| The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis. | The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis.
Wu S, Liu M, Zhang M, Ye X, Gu H, Jiang C, Zhu H, Ye X, Li Q, Huang X, Cao M., Free PMC Article | 03/21/2024 |
| Upregulation of CALD1 predicted a poor prognosis for platinum-treated ovarian cancer and revealed it as a potential therapeutic resistance target. | Upregulation of CALD1 predicted a poor prognosis for platinum-treated ovarian cancer and revealed it as a potential therapeutic resistance target.
Li W, Huang L, Qi N, Zhang Q, Qin Z., Free PMC Article | 03/1/2024 |
| METTL14 Promotes Oral Squamous Cell Carcinoma Progression by Regulating the mRNA and m6A Levels of CALD1. | METTL14 Promotes Oral Squamous Cell Carcinoma Progression by Regulating the mRNA and m6A Levels of CALD1.
Chen R, Zhang S, Li H, Yang M, Lu Y, Zhang X. | 04/7/2023 |
| Proteomic analysis revealed a group of molecules associated with cytoskeleton organization, including caldesmon, were differentially expressed between fibroblasts isolated from bone destruction non-functioning pituitary adenomas (BD-NFPAs) and fibroblasts isolated from non-bone destruction NFPAs (NBD-NFPAs). The secreted proteins analysis found that osteopontin was significantly upregulated in BD-NFPAs fibroblasts. | Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas.
Zhang LY, Ge XL, Li Z, Tang YJ, Xiong YY, Li XJ, Liu JF, Wanggou SY, Li CT, Yang K, Chen X, Hu ZL, Liu YS, Liu ZX., Free PMC Article | 08/17/2019 |
| rs 3807337 polymorphism of CALD1 gene is associated with diabetic nephropathy occurrence in type 1 diabetes. | Association of rs 3807337 polymorphism of CALD1 gene with diabetic nephropathy occurrence in type 1 diabetes - preliminary results of a family-based study.
Śnit M, Nabrdalik K, Długaszek M, Gumprecht J, Trautsolt W, Górczyńska-Kosiorz S, Grzeszczak W. | 05/6/2017 |
| ANXA1 and CALD1 proteins are independent markers for tamoxifen therapy outcome and are associated to fast tumor progression. | Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer.
De Marchi T, Timmermans AM, Smid M, Look MP, Stingl C, Opdam M, Linn SC, Sweep FC, Span PN, Kliffen M, van Deurzen CH, Luider TM, Foekens JA, Martens JW, Umar A., Free PMC Article | 12/17/2016 |
| Data indicate that low-molecular-weight caldesmon isoforms (L-CAD) promotes migration and invasiveness of urothelial bladder carcinoma (BC) cells. | Overexpression of caldesmon is associated with tumor progression in patients with primary non-muscle-invasive bladder cancer.
Lee MS, Lee J, Kim JH, Kim WT, Kim WJ, Ahn H, Park J., Free PMC Article | 09/24/2016 |
| Caldesmon and smoothelin staining allows better delineation of the muscularis propria from the desmoplastic stromal reaction which provides a critical aide for proper staging of colonic adenocarcinomas. | Smoothelin and caldesmon are reliable markers for distinguishing muscularis propria from desmoplasia: a critical distinction for accurate staging colorectal adenocarcinoma.
Roberts JA, Waters L, Ro JY, Zhai QJ., Free PMC Article | 10/18/2014 |
| caldesmon is not useful in distinguishing between peritoneal epithelioid mesotheliomas and papillary serous carcinomas involving the peritoneum | Value of PAX8, PAX2, claudin-4, and h-caldesmon immunostaining in distinguishing peritoneal epithelioid mesotheliomas from serous carcinomas.
Ordóñez NG. | 11/16/2013 |
| The data suggest that PKGIbeta enhances breast cancer cell motility and invasive capacity, at least in part, by phosphorylating CaD. | cGMP-dependent protein kinase Iβ regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon.
Schwappacher R, Rangaswami H, Su-Yuo J, Hassad A, Spitler R, Casteel DE., Free PMC Article | 11/2/2013 |
| Caldesmon is a possible predictor of endometrial dysregulation in patients with endometriosis. | Caldesmon: new insights for diagnosing endometriosis.
Meola J, Hidalgo Gdos S, Silva JC, Silva LE, Paz CC, Ferriani RA. | 10/26/2013 |
| Caldesmon expression inhibits cancer cell migration and invasiveness. | Identification and functional validation of caldesmon as a potential gastric cancer metastasis-associated protein.
Hou Q, Tan HT, Lim KH, Lim TK, Khoo A, Tan IB, Yeoh KG, Chung MC. | 07/6/2013 |
| Disruption of the normal inhibitory function of human caldesmon 1 enhances intestinal peristalsis in both wild-type zebrafish larvae and mutant larvae that lack enteric nerves | Smooth muscle caldesmon modulates peristalsis in the wild type and non-innervated zebrafish intestine.
Abrams J, Davuluri G, Seiler C, Pack M., Free PMC Article | 05/26/2012 |
| Data found phasic phosphorylation of caldesmon and ERK 1/2 during contractions in human myometrium. | Phasic phosphorylation of caldesmon and ERK 1/2 during contractions in human myometrium.
Paul J, Maiti K, Read M, Hure A, Smith J, Chan EC, Smith R., Free PMC Article | 12/3/2011 |
| Our results show a differential behavior of h- and l-caldesmon isoforms in epithelium and stroma of colon adenocarcinoma and lymph node metastases. | Histochemical localization of caldesmon isoforms in colon adenocarcinoma and lymph node metastases.
Köhler C. | 09/3/2011 |
| Novel biological cascade that involved the phosphorylation activation of CaD by PFTK1 kinase in promoting formation of actin stress fibers. | Phosphorylation of Caldesmon by PFTAIRE1 kinase promotes actin binding and formation of stress fibers.
Leung WK, Ching AK, Wong N. | 07/16/2011 |
| An involvement of caldesmon in the susceptibility to diabetic nephropathy in type 1 diabetes, independently from environmental glucose levels. | Caldesmon over-expression in type 1 diabetic nephropathy.
Millioni R, Iori E, Lenzini L, Puricelli L, Caroccia B, Arrigoni G, Rossi GP, Tessari P. | 06/25/2011 |
| h-caldesmon is useful in distinguishing atypical polypoid adenomyoma from myoinvasive endometrioid carcinoma | Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to h-caldesmon.
Horita A, Kurata A, Maeda D, Fukayama M, Sakamoto A. | 04/9/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Stretch activates myometrium via ERK, caldesmon and focal adhesion signaling | Stretch activates human myometrium via ERK, caldesmon and focal adhesion signaling.
Li Y, Reznichenko M, Tribe RM, Hess PE, Taggart M, Kim H, DeGnore JP, Gangopadhyay S, Morgan KG., Free PMC Article | 03/15/2010 |
| Results describe the mechanisms of PC6 action in decidualization and identify caldesmon as one of its physiological substrates. | Proteomic identification of caldesmon as a physiological substrate of proprotein convertase 6 in human uterine decidual cells essential for pregnancy establishment.
Kilpatrick LM, Stephens AN, Hardman BM, Salamonsen LA, Li Y, Stanton PG, Nie G. | 02/22/2010 |
| The effect of a C-terminal fragment of CaD (H32K) on the kinetics of the in vitro actin polymerization by monitoring the fluorescence of pyrene-labeled actin, was studied. | Differential effects of caldesmon on the intermediate conformational states of polymerizing actin.
Huang R, Grabarek Z, Wang CL., Free PMC Article | 02/1/2010 |
| Vaginal caldesmon expression is significantly decreased in women with anterior vaginal wall prolapse compared to normal subjects | Caldesmon expression is decreased in women with anterior vaginal wall prolapse: a pilot study.
Takacs P, Gualtieri M, Nassiri M, Candiotti K, Fornoni A, Medina CA. | 01/21/2010 |
| GR directly bound to the two glucocorticoid-response element-like sequences in the human CALD1 promoter and transactivated the CALD1 gene, thereby up-regulating the CaD protein. | Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K., Free PMC Article | 01/21/2010 |
| A subset of the tumor-specific splicing alterations (ACTN1, CALD1, and VCL) was found in all three organs and may represent general cancer-related splicing events. | Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis.
Thorsen K, Sørensen KD, Brems-Eskildsen AS, Modin C, Gaustadnes M, Hein AM, Kruhøffer M, Laurberg S, Borre M, Wang K, Brunak S, Krainer AR, Tørring N, Dyrskjøt L, Andersen CL, Orntoft TF. | 01/21/2010 |