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    YY1 YY1 transcription factor [ Homo sapiens (human) ]

    Gene ID: 7528, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Transcription factor YY1-activated GNG5 facilitates glioblastoma cell growth, invasion, stemness and glycolysis through Wnt/beta-catenin pathway.

    Transcription factor YY1-activated GNG5 facilitates glioblastoma cell growth, invasion, stemness and glycolysis through Wnt/β-catenin pathway.
    Liang S, Zhu L, Yang F, Dong H., Free PMC Article

    10/25/2024
    DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.

    DEAD/H-box helicase 11 is transcriptionally activated by Yin Yang-1 and accelerates oral squamous cell carcinoma progression.
    Yang G, Shi X, Zhang M, Wang K, Tian X, Wang X.

    10/16/2024
    ENAH transcriptionally activated by YY1 promotes growth and invasion of laryngocarcinoma cells through PI3K/AKT signaling.

    ENAH transcriptionally activated by YY1 promotes growth and invasion of laryngocarcinoma cells through PI3K/AKT signaling.
    Yin X, Wang J, Shen Z, Jia Q, Bian Y, Yang Z, Liu Y, Li Y, Zhang H.

    10/15/2024
    The YY1-CPT1C signaling axis modulates the proliferation and metabolism of pancreatic tumor cells under hypoxia.

    The YY1-CPT1C signaling axis modulates the proliferation and metabolism of pancreatic tumor cells under hypoxia.
    Zhou Y, Chen Y, Zhao P, Xian T, Gao Y, Fan S, Fang JH, Huang M, Bi H.

    09/26/2024
    The Role of PTEN in Chemoresistance Mediated by the HIF-1alpha/YY1 Axis in Pediatric Acute Lymphoblastic Leukemia.

    The Role of PTEN in Chemoresistance Mediated by the HIF-1α/YY1 Axis in Pediatric Acute Lymphoblastic Leukemia.
    Antonio-Andres G, Morales-Martinez M, Jimenez-Hernandez E, Huerta-Yepez S., Free PMC Article

    09/3/2024
    Transcription Factor yin-Yang 1 augments nucleoporin 93 oncogene activity and modulates bladder Cancer malignancy.

    Transcription Factor yin-Yang 1 augments nucleoporin 93 oncogene activity and modulates bladder Cancer malignancy.
    Zhang G, Wei W, Li S, Yang J.

    08/21/2024
    YY1 is involved in homologous recombination inhibition at guanine quadruplex sites in human cells.

    YY1 is involved in homologous recombination inhibition at guanine quadruplex sites in human cells.
    Cui X, Zhang C, Fu C, Hu J, Li T, Li L., Free PMC Article

    08/20/2024
    YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway.

    YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway.
    Shen Y, Yang Y, Zhao Y, Nuerlan S, Zhan Y, Liu C., Free PMC Article

    07/11/2024
    Lnc-PIK3R1, transcriptionally suppressed by YY1, inhibits hepatocellular carcinoma progression via the Lnc-PIK3R1/miR-1286/GSK3beta axis.

    Lnc-PIK3R1, transcriptionally suppressed by YY1, inhibits hepatocellular carcinoma progression via the Lnc-PIK3R1/miR-1286/GSK3β axis.
    Lyu P, Li F, Deng R, Wei Q, Lin B, Cheng L, Zhao B, Lu Z.

    07/1/2024
    YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway.

    YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway.
    Lin Y, Li Y, Chen X, Jin X, Jiang M, Xiao H, Chen L, Chen M, Zhang W, Chen H, Nie Q, Guo R, Guo W, Fu F, Wang C., Free PMC Article

    06/12/2024
    YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.

    YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
    Huang J, Wang X, Li N, Fan W, Li X, Zhou Q, Liu J, Li W, Zhang Z, Liu X, Zeng S, Yang H, Tian M, Yang P, Hou S., Free PMC Article

    06/7/2024
    A mutual regulatory loop between transcription factor Yin Yang 1 and hepatitis B virus replication influences chronic hepatitis B.

    A mutual regulatory loop between transcription factor Yin Yang 1 and hepatitis B virus replication influences chronic hepatitis B.
    Zhou J, Hua Y, Liu Y, Wu T, Xu H, Wang Z, Wang X, Niu J.

    05/24/2024
    The DDX6/KIFC1 signaling axis, as regulated by YY1, contributes to the malignant behavior of pancreatic cancer.

    The DDX6/KIFC1 signaling axis, as regulated by YY1, contributes to the malignant behavior of pancreatic cancer.
    Deng X, Liu Z, Wang B, Ma J, Meng X.

    04/5/2024
    RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter.

    RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter.
    Wu H, Xia L, Sun L, Li D, Liu X, Song H, Sheng J, Wang K, Feng Q., Free PMC Article

    03/26/2024
    Yin Yang 1 suppresses apoptosis and oxidative stress injury in SH-SY5Y cells by facilitating NR4A1 expression.

    Yin Yang 1 suppresses apoptosis and oxidative stress injury in SH-SY5Y cells by facilitating NR4A1 expression.
    Kang Q, Chai W, Min J, Qu X.

    03/15/2024
    SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis.

    SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis.
    Li X, Tao S, Xu Z, Ren Y, Xiang W, He X.

    03/13/2024
    MiR-192-5p Ameliorates Hepatic Lipid Metabolism in Non-Alcoholic Fatty Liver Disease by Targeting Yy1.

    MiR-192-5p Ameliorates Hepatic Lipid Metabolism in Non-Alcoholic Fatty Liver Disease by Targeting Yy1.
    Ma L, Song H, Zhang CY, Hou D., Free PMC Article

    02/12/2024
    Clinical analysis of Gabriele-de Vries caused by YY1 mutations and literature review.

    Clinical analysis of Gabriele-de Vries caused by YY1 mutations and literature review.
    Yang J, Yu C, Lyn N, Liu L, Li D, Shang Q., Free PMC Article

    02/7/2024
    YY1 modulates the radiosensitivity of esophageal squamous cell carcinoma through KIF3B-mediated Hippo signaling pathway.

    YY1 modulates the radiosensitivity of esophageal squamous cell carcinoma through KIF3B-mediated Hippo signaling pathway.
    Zheng C, Li Z, Zhao C, Yin X, Feng L, Wang Z, Liu C, Li B., Free PMC Article

    01/16/2024
    BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.

    BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.
    Duan B, Zhou X, Zhang X, Qiu F, Zhang S, Chen Y, Yang J, Wang J, Tan W.

    12/6/2023
    Epigenetic regulation of enhancer of zeste homolog 2 (EZH2) -Yin Yang 1 (YY1) axis in cancer.

    Epigenetic regulation of enhancer of zeste homolog 2 (EZH2) -Yin Yang 1 (YY1) axis in cancer.
    Chandnani N, Gupta I, Thakkar V, Sarkar K.

    11/14/2023
    YY1-regulated lncRNA SOCS2-AS1 suppresses HCC cell stemness and progression via miR-454-3p/CPEB1.

    YY1-regulated lncRNA SOCS2-AS1 suppresses HCC cell stemness and progression via miR-454-3p/CPEB1.
    Zhong F, Wang Y.

    11/13/2023
    METTL3 facilitates multiple myeloma tumorigenesis by enhancing YY1 stability and pri-microRNA-27 maturation in m[6]A-dependent manner.

    METTL3 facilitates multiple myeloma tumorigenesis by enhancing YY1 stability and pri-microRNA-27 maturation in m(6)A-dependent manner.
    Che F, Ye X, Wang Y, Wang X, Ma S, Tan Y, Mao Y, Luo Z.

    10/8/2023
    Binding of YY1/CREB to an Enhancer Region Triggers Claudin 6 Expression in H. pylori LPS-Stimulated AGS Cells.

    Binding of YY1/CREB to an Enhancer Region Triggers Claudin 6 Expression in H. pylori LPS-Stimulated AGS Cells.
    Romero-Estrada JH, Montaño LF, Rendón-Huerta EP., Free PMC Article

    09/30/2023
    YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.

    YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.
    Zhang C, Chen S, Wang W, Gao Y.

    08/9/2023
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