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    ZFP36 ZFP36 ring finger protein [ Homo sapiens (human) ]

    Gene ID: 7538, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Persistent infection with Porphyromonas gingivalis increases the tumorigenic potential of human immortalised oral epithelial cells through ZFP36 inhibition.

    Persistent infection with Porphyromonas gingivalis increases the tumorigenic potential of human immortalised oral epithelial cells through ZFP36 inhibition.
    Lu Z, Cao R, Geng F, Pan Y., Free PMC Article

    06/13/2024
    ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNbeta/lambda expression and promotes ZIKV persistence.

    ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNβ/λ expression and promotes ZIKV persistence.
    Schutt WR, Conde JN, Mladinich MC, Himmler GE, Mackow ER., Free PMC Article

    01/3/2024
    ZFP36 loss-mediated BARX1 stabilization promotes malignant phenotypes by transactivating master oncogenes in NSCLC.

    ZFP36 loss-mediated BARX1 stabilization promotes malignant phenotypes by transactivating master oncogenes in NSCLC.
    Zhang T, Qiu L, Cao J, Li Q, Zhang L, An G, Ni J, Jia H, Li S, Li K., Free PMC Article

    08/19/2023
    Silencing lncRNA CDKN2B-AS1 Alleviates Childhood Asthma Progression Through Inhibiting ZFP36 Promoter Methylation and Promoting NR4A1 Expression.

    Silencing lncRNA CDKN2B-AS1 Alleviates Childhood Asthma Progression Through Inhibiting ZFP36 Promoter Methylation and Promoting NR4A1 Expression.
    Chen Z, Fan N, Shen G, Yang J.

    03/24/2023
    Assessing the expression of two post-transcriptional BDNF regulators, TTP and miR-16 in the peripheral blood of patients with Schizophrenia.

    Assessing the expression of two post-transcriptional BDNF regulators, TTP and miR-16 in the peripheral blood of patients with Schizophrenia.
    Asadi MR, Gharesouran J, Sabaie H, Moslehian MS, Dehghani H, Arsang-Jang S, Taheri M, Mortazavi D, Hussen BM, Sayad A, Rezazadeh M., Free PMC Article

    12/17/2022
    Intrinsically disordered regions of tristetraprolin and DCP2 directly interact to mediate decay of ARE-mRNA.

    Intrinsically disordered regions of tristetraprolin and DCP2 directly interact to mediate decay of ARE-mRNA.
    Maciej VD, Mateva N, Schwarz J, Dittmers T, Mallick M, Urlaub H, Chakrabarti S., Free PMC Article

    10/22/2022
    Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification.

    Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification.
    Lyu F, Li Y, Yan Z, He Q, Cheng L, Zhang P, Liu B, Liu C, Song Y, Xing Y., Free PMC Article

    05/14/2022
    Tristetraprolin Prevents Gastric Metaplasia in Mice by Suppressing Pathogenic Inflammation.

    Tristetraprolin Prevents Gastric Metaplasia in Mice by Suppressing Pathogenic Inflammation.
    Busada JT, Khadka S, Peterson KN, Druffner SR, Stumpo DJ, Zhou L, Oakley RH, Cidlowski JA, Blackshear PJ., Free PMC Article

    04/2/2022
    TTP-mediated regulation of mRNA stability in immune cells contributes to adaptive immunity, immune tolerance and clinical applications.

    TTP-mediated regulation of mRNA stability in immune cells contributes to adaptive immunity, immune tolerance and clinical applications.
    Zhang Y, Zhou J, Wei Z, Dong H, Yang D, Deng Y, Li J, Shi S, Sun Y, Lu H, Yuan J, Ni B, Wu Y, Tian Y, Han C., Free PMC Article

    03/5/2022
    ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells.

    ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells.
    Wang X, Ge X, Liao W, Cao Y, Li R, Zhang F, Zhao B, Du J., Free PMC Article

    02/26/2022
    LINC00998 functions as a novel tumor suppressor in acute myeloid leukemia via regulating the ZFP36 ring finger protein/mammalian target of rapamycin complex 2 axis.

    LINC00998 functions as a novel tumor suppressor in acute myeloid leukemia via regulating the ZFP36 ring finger protein/mammalian target of rapamycin complex 2 axis.
    Fang X, Pan X, Mai H, Yuan X, Liu S, Wen F., Free PMC Article

    02/19/2022
    ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.

    ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.
    Angiolilli C, Leijten EFA, Bekker CPJ, Eeftink E, Giovannone B, Nordkamp MO, van der Wal M, Thijs JL, Vastert SJ, van Wijk F, Radstake TRDJ, van Loosdregt J.

    02/5/2022
    Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy.

    Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy.
    Dolicka D, Sobolewski C, Gjorgjieva M, Correia de Sousa M, Berthou F, De Vito C, Colin DJ, Bejuy O, Fournier M, Maeder C, Blackshear PJ, Rubbia-Brandt L, Foti M., Free PMC Article

    12/25/2021
    Cataloguing the phosphorylation sites of tristetraprolin (TTP): Functional implications for inflammatory diseases.

    Cataloguing the phosphorylation sites of tristetraprolin (TTP): Functional implications for inflammatory diseases.
    Rezcallah MC, Al-Mazi T, Ammit AJ.

    12/11/2021
    LncRNA DLEU2 promotes cervical cancer cell proliferation by regulating cell cycle and NOTCH pathway.

    LncRNA DLEU2 promotes cervical cancer cell proliferation by regulating cell cycle and NOTCH pathway.
    He M, Wang Y, Cai J, Xie Y, Tao C, Jiang Y, Li H, Song F.

    09/25/2021
    Tristetraprolin: A cytosolic regulator of mRNA turnover moonlighting as transcriptional corepressor of gene expression.

    Tristetraprolin: A cytosolic regulator of mRNA turnover moonlighting as transcriptional corepressor of gene expression.
    Rodríguez-Gómez G, Paredes-Villa A, Cervantes-Badillo MG, Gómez-Sonora JP, Jorge-Pérez JH, Cervantes-Roldán R, León-Del-Río A.

    09/11/2021
    Identification of an AP1-ZFP36 Regulatory Network Associated with Breast Cancer Prognosis.

    Identification of an AP1-ZFP36 Regulatory Network Associated with Breast Cancer Prognosis.
    Canzoneri R, Naipauer J, Stedile M, Rodriguez Peña A, Lacunza E, Gandini NA, Curino AC, Facchinetti MM, Coso OA, Kordon E, Abba MC.

    06/5/2021
    SIRT3, PP2A and TTP protein stability in the presence of TNF-alpha on vincristine-induced apoptosis of leukaemia cells.

    SIRT3, PP2A and TTP protein stability in the presence of TNF-α on vincristine-induced apoptosis of leukaemia cells.
    Wang LJ, Chiou JT, Lee YC, Huang CH, Shi YJ, Chang LS., Free PMC Article

    05/1/2021
    Tristetraprolin Posttranscriptionally Downregulates TRAIL Death Receptors.

    Tristetraprolin Posttranscriptionally Downregulates TRAIL Death Receptors.
    Lee WH, Han MW, Kim SH, Seong D, An JH, Chang HW, Kim SY, Kim SW, Lee JC., Free PMC Article

    03/28/2021
    Circular RNA 000554 represses epithelial-mesenchymal transition in breast cancer by regulating microRNA-182/ZFP36 axis.

    Circular RNA 000554 represses epithelial-mesenchymal transition in breast cancer by regulating microRNA-182/ZFP36 axis.
    Mao Y, Lv M, Cao W, Liu X, Cui J, Wang Y, Wang Y, Nie G, Liu X, Wang H.

    03/27/2021
    RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease.

    RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease.
    Guo J, Lei M, Cheng F, Liu Y, Zhou M, Zheng W, Zhou Y, Gong R, Liu Z., Free PMC Article

    03/20/2021
    Wnt/CTNNB1 Signal Transduction Pathway Inhibits the Expression of ZFP36 in Squamous Cell Carcinoma, by Inducing Transcriptional Repressors SNAI1, SLUG and TWIST.

    Wnt/CTNNB1 Signal Transduction Pathway Inhibits the Expression of ZFP36 in Squamous Cell Carcinoma, by Inducing Transcriptional Repressors SNAI1, SLUG and TWIST.
    Zanfi ED, Fantini S, Lotti R, Bertesi M, Marconi A, Grande A, Manfredini R, Pincelli C, Zanocco-Marani T., Free PMC Article

    02/20/2021
    A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells.

    A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells.
    Lee S, Micalizzi D, Truesdell SS, Bukhari SIA, Boukhali M, Lombardi-Story J, Kato Y, Choo MK, Dey-Guha I, Ji F, Nicholson BT, Myers DT, Lee D, Mazzola MA, Raheja R, Langenbucher A, Haradhvala NJ, Lawrence MS, Gandhi R, Tiedje C, Diaz-Muñoz MD, Sweetser DA, Sadreyev R, Sykes D, Haas W, Haber DA, Maheswaran S, Vasudevan S., Free PMC Article

    01/9/2021
    TTP may contribute to suppression of glycolysis and energy production of cancer cells in part by downregulating PFKFB3 expression.

    Tristetraprolin posttranscriptionally downregulates PFKFB3 in cancer cells.
    Jang JH, Kim DJ, Ham SY, Vo MT, Jeong SY, Choi SH, Park SS, Jeon DY, Lee BJ, Ko BK, Cho WJ, Park JW.

    08/1/2020
    ZFP36 regulates the processing of the HLA-DQ mRNAs.

    Tristetraprolin/ZFP36 Regulates the Turnover of Autoimmune-Associated HLA-DQ mRNAs.
    Pisapia L, Hamilton RS, Farina F, D'Agostino V, Barba P, Strazzullo M, Provenzani A, Gianfrani C, Del Pozzo G., Free PMC Article

    08/1/2020
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