studied. | Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease. Seripa D, Panza F, Paroni G, D'Onofrio G, Bisceglia P, Gravina C, Urbano M, Lozupone M, Solfrizzi V, Bizzarro A, Boccardi V, Piccininni C, Daniele A, Logroscino G, Mecocci P, Masullo C, Greco A. | 02/9/2019 |
interactive effects of rs541458 x age existed with regard to executive function and processing speed after controlling for gender, years of education and APOE epsilon4 status. | The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly. Liu Z, Dai X, Zhang J, Li X, Chen Y, Ma C, Chen K, Peng D, Zhang Z., Free PMC Article | 01/12/2019 |
IN PICALM rs3851179 polymorphism, the age- dependent increase in the P3 latency was more pronounced in the PICALM GG carriers than in the carriers of the PICALM AA and PICALM AG genotypes. | Genetic Association between Alzheimer's Disease Risk Variant of the PICALM Gene and Auditory Event-Related Potentials in Aging. Ponomareva NV, Andreeva TV, Protasova MA, Filippova YV, Kolesnikova EP, Fokin VF, Illarioshkin SN, Rogaev EI. | 12/26/2018 |
There were significant differences in genotype and allele frequencies for the SNP PICALM rs3851179 between Brazilian Alzheimer and Parkinson disease cases and controls, but none for CR1 rs6656401 and CLU rs11136000 intronic polymorphisms. | rs3851179 Polymorphism at 5' to the PICALM Gene is Associated with Alzheimer and Parkinson Diseases in Brazilian Population. Santos-Rebouças CB, Gonçalves AP, Dos Santos JM, Abdala BB, Motta LB, Laks J, de Borges MB, de Rosso ALZ, Pereira JS, Nicaretta DH, Pimentel MMG. | 08/11/2018 |
The PICALM rs3851179 polymorphism significantly affects the default mode network network in mild cognitive impairment | Effect of PICALM rs3851179 polymorphism on the default mode network function in mild cognitive impairment. Sun DM, Chen HF, Zuo QL, Su F, Bai F, Liu CF. | 04/7/2018 |