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    CCR2 C-C motif chemokine receptor 2 [ Homo sapiens (human) ]

    Gene ID: 729230, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Chemokine CCL2 and its receptor CCR2 in different age groups of patients with COVID-19.

    Chemokine CCL2 and its receptor CCR2 in different age groups of patients with COVID-19.
    Bagheri V, Khorramdelazad H, Kafi M, Abbasifard M., Free PMC Article

    10/31/2024
    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow.

    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow.
    Hurwitz SN, Kobulsky DR, Jung SK, Chia JJ, Butler JM, Kurre P., Free PMC Article

    09/25/2024
    The novel potential therapeutic target PSMP/MSMP promotes acute kidney injury via CCR2.

    The novel potential therapeutic target PSMP/MSMP promotes acute kidney injury via CCR2.
    Song Z, Yao W, Wang X, Mo Y, Liu Z, Li Q, Jiang L, Wang H, He H, Li N, Zhang Z, Lv P, Zhang Y, Yang L, Wang Y.,

    07/29/2024
    Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway.

    Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway.
    Tian S, Chen X, Wu W, Lin H, Qing X, Liu S, Wang B, Xiao Y, Shao Z, Peng Y., Free PMC Article

    03/6/2024
    [Expression of MCP-1 and CCR2 in Newly Diagnosed Diffuse Large B-Cell Lymphoma and Clinical Significance].

    [Expression of MCP-1 and CCR2 in Newly Diagnosed Diffuse Large B-Cell Lymphoma and Clinical Significance].
    Wang M, Zhang PP, Zhu Q, Hu ZL, Bai X, Wu YP, Li JJ.

    02/27/2024
    CCR2 is a potential therapeutic target in peri-implantitis.

    CCR2 is a potential therapeutic target in peri-implantitis.
    Yuan S, Wei Y, Jiang W, Sun F, Li S, Li Q, Song Z, Liu Z, Mo Y, Wang X, Li N, Lv P, She S, Wang C, Zhang Y, Wang Y, Hu W.

    02/22/2024
    Human inherited CCR2 deficiency underlies progressive polycystic lung disease.

    Human inherited CCR2 deficiency underlies progressive polycystic lung disease.
    Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, Corcini Berndt M, Rinchai D, Le Voyer T, Rosain J, Momenilandi M, Martin-Fernandez M, Khan T, Bohlen J, Han JE, Deslys A, Bernard M, Gajardo-Carrasco T, Soudée C, Le Floc'h C, Migaud M, Seeleuthner Y, Jang MS, Nikolouli E, Seyedpour S, Begueret H, Emile JF, Le Guen P, Tavazzi G, Colombo CNJ, Marzani FC, Angelini M, Trespidi F, Ghirardello S, Alipour N, Molitor A, Carapito R, Mazloomrezaei M, Rokni-Zadeh H, Changi-Ashtiani M, Brouzes C, Vargas P, Borghesi A, Lachmann N, Bahram S, Crestani B, Fayon M, Galode F, Pahari S, Schlesinger LS, Marr N, Bogunovic D, Boisson-Dupuis S, Béziat V, Abel L, Borie R, Young LR, Deterding R, Shahrooei M, Rezaei N, Parvaneh N, Craven D, Gros P, Malo D, Sepulveda FE, Nogee LM, Aladjidi N, Trapnell BC, Casanova JL, Bustamante J., Free PMC Article

    01/29/2024
    C5a enhances Vdelta1 T cells recruitment via the CCL2-CCR2 axis in IgA nephropathy.

    C5a enhances Vδ1 T cells recruitment via the CCL2-CCR2 axis in IgA nephropathy.
    Deng S, Zhou F, Wang F, Jiang Y, Tang J, Hu X, Luo L, Jin Y, Huang L, Sun D, Xiao G, Feng J, Li X.

    11/30/2023
    Role of MCP-1/CCR2 axis in renal fibrosis: Mechanisms and therapeutic targeting.

    Role of MCP-1/CCR2 axis in renal fibrosis: Mechanisms and therapeutic targeting.
    He S, Yao L, Li J., Free PMC Article

    10/30/2023
    The CCL2-CCR2 Axis Contributes to Migration of Cabazitaxel-resistant Prostate Cancer Cells.

    The CCL2-CCR2 Axis Contributes to Migration of Cabazitaxel-resistant Prostate Cancer Cells.
    Natsagdorj A, Izumi K, Hiratsuka K, Naito R, Kadomoto S, Iwamoto H, Yaegashi H, Shigehara K, Nakata H, Mizokami A.

    10/20/2023
    Association between CCR2 and CCL2 expression and NET stimulation in adult-onset Still's disease.

    Association between CCR2 and CCL2 expression and NET stimulation in adult-onset Still's disease.
    Jung JY, Ahn MH, Kim JW, Suh CH, Han JH, Kim HA., Free PMC Article

    08/2/2023
    Significant association of MCP1 rs1024611 and CCR2 rs1799864 polymorphisms with colorectal cancer and liver metastases susceptibility and aggressiveness: A case-control study.

    Significant association of MCP1 rs1024611 and CCR2 rs1799864 polymorphisms with colorectal cancer and liver metastases susceptibility and aggressiveness: A case-control study.
    Boughriba R, Sahraoui G, Chaar I, Weslati M, Ayed K, Ounissi D, Hazgui M, Bouraoui S, Gati A.

    06/13/2023
    C-C motif chemokine receptor 2 inhibition reduces liver fibrosis by restoring the immune cell landscape.

    C-C motif chemokine receptor 2 inhibition reduces liver fibrosis by restoring the immune cell landscape.
    Guo Y, Zhao C, Dai W, Wang B, Lai E, Xiao Y, Tang C, Huang Z, Gao J., Free PMC Article

    05/30/2023
    Role of chemokine receptor 2 in rheumatoid arthritis: A research update.

    Role of chemokine receptor 2 in rheumatoid arthritis: A research update.
    Chen W, Fang Y, Wang H, Tan X, Zhu X, Xu Z, Jiang H, Wu X, Hong W, Wang X, Tu J, Wei W.

    03/13/2023
    The impact of MCP1-2518A/G and CCR2-V64I genetic polymorphisms in Egyptian sickle cell disease patients.

    The impact of MCP1-2518A/G and CCR2-V64I genetic polymorphisms in Egyptian sickle cell disease patients.
    Ibrahim NS, Makhlouf MM, Shahin GH, Elghamrawy MK, Hussein NM.

    10/29/2022
    LPS differentially affects expression of CD14 and CCR2 in monocyte subsets of Post-STEMI patients with hyperglycemia.

    LPS differentially affects expression of CD14 and CCR2 in monocyte subsets of Post-STEMI patients with hyperglycemia.
    Blanks AM, Pedersen LN, Caslin HL, Mihalick VL, Via J, Canada JM, Van Tassell B, Carbone S, Abbate A, Lee Franco R.

    10/8/2022
    Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications.

    Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications.
    Zhang H, Yang K, Chen F, Liu Q, Ni J, Cao W, Hua Y, He F, Liu Z, Li L, Fan G., Free PMC Article

    10/1/2022
    CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis.

    CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis.
    Zoshima T, Baba T, Tanabe Y, Ishida Y, Nakatani K, Nagata M, Mukaida N, Kawano M.

    07/16/2022
    Chemokine (C-C motif) receptor 2 is associated with the pathological grade and inflammatory response in IgAN children.

    Chemokine (C-C motif) receptor 2 is associated with the pathological grade and inflammatory response in IgAN children.
    Shen Y, Zhu Z, Wang R, Yan L, Sun S, Lu L, Ren Z, Zhang Q., Free PMC Article

    06/25/2022
    Targeting the CCL2-CCR2 axis for atheroprotection.

    Targeting the CCL2-CCR2 axis for atheroprotection.
    Georgakis MK, Bernhagen J, Heitman LH, Weber C, Dichgans M.

    05/28/2022
    Functional Roles of Chemokine Receptor CCR2 and Its Ligands in Liver Disease.

    Functional Roles of Chemokine Receptor CCR2 and Its Ligands in Liver Disease.
    She S, Ren L, Chen P, Wang M, Chen D, Wang Y, Chen H., Free PMC Article

    05/7/2022
    Sex differences in monocyte CCR2 expression and macrophage polarization following acute exercise.

    Sex differences in monocyte CCR2 expression and macrophage polarization following acute exercise.
    Blanks AM, Pedersen LN, Bohmke N, Mihalick VL, Franco RL.

    05/7/2022
    Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2.

    Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2.
    Mysore V, Tahir S, Furuhashi K, Arora J, Rosetti F, Cullere X, Yazbeck P, Sekulic M, Lemieux ME, Raychaudhuri S, Horwitz BH, Mayadas TN., Free PMC Article

    04/30/2022
    Role of Distinct Macrophage Populations in the Development of Heart Failure in Macrophage Activation Syndrome.

    Role of Distinct Macrophage Populations in the Development of Heart Failure in Macrophage Activation Syndrome.
    Kuna J, Żuber Z, Chmielewski G, Gromadziński L, Krajewska-Włodarczyk M., Free PMC Article

    04/2/2022
    CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender.

    CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender.
    Sharif-Zak M, Abbasi-Jorjandi M, Asadikaram G, Ghoreshi ZA, Rezazadeh-Jabalbarzi M, Afsharipur A, Rashidinejad H, Khajepour F, Jafarzadeh A, Arefinia N, Kheyrkhah A, Abolhassani M., Free PMC Article

    03/19/2022
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