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    MANF mesencephalic astrocyte derived neurotrophic factor [ Homo sapiens (human) ]

    Gene ID: 7873, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cerebrospinal fluid mesencephalic astrocyte-derived neurotrophic factor: A moderating effect on sleep time and cognitive function.

    Cerebrospinal fluid mesencephalic astrocyte-derived neurotrophic factor: A moderating effect on sleep time and cognitive function.
    Wang F, Han X, Mu Q, Chen H, Wu Y, Kang Y, Liu Y.

    08/3/2024
    Mesencephalic astrocyte-derived neurotrophic factor inhibits cervical cancer progression via regulating macrophage phenotype.

    Mesencephalic astrocyte-derived neurotrophic factor inhibits cervical cancer progression via regulating macrophage phenotype.
    Huang M, Hu J, Chen Y, Xun Y, Zhang X, Cao Y.

    07/8/2024
    MANF Promotes Unexplained Recurrent Miscarriages by Interacting with NPM1 and Downregulating Trophoblast Cell Migration and Invasion.

    MANF Promotes Unexplained Recurrent Miscarriages by Interacting with NPM1 and Downregulating Trophoblast Cell Migration and Invasion.
    Fang Y, Zhang J, Zhu D, Mei Q, Liao T, Cheng H, He Y, Cao Y, Wei Z., Free PMC Article

    06/26/2024
    MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects.

    MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects.
    Anttila JE, Mattila OS, Liew HK, Mätlik K, Mervaala E, Lindholm P, Lindahl M, Lindsberg PJ, Tseng KY, Airavaara M., Free PMC Article

    01/29/2024
    Deletion of mesencephalic astrocyte-derived neurotrophic factor delays and damages the development of white pulp in spleen.

    Deletion of mesencephalic astrocyte-derived neurotrophic factor delays and damages the development of white pulp in spleen.
    Zhou C, Han D, Fang H, Huang D, Cai H, Shen Y, Shen Y, Liu J.

    01/28/2024
    Serum levels of interleukin-33 and mesencephalic astrocyte derived neurotrophic factors in patients with major depressive disorder: a cross-sectional comparative design.

    Serum levels of interleukin-33 and mesencephalic astrocyte derived neurotrophic factors in patients with major depressive disorder: a cross-sectional comparative design.
    Nahar Z, Nowshin DT, Roknuzzaman ASM, Sohan M, Islam S, Qusar MMAS, Islam MR., Free PMC Article

    01/27/2024
    MANF inhibits Sjogren's syndrome salivary gland epithelial cell apoptosis and antigen expression of Ro52/SSA through endoplasmic reticulum stress/autophagy pathway.

    MANF inhibits Sjögren's syndrome salivary gland epithelial cell apoptosis and antigen expression of Ro52/SSA through endoplasmic reticulum stress/autophagy pathway.
    Cheng D, Zhou T, Liu H, Li L, Xuan Y, Huang L, Liu Y, Zhang X, Wei W, Wu H.

    08/28/2023
    Prognostic potential of serum mesencephalic astrocyte-derived neurotrophic factor in acute intracerebral hemorrhage: a prospective observational study.

    Prognostic potential of serum mesencephalic astrocyte-derived neurotrophic factor in acute intracerebral hemorrhage: a prospective observational study.
    Zhang CL, Fang LL, Wang CL, Li P, Yang M, Xu JW., Free PMC Article

    06/16/2023
    A prospective observational study on utility of serum mesencephalic astrocyte-derived neurotrophic factor as a promising prognostic biomarker of severe traumatic brain injury in humans.

    A prospective observational study on utility of serum mesencephalic astrocyte-derived neurotrophic factor as a promising prognostic biomarker of severe traumatic brain injury in humans.
    Wang KW, Zhan CP, Liu YQ, Fu ZZ, Qiu TW, Yu GF.

    06/2/2023
    Mesencephalic astrocyte-derived neurotrophic factor (MANF) prevents the neuroinflammation induced dopaminergic neurodegeneration.

    Mesencephalic astrocyte-derived neurotrophic factor (MANF) prevents the neuroinflammation induced dopaminergic neurodegeneration.
    Zhang JX, Zhou KG, Yin YX, Jin LJ, Tong WF, Guo J, Yu LH, Ye XC, Jiang M.

    01/7/2023
    MANF Inhibits alpha-Synuclein Accumulation through Activation of Autophagic Pathways.

    MANF Inhibits α-Synuclein Accumulation through Activation of Autophagic Pathways.
    Zhang JX, Tong WF, Jiang M, Zhou KG, Xiang XR, He YJ, Zhang ZY, Guan Q, Jin LJ., Free PMC Article

    07/23/2022
    Mesencephalic astrocyte-derived neurotrophic factor attenuates acute lung injury via inhibiting macrophages' activation.

    Mesencephalic astrocyte-derived neurotrophic factor attenuates acute lung injury via inhibiting macrophages' activation.
    Shen QY, Wang D, Xu HY, Wei CS, Xiao XY, Liu J, Shen YJ, Fang L, Feng LJ, Shen YX.

    06/18/2022
    Mesencephalic astrocyte-derived neurotrophic factor reprograms macrophages to ameliorate acetaminophen-induced acute liver injury via p38 MAPK pathway.

    Mesencephalic astrocyte-derived neurotrophic factor reprograms macrophages to ameliorate acetaminophen-induced acute liver injury via p38 MAPK pathway.
    Hou X, Liu Q, Gao Y, Yong L, Xie H, Li W, Zhou Y, Liu J, Feng L, Xu L, Shen Y, Wang H., Free PMC Article

    03/26/2022
    The relationship of mesencephalic astrocyte-derived neurotrophic factor with hyperlipidemia in patients with or without type 2 diabetes mellitus.

    The relationship of mesencephalic astrocyte-derived neurotrophic factor with hyperlipidemia in patients with or without type 2 diabetes mellitus.
    Fu J, Malale K, Luo X, Chen M, Liu Q, Cheng W, Liu D.

    03/5/2022
    Correlation of Significantly Decreased Serum Circulating Mesencephalic Astrocyte-Derived Neurotrophic Factor Level With an Increased Risk of Future Cardiovascular Disease in Adult Patients With Growth Hormone Deficiency.

    Correlation of Significantly Decreased Serum Circulating Mesencephalic Astrocyte-Derived Neurotrophic Factor Level With an Increased Risk of Future Cardiovascular Disease in Adult Patients With Growth Hormone Deficiency.
    Ren Z, Wang Y, Chen Q, Long J, Zhang R, Wu X, Qian W, Chen Y, Liu D, Ren W., Free PMC Article

    12/25/2021
    Analysis of Mesencephalic Astrocyte-derived Neurotrophic Factor in Multiple Myeloma.

    Analysis of Mesencephalic Astrocyte-derived Neurotrophic Factor in Multiple Myeloma.
    Dernoncourt A, Sauzay C, Schmidt J, Louandre C, Gomila C, Duhaut P, Herpe YE, Saidak Z, Galmiche A, Salle V.

    09/18/2021
    The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor.

    The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor.
    Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M., Free PMC Article

    09/4/2021
    Decreased Plasma MANF Levels are Associated with Type 2 Diabetes.

    Decreased Plasma MANF Levels are Associated with Type 2 Diabetes.
    Wang C, Peng JJ, Miao H, Liu DF, Zhang LL.

    08/7/2021
    Mesencephalic astrocyte-derived neurotrophic factor: A treatment option for parkinson's disease.

    Mesencephalic astrocyte-derived neurotrophic factor: A treatment option for parkinson's disease.
    Yang C, Gao Y.

    06/12/2021
    Hepatocyte-derived MANF alleviates hepatic ischaemia-reperfusion injury via regulating endoplasmic reticulum stress-induced apoptosis in mice.

    Hepatocyte-derived MANF alleviates hepatic ischaemia-reperfusion injury via regulating endoplasmic reticulum stress-induced apoptosis in mice.
    Yang Y, Wang P, Zhang C, Huang F, Pang G, Wei C, Lv C, Chhetri G, Jiang T, Liu J, Shen Y, Shen Y.

    05/29/2021
    Mesencephalic Astrocyte-Derived Neurotrophic Factor Inhibits Liver Cancer Through Small Ubiquitin-Related Modifier (SUMO)ylation-Related Suppression of NF-kappaB/Snail Signaling Pathway and Epithelial-Mesenchymal Transition.

    Mesencephalic Astrocyte-Derived Neurotrophic Factor Inhibits Liver Cancer Through Small Ubiquitin-Related Modifier (SUMO)ylation-Related Suppression of NF-κB/Snail Signaling Pathway and Epithelial-Mesenchymal Transition.
    Liu J, Wu Z, Han D, Wei C, Liang Y, Jiang T, Chen L, Sha M, Cao Y, Huang F, Geng X, Yu J, Shen Y, Wang H, Feng L, Wang D, Fang S, Wang S, Shen Y., Free PMC Article

    04/17/2021
    Diagnostic and Prognostic Values of MANF Expression in Hepatocellular Carcinoma.

    Diagnostic and Prognostic Values of MANF Expression in Hepatocellular Carcinoma.
    He J, Li G, Liu X, Ma L, Zhang P, Zhang J, Zheng S, Wang J, Liu J., Free PMC Article

    02/13/2021
    Effects of mesencephalic astrocyte-derived neurotrophic factor on cerebral angiogenesis in a rat model of cerebral ischemia.

    Effects of mesencephalic astrocyte-derived neurotrophic factor on cerebral angiogenesis in a rat model of cerebral ischemia.
    Gao B, Deng J, Zhang X, Sun H, Jia G, Li J, Zhang K, Wan C, Wang L, Yan LJ, Cai Z, Ma J.

    01/9/2021
    Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice.

    Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice.
    Galli E, Rossi J, Neumann T, Andressoo JO, Drinda S, Lindholm P., Free PMC Article

    11/21/2020
    Circulating Mesencephalic Astrocyte-Derived Neurotrophic Factor Negatively Correlates With Atrial Apoptosis in Human Chronic Atrial Fibrillation.

    Circulating Mesencephalic Astrocyte-Derived Neurotrophic Factor Negatively Correlates With Atrial Apoptosis in Human Chronic Atrial Fibrillation.
    Wang C, Yu S, Bao Q, Qiang W, Wu C, Zhang C, Jiang Y, Cai Y, Huang D, Chen Y, Hou C, Wang D.

    10/3/2020
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