| LAT1 supports mitotic progression through Golgi unlinking in an amino acid transport activity-independent manner. | LAT1 supports mitotic progression through Golgi unlinking in an amino acid transport activity-independent manner.
Yanagida S, Yuki R, Saito Y, Nakayama Y., Free PMC Article | 11/7/2024 |
| TP63 transcriptionally regulates SLC7A5 to suppress ferroptosis in head and neck squamous cell carcinoma. | TP63 transcriptionally regulates SLC7A5 to suppress ferroptosis in head and neck squamous cell carcinoma.
Chen Z, Cai H, Ye W, Wu J, Liu J, Xie Y, Feng S, Jin Y, Lv Y, Ye H, Cai C, Cai G., Free PMC Article | 10/25/2024 |
| TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts. | TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts.
Yang B, Wang Z, Niu K, Li T, Tong T, Li S, Su L, Wang Y, Shen C, Jin X, Song J, Lu X., Free PMC Article | 09/29/2024 |
| LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2alpha accumulation under experimental hypoxia. | LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia.
Ohgaki R, Hirase Y, Xu M, Okanishi H, Kanai Y., Free PMC Article | 08/26/2024 |
| MRPL35 Induces Proliferation, Invasion, and Glutamine Metabolism in NSCLC Cells by Upregulating SLC7A5 Expression. | MRPL35 Induces Proliferation, Invasion, and Glutamine Metabolism in NSCLC Cells by Upregulating SLC7A5 Expression.
Hou W, Chen J, Wang Y., Free PMC Article | 08/2/2024 |
| Fat mass and obesity-associated protein (FTO) mediated m[6]A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay. | Fat mass and obesity-associated protein (FTO) mediated m(6)A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay.
Wu X, Fang Y, Gu Y, Shen H, Xu Y, Xu T, Shi R, Xu D, Zhang J, Leng K, Shu Y, Ma P., Free PMC Article | 06/5/2024 |
| [Effect of L-Type Amino Acid Transporter 1 Expression on Clinicopathological Features and Prognosis of Non-Hodgkin's Lymphoma]. | [Effect of L-Type Amino Acid Transporter 1 Expression on Clinicopathological Features and Prognosis of Non-Hodgkin's Lymphoma].
Zhao ZF, Hao XJ, Yang YM, Xu WG, Zhang YX, Yuan XH. | 05/17/2024 |
| Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling. | Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling.
Rosario FJ, Urschitz J, Powell TL, Brown TL, Jansson T., Free PMC Article | 11/16/2023 |
| MicroRNA-626 inhibits mTOR pathways activity of retinal pigment epithelial cells by targeting SLC7A5 in human ARPE-19 Cells. | MicroRNA-626 inhibits mTOR pathways activity of retinal pigment epithelial cells by targeting SLC7A5 in human ARPE-19 Cells.
Ercan Ç, Elbay A, Aslan ES, Akbaş F, Ozdemir H, Ozgentürk NO. | 11/14/2023 |
| Targeting glutamine metabolic reprogramming of SLC7A5 enhances the efficacy of anti-PD-1 in triple-negative breast cancer. | Targeting glutamine metabolic reprogramming of SLC7A5 enhances the efficacy of anti-PD-1 in triple-negative breast cancer.
Huang R, Wang H, Hong J, Wu J, Huang O, He J, Chen W, Li Y, Chen X, Shen K, Wang Z., Free PMC Article | 09/26/2023 |
| CD98 expression can be a predictive factor of resistance to radiotherapy in head and neck squamous cell carcinoma. | CD98 expression can be a predictive factor of resistance to radiotherapy in head and neck squamous cell carcinoma.
Suzuki H, Kawasaki Y, Suzuki S, Yamada T, Ito A, Suzuki M, Miura M, Hatakeyama H, Omori Y. | 09/22/2023 |
| Impact of L-type amino acid transporter 1 on intrahepatic cholangiocarcinoma. | Impact of L-type amino acid transporter 1 on intrahepatic cholangiocarcinoma.
Selenge B, Yamada S, Morine Y, Ikemoto T, Saito Y, Takasu C, Teraoku H, Okikawa S, Shimada M. | 05/17/2023 |
| Association of High LAT1 Expression with Poor Prognosis and Recurrence in Colorectal Cancer Patients Treated with Oxaliplatin-Based Adjuvant Chemotherapy. | Association of High LAT1 Expression with Poor Prognosis and Recurrence in Colorectal Cancer Patients Treated with Oxaliplatin-Based Adjuvant Chemotherapy.
Shibasaki Y, Yokobori T, Sohda M, Shioi I, Ozawa N, Komine C, Suga K, Nakazawa N, Osone K, Shiraishi T, Okada T, Sano A, Sakai M, Ogawa H, Kaira K, Shirabe K, Saeki H., Free PMC Article | 02/16/2023 |
| CD98 defines a metabolically flexible, proinflammatory subset of low-density neutrophils in systemic lupus erythematosus. | CD98 defines a metabolically flexible, proinflammatory subset of low-density neutrophils in systemic lupus erythematosus.
Martin KR, Day JA, Hansen JA, D'Silva DB, Wong HL, Garnham A, Sandow JJ, Nijagal B, Wilson N, Wicks IP., Free PMC Article | 01/28/2023 |
| Correlation between the expression of LAT1 in cancer cells and the potential efficacy of boron neutron capture therapy. | Correlation between the expression of LAT1 in cancer cells and the potential efficacy of boron neutron capture therapy.
Watanabe T, Sanada Y, Hattori Y, Suzuki M., Free PMC Article | 01/28/2023 |
| Co-expression effect of LLGL2 and SLC7A5 to predict prognosis in ERalpha-positive breast cancer. | Co-expression effect of LLGL2 and SLC7A5 to predict prognosis in ERα-positive breast cancer.
Hisada T, Kondo N, Wanifuchi-Endo Y, Osaga S, Fujita T, Asano T, Uemoto Y, Nishikawa S, Katagiri Y, Terada M, Kato A, Sugiura H, Okuda K, Kato H, Komura M, Morita S, Takahashi S, Toyama T., Free PMC Article | 10/8/2022 |
| The role of L-type amino acid transporter 1 (Slc7a5) during in vitro myogenesis. | The role of L-type amino acid transporter 1 (Slc7a5) during in vitro myogenesis.
Collao N, Akohene-Mensah P, Nallabelli J, Binet ER, Askarian A, Lloyd J, Niemiro GM, Beals JW, van Vliet S, Rajgara R, Saleh A, Wiper-Bergeron N, Paluska SA, Burd NA, De Lisio M. | 08/27/2022 |
| Increased expression of LAT1 in basal cell carcinoma: implications for tumour cell survival. | Increased expression of LAT1 in basal cell carcinoma: implications for tumour cell survival.
Prosén S, Tina E, Sneckenborg AH, Loinder C, Seifert O, Lindberg M, Eremo AG. | 05/7/2022 |
| SLC7A5 expression is up-regulated in peripheral blood T and B lymphocytes of systemic lupus erythematosus patients, associating with renal damage. | SLC7A5 expression is up-regulated in peripheral blood T and B lymphocytes of systemic lupus erythematosus patients, associating with renal damage.
Tian J, Li X, Jiang Y, Gao F, Ju B, Chen J, Zhu W, He L, Meng L, Lu S. | 05/7/2022 |
| Vitamin D stimulates placental L-type amino acid transporter 1 (LAT1) in preeclampsia. | Vitamin D stimulates placental L-type amino acid transporter 1 (LAT1) in preeclampsia.
Jia X, Cao Y, Ye L, Liu X, Huang Y, Yuan X, Lu C, Xu J, Zhu H., Free PMC Article | 05/7/2022 |
| CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis. | CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis.
Geng J, Chen R, Yang FF, Lin P, Zhu YM, Fu X, Wang K, Feng Z, Wu J, Zhang H, Li QJ, Chen ZN, Zhu P., Free PMC Article | 04/9/2022 |
| Overexpression of miR-375 and L-type Amino Acid Transporter 1 in Pheochromocytoma and Their Molecular and Functional Implications. | Overexpression of miR-375 and L-type Amino Acid Transporter 1 in Pheochromocytoma and Their Molecular and Functional Implications.
Manso J, Bertazza L, Barollo S, Mondin A, Censi S, Carducci S, Ferrara AM, Boschin IM, Zovato S, Schiavi F, Gregianin M, Pennelli G, Iacobone M, Mian C., Free PMC Article | 03/26/2022 |
| Expression profile of CD98 heavy chain and L-type amino acid transporter 1 and its prognostic significance in colorectal cancer. | Expression profile of CD98 heavy chain and L-type amino acid transporter 1 and its prognostic significance in colorectal cancer.
Lee D, Kim HS, Kim HU, Song HJ, Lee C, Kim DY, Chun HM, Jang WY, Jang B. | 03/26/2022 |
| First-in-human assessment of the novel LAT1 targeting PET probe (18)F-FIMP. | First-in-human assessment of the novel LAT1 targeting PET probe (18)F-FIMP.
Nozaki S, Nakatani Y, Mawatari A, Hume WE, Wada Y, Ishii A, Tanaka M, Tsuyuguchi N, Doi H, Watanabe Y. | 03/19/2022 |
| Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer. | Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer.
Kurozumi S, Kaira K, Matsumoto H, Kurosumi M, Yokobori T, Kanai Y, Sekine C, Honda C, Katayama A, Furuya M, Shiino S, Makiguchi T, Mongan NP, Rakha EA, Oyama T, Fujii T, Shirabe K, Horiguchi J., Free PMC Article | 03/12/2022 |