| EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells. | EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.
Tian Q, Chen JH, Ding Y, Wang XY, Qiu JY, Cao Q, Zhuang LL, Jin R, Zhou GP. | 02/29/2024 |
| SVEP1 influences monocyte to macrophage differentiation via integrin alpha4beta1/alpha9beta1 and Rho/Rac signalling. | SVEP1 influences monocyte to macrophage differentiation via integrin α4β1/α9β1 and Rho/Rac signalling.
Andrews SL, Ghaderi-Najafabadi M, Gong P, Shamkhi N, Carleton L, Schofield C, Kessler T, Samani NJ, Webb TR, Morris GE. | 06/13/2023 |
| Effects of SVEP1 on Lung Squamous Cell Carcinoma and its Association with Tumor Mutation Burden, Prognosis, and Immune Regulation. | Effects of SVEP1 on Lung Squamous Cell Carcinoma and its Association with Tumor Mutation Burden, Prognosis, and Immune Regulation.
Luo Y, Zhang M, Wang Z, Li Z, Chen X, Cao J, Que J, Chen L, Deng X. | 03/9/2023 |
| Decreased expression of SVEP1 is closely related to a cancer stem cell-like phenotype and poor prognosis in hepatocellular carcinoma. | Decreased expression of SVEP1 is closely related to a cancer stem cell-like phenotype and poor prognosis in hepatocellular carcinoma.
Gong WC, Han ZQ, Guo MX, Zhao S, Guo YH, Meng B, Sun Y, Chen L. | 10/22/2022 |
| The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins alpha9beta1 and alpha4beta1. | The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.
Morris GE, Denniff MJ, Karamanavi E, Andrews SA, Kostogrys RB, Bountziouka V, Ghaderi-Najafabadi M, Shamkhi N, McConnell G, Kaiser MA, Carleton L, Schofield C, Kessler T, Rainbow RD, Samani NJ, Webb TR., Free PMC Article | 10/15/2022 |
| SVEP1 is important for morphogenesis of lymphatic system: Possible implications in lymphedema. | SVEP1 is important for morphogenesis of lymphatic system: Possible implications in lymphedema.
Michelini S, Amato B, Ricci M, Serrani R, Veselenyiova D, Kenanoglu S, Kurti D, Dautaj A, Baglivo M, Compagna R, Krajcovic J, Dundar M, Basha SH, Priya S, Belgrado JP, Bertelli M. | 04/2/2022 |
| A genome-wide association study identifying SVEP1 variant as a predictor of response to tolvaptan for cirrhotic ascites. | A genome-wide association study identifying SVEP1 variant as a predictor of response to tolvaptan for cirrhotic ascites.
Kawaratani H, Sawai H, Onishi M, Kogiso T, Shimada N, Uojima H, Nakajima T, Matsumoto N, Ikejima K, Ishikawa T, Terai S, Motoyama H, Komori A, Hirashima N, Saito S, Eguchi Y, Nojima M, Kawai Y, Tateyama M, Yoshiji H, Tanaka Y. | 03/12/2022 |
| Functional investigation of the coronary artery disease gene SVEP1. | Functional investigation of the coronary artery disease gene SVEP1.
Winkler MJ, Müller P, Sharifi AM, Wobst J, Winter H, Mokry M, Ma L, van der Laan SW, Pang S, Miritsch B, Hinterdobler J, Werner J, Stiller B, Güldener U, Webb TR, Asselbergs FW, Björkegren JLM, Maegdefessel L, Schunkert H, Sager HB, Kessler T., Free PMC Article | 10/23/2021 |
| SVEP1 is a human coronary artery disease locus that promotes atherosclerosis. | SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.
Jung IH, Elenbaas JS, Alisio A, Santana K, Young EP, Kang CJ, Kachroo P, Lavine KJ, Razani B, Mecham RP, Stitziel NO., Free PMC Article | 07/24/2021 |
| SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma. | SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma.
Young TL, Whisenhunt KN, Jin J, LaMartina SM, Martin SM, Souma T, Limviphuvadh V, Suri F, Souzeau E, Zhang X, Dan Y, Anagnos E, Carmona S, Jody NM, Stangel N, Higuchi EC, Huang SJ, Siggs OM, Simões MJ, Lawson BM, Martin JS, Elahi E, Narooie-Nejad M, Motlagh BF, Quaggin SE, Potter HD, Silva ED, Craig JE, Egas C, Maroofian R, Maurer-Stroh S, Bradfield YS, Tompson SW., Free PMC Article | 05/8/2021 |
| The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K/Akt pathway. | The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K/Akt pathway.
Chen L, Liu D, Yi X, Qi L, Tian X, Sun B, Dong Q, Han Z, Li Q, Song T, Guo M, Zhang W, Guo H, Zhang T., Free PMC Article | 04/13/2021 |
| increased polydom expression in the dermis surrounding neurofibromas may promote dermal neurofibroma development by activating TGF-beta1 | Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease.
Kamitani T, Murota H, Arase N, Wataya-Kaneda M, Sato-Nishiuchi R, Sekiguchi K, Okuzaki D, Motooka D, Katayama I. | 06/27/2020 |
| Downregulation of SVEP1 expression in primary keratinocytes resulted in decreased expression of major epidermal differentiation markers. | SVEP1 plays a crucial role in epidermal differentiation.
Samuelov L, Li Q, Bochner R, Najor NA, Albrecht L, Malchin N, Goldsmith T, Grafi-Cohen M, Vodo D, Fainberg G, Meilik B, Goldberg I, Warshauer E, Rogers T, Edie S, Ishida-Yamamoto A, Burzenski L, Erez N, Murray SA, Irvine AD, Shultz L, Green KJ, Uitto J, Sprecher E, Sarig O., Free PMC Article | 03/10/2018 |
| Top association findings suggested that the bipolar disorder risk allele at SNP rs7042161 in SVEP1 gene may be associated with increased risk of essential hypertension. | Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities.
Prieto ML, Ryu E, Jenkins GD, Batzler A, Nassan MM, Cuellar-Barboza AB, Pathak J, McElroy SL, Frye MA, Biernacka JM., Free PMC Article | 11/25/2017 |
| We also found significant associations between coronary artery disease and low-frequency missense variants in the genes SVEP1. | Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Stitziel NO, Stirrups KE, Masca NG, Erdmann J, Ferrario PG, König IR, Weeke PE, Webb TR, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kanoni S, Kruppa J, Mahajan A, Scott RA, Willenberg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer CM, El-Mokhtari NE, Franke A, Gottesman O, Heilmann S, Hengstenberg C, Hoffman P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Müller-Nurasyid M, Nikpay M, Olivieri O, Lemieux Perreault LP, AlQarawi A, Robertson NR, Akinsanya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Strauch K, Varga TV, Waldenberger M, Zeng L, Kraja AT, Liu C, Ehret GB, Newton-Cheh C, Chasman DI, Chowdhury R, Ferrario M, Ford I, Jukema JW, Kee F, Kuulasmaa K, Nordestgaard BG, Perola M, Saleheen D, Sattar N, Surendran P, Tregouet D, Young R, Howson JM, Butterworth AS, Danesh J, Ardissino D, Bottinger EP, Erbel R, Franks PW, Girelli D, Hall AS, Hovingh GK, Kastrati A, Lieb W, Meitinger T, Kraus WE, Shah SH, McPherson R, Orho-Melander M, Melander O, Metspalu A, Palmer CN, Peters A, Rader D, Reilly MP, Loos RJ, Reiner AP, Roden DM, Tardif JC, Thompson JR, Wareham NJ, Watkins H, Willer CJ, Kathiresan S, Deloukas P, Samani NJ, Schunkert H., Free PMC Article | 04/9/2016 |
| c.2080A>C SNP associated with increased 28-day mortality in septic shock | Identification of a nonsynonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock.
Nakada TA, Russell JA, Boyd JH, Thair SA, Walley KR. | 04/25/2015 |
| polydom is a hitherto unknown ligand for integrin alpha9beta1 that functions as a physiological ligand in vivo. | Polydom/SVEP1 is a ligand for integrin α9β1.
Sato-Nishiuchi R, Nakano I, Ozawa A, Sato Y, Takeichi M, Kiyozumi D, Yamazaki K, Yasunaga T, Futaki S, Sekiguchi K., Free PMC Article | 10/20/2012 |
| Increased UT-II, sTM, and vWF in ankylosing spondylitis patient sera regardless of treatment and disease activity suggest an increased tendency for atherosclerosis. | Evaluation of various endothelial biomarkers in ankylosing spondylitis.
Taylan A, Sari I, Kozaci DL, Yildiz Y, Bilge S, Coker I, Maltas S, Gunay N, Akkoc N. | 04/28/2012 |
| acts as regulator of ICAM1 and E-selectin during endotoxemia | Characterization of SVEP1, KIAA, and SRPX2 in an in vitro cell culture model of endotoxemia.
Schwanzer-Pfeiffer D, Rossmanith E, Schildberger A, Falkenhagen D. | 08/30/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Fine mapping of the 9q31 Hirschsprung's disease locus.
Tang CS, Sribudiani Y, Miao XP, de Vries AR, Burzynski G, So MT, Leon YY, Yip BH, Osinga J, Hui KJ, Verheij JB, Cherny SS, Tam PK, Sham PC, Hofstra RM, Garcia-Barceló MM., Free PMC Article | 06/30/2010 |
| All together makes SEL-OB/SVEP1 an attractive marker for studying the role of stromal osteogenic cells and their interactions within the bone marrow microenvironment creating a network that regulates the skeletal homeostasis. | Molecular and cellular characterization of SEL-OB/SVEP1 in osteogenic cells in vivo and in vitro.
Shur I, Socher R, Hameiri M, Fried A, Benayahu D. | 01/21/2010 |