| Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells. | Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells.
Audu CO, Wolf SJ, Joshi AD, Moon JY, Melvin WJ, Sharma SB, Davis FM, Obi AT, Wasikowski R, Tsoi LC, Barrett EC, Mangum KD, Bauer TM, Kunkel SL, Moore BB, Gallagher KA., Free PMC Article | 07/11/2024 |
| Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. | Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.
Deogharia M, Venegas-Zamora L, Agrawal A, Shi M, Jain AK, McHugh KJ, Altamirano F, Marian AJ, Gurha P., Free PMC Article | 05/29/2024 |
| KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity. | KDM5C-Mediated Recruitment of BRD4 to Chromatin Regulates Enhancer Activation and BET Inhibitor Sensitivity.
Qiang Y, Fan J, Xie C, Yan L, Song X, Zhang N, Lin Y, Xiong J, Zhang W, Liu Y, Wei L, Li Y, Chen S, Liang K, Li F. | 05/13/2024 |
| WNT signalling control by KDM5C during development affects cognition. | WNT signalling control by KDM5C during development affects cognition.
Karwacki-Neisius V, Jang A, Cukuroglu E, Tai A, Jiao A, Predes D, Yoon J, Brookes E, Chen J, Iberg A, Halbritter F, Õunap K, Gecz J, Schlaeger TM, Ho Sui S, Göke J, He X, Lehtinen MK, Pomeroy SL, Shi Y., Free PMC Article | 04/3/2024 |
| Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression. | Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression.
Yu F, Li L, Gu Y, Wang S, Zhou L, Cheng X, Jiang H, Huang Y, Zhang Y, Qian W, Li X, Liu Z., Free PMC Article | 01/27/2024 |
| KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas. | KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.
Wang D, Zhang Y, Liao Z, Ge H, Güngör C, Li Y., Free PMC Article | 11/13/2023 |
| The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system. | The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system.
Fazazi MR, Ruda GF, Brennan PE, Rangachari M. | 09/28/2023 |
| Elevated PSPC1 and KDM5C expression indicates poor prognosis in prostate cancer. | Elevated PSPC1 and KDM5C expression indicates poor prognosis in prostate cancer.
Lemster AL, Weingart A, Bottner J, Perner S, Sailer V, Offermann A, Kirfel J. | 08/16/2023 |
| The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts. | The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts.
Liu H, Zhai L, Liu Y, Lu D, Vander Ark A, Yang T, Krawczyk CM., Free PMC Article | 04/7/2023 |
| The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes. | The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes.
Trempenau ML, Schuster MB, Pundhir S, Pereira MA, Kalvisa A, Tapia M, Su J, Ge Y, de Boer B, Balhuizen A, Bagger FO, Shliaha P, Sroczynska P, Walfridsson J, Grønbæk K, Theilgaard-Mönch K, Jensen ON, Helin K, Porse BT., Free PMC Article | 03/11/2023 |
| Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations. | Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations.
Ugur FS, Kelly MJS, Fujimori DG., Free PMC Article | 03/10/2023 |
| Expanding the genetics and phenotypic spectrum of Lysine-specific demethylase 5C (KDM5C): a report of 13 novel variants. | Expanding the genetics and phenotypic spectrum of Lysine-specific demethylase 5C (KDM5C): a report of 13 novel variants.
Leonardi E, Aspromonte MC, Drongitis D, Bettella E, Verrillo L, Polli R, McEntagart M, Licchetta L, Dilena R, D'Arrigo S, Ciaccio C, Esposito S, Leuzzi V, Torella A, Baldo D, Lonardo F, Bonato G, Pellegrin S, Stanzial F, Posmyk R, Kaczorowska E, Carecchio M, Gos M, Rzońca-Niewczas S, Miano MG, Murgia A., Free PMC Article | 02/13/2023 |
| Molecular and cellular events linking variants in the histone demethylase KDM5C to the intellectual disability disorder Claes-Jensen syndrome. | Molecular and cellular events linking variants in the histone demethylase KDM5C to the intellectual disability disorder Claes-Jensen syndrome.
Hatch HAM, Secombe J., Free PMC Article | 12/31/2022 |
| Lysine (K)-specific demethylase 5C regulates the incidence of severe preeclampsia by adjusting the expression of bone morphogenetic protein-7. | Lysine (K)-specific demethylase 5C regulates the incidence of severe preeclampsia by adjusting the expression of bone morphogenetic protein-7.
Shi XF, Zhang Z, Wu HY, Wang Y, Chang AM, Gao JJ, Liu K, Song WY, Wang L, Wang HP., Free PMC Article | 05/7/2022 |
| Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma. | Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma.
Qian X, Bao ZM, Yao D, Shi Y. | 04/30/2022 |
| HOXD3 Up-regulating KDM5C Promotes Malignant Progression of Diffuse Large B-Cell Lymphoma by Decreasing p53 Expression | HOXD3 Up-regulating KDM5C Promotes Malignant Progression of Diffuse Large B-Cell Lymphoma by Decreasing p53 Expression.
Cui Y, Lv C, Wen Y, Zhao D, Yang Y, Qiu H, Wang C., Free PMC Article | 04/16/2022 |
| Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures. | Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures.
Poeta L, Padula A, Lioi MB, van Bokhoven H, Miano MG., Free PMC Article | 02/19/2022 |
| Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis. | Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis.
Zheng Q, Li P, Zhou X, Qiang Y, Fan J, Lin Y, Chen Y, Guo J, Wang F, Xue H, Xiong J, Li F., Free PMC Article | 02/5/2022 |
| Caregiver-reported characteristics of children diagnosed with pathogenic variants in KDM5C. | Caregiver-reported characteristics of children diagnosed with pathogenic variants in KDM5C.
Hatch HAM, O'Neil MH, Marion RW, Secombe J, Shulman LH., Free PMC Article | 01/22/2022 |
| X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis. | X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.
Tricarico R, Nicolas E, Hall MJ, Golemis EA., Free PMC Article | 11/27/2021 |
| The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis. | The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis.
Shen HF, Zhang WJ, Huang Y, He YH, Hu GS, Wang L, Peng BL, Yi J, Li TT, Rong R, Chen XY, Liu JY, Li WJ, Ohgi K, Li SW, Rosenfeld MG, Liu W., Free PMC Article | 11/22/2021 |
| Predictive Value of KDM5C Alterations for Immune Checkpoint Inhibitors Treatment Outcomes in Patients With Cancer. | Predictive Value of KDM5C Alterations for Immune Checkpoint Inhibitors Treatment Outcomes in Patients With Cancer.
Chen XJ, Ren AQ, Zheng L, Zheng ED., Free PMC Article | 10/30/2021 |
| Further delineation of the female phenotype with KDM5C disease causing variants: 19 new individuals and review of the literature. | Further delineation of the female phenotype with KDM5C disease causing variants: 19 new individuals and review of the literature.
Carmignac V, Nambot S, Lehalle D, Callier P, Moortgat S, Benoit V, Ghoumid J, Delobel B, Smol T, Thuillier C, Zordan C, Naudion S, Bienvenu T, Touraine R, Ramond F, Zweier C, Reis A, Kraus C, Nizon M, Cogné B, Verloes A, Tran Mau-Them F, Sorlin A, Jouan T, Duffourd Y, Tisserant E, Philippe C, Vitobello A, Thevenon J, Faivre L, Thauvin-Robinet C. | 07/10/2021 |
| Relationship between visceral adipose tissue and genetic mutations (VHL and KDM5C) in clear cell renal cell carcinoma. | Relationship between visceral adipose tissue and genetic mutations (VHL and KDM5C) in clear cell renal cell carcinoma.
Greco F, Mallio CA. | 05/1/2021 |
| [Clinical features and gene variant of a pedigree affected with X-linked recessive mental retardation Claes-Jensen type]. | [Clinical features and gene variant of a pedigree affected with X-linked recessive mental retardation Claes-Jensen type].
Ding N, Zhang P, Mao Y, Feng S, Gao Z, Chen Q, Zhang X. | 01/9/2021 |