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    HSI2 B3 domain-containing transcription repressor VAL1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817597, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Brassinosteroids repress the seed maturation program during the seed-to-seedling transition.

    Brassinosteroids repress the seed maturation program during the seed-to-seedling transition.
    Ruan J, Chen H, Zhu T, Yu Y, Lei Y, Yuan L, Liu J, Wang ZY, Kuang JF, Lu WJ, Huang S, Li C., Free PMC Article

    02/19/2022
    EAR domain-containing transcription factors trigger PRC2-mediated chromatin marking in Arabidopsis.

    EAR domain-containing transcription factors trigger PRC2-mediated chromatin marking in Arabidopsis.
    Baile F, Merini W, Hidalgo I, Calonje M., Free PMC Article

    01/1/2022
    VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms.

    VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms.
    Fouracre JP, He J, Chen VJ, Sidoli S, Poethig RS., Free PMC Article

    10/16/2021
    The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis.

    The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis.
    Yuan L, Song X, Zhang L, Yu Y, Liang Z, Lei Y, Ruan J, Tan B, Liu J, Li C., Free PMC Article

    01/23/2021
    The B3-Domain Transcription Factor VAL1 Regulates the Floral Transition by Repressing FLOWERING LOCUS T.

    The B3-Domain Transcription Factor VAL1 Regulates the Floral Transition by Repressing FLOWERING LOCUS T.
    Jing Y, Guo Q, Lin R., Free PMC Article

    09/5/2020
    Structural basis for the Sph/RY sequence recognition by VAL1/2 transcriptional repressor.

    Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1.
    Sasnauskas G, Kauneckaite K, Siksnys V., Free PMC Article

    08/10/2019
    VAL1 crystal structure provides insight into the important implication of VAL1-B3 domain in flowering process.

    Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana.
    Wu B, Zhang M, Su S, Liu H, Gan J, Ma J.

    11/10/2018
    The results suggest that HSI2 recruits MED13 and HDA6 to suppress directly a subset of seed maturation genes post-germination.

    HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth.
    Chhun T, Chong SY, Park BS, Wong EC, Yin JL, Kim M, Chua NH.

    06/24/2017
    LEC1, LEC2 , and FUSCA3 transcripts are candidate targets of VAL1, acting through epigenetic and/or transcriptional repression.

    Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos.
    Schneider A, Aghamirzaie D, Elmarakeby H, Poudel AN, Koo AJ, Heath LS, Grene R, Collakova E.

    10/22/2016
    VAL1 localizes to the nucleation region in vivo, promoting histone deacetylation and FLOWERING LOCUS C transcriptional silencing, and interacts with components of the conserved apoptosis- and splicing-associated protein complex.

    Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization.
    Qüesta JI, Song J, Geraldo N, An H, Dean C.

    10/8/2016
    HSI2 PHD-like domain in the regulation of gene expression involving histone modifications and DNA methylation-mediated epigenetic mechanisms.

    HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings.
    Veerappan V, Chen N, Reichert AI, Allen RD., Free PMC Article

    02/6/2016
    These results implicate HSI2 as a negative regulator of drought stress response in Arabidopsis.

    High-level expression of sugar inducible gene2 (HSI2) is a negative regulator of drought stress tolerance in Arabidopsis.
    Sharma N, Bender Y, Boyle K, Fobert PR., Free PMC Article

    08/16/2014
    A novel HSI2 mutant allele, hsi2-4, was identified that exhibits constitutively elevated luciferase expression while expression of the endogenous GSTF8 transcript remains unchanged. Microarray analysis indicated that the HSI2 PHD-like domain functions non-redundantly to repress a subset of seed maturation genes. [HSI2]

    A novel HSI2 mutation in Arabidopsis affects the PHD-like domain and leads to derepression of seed-specific gene expression.
    Veerappan V, Wang J, Kang M, Lee J, Tang Y, Jha AK, Shi H, Palanivelu R, Allen RD.

    07/7/2014
    These results indicate that HSI2 and related proteins are B3 domain-EAR motif active transcription repressors. [HSI2]

    Analysis of a sugar response mutant of Arabidopsis identified a novel B3 domain protein that functions as an active transcriptional repressor.
    Tsukagoshi H, Saijo T, Shibata D, Morikami A, Nakamura K., Free PMC Article

    01/21/2010
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