| LncRNA BRE-AS1 regulates the JAK2/STAT3-mediated inflammatory activation via the miR-30b-5p/SOC3 axis in THP-1 cells. | LncRNA BRE-AS1 regulates the JAK2/STAT3-mediated inflammatory activation via the miR-30b-5p/SOC3 axis in THP-1 cells.
Shin JJ, Suk K, Lee WH., Free PMC Article | 11/7/2024 |
| GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3. | GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
Chen Z, Xu L, Lin S, Huang H, Long Q, Liu J., Free PMC Article | 11/7/2024 |
| STAT1 and STAT3 gain of function: clinically heterogenous immune regulatory disorders. | STAT1 and STAT3 gain of function: clinically heterogenous immune regulatory disorders.
Olbrich P, Freeman AF., Free PMC Article | 11/7/2024 |
| The PTPRZ1-MET/STAT3/ISG20 axis in glioma stem-like cells modulates tumor-associated macrophage polarization. | The PTPRZ1-MET/STAT3/ISG20 axis in glioma stem-like cells modulates tumor-associated macrophage polarization.
Wang Y, Suo J, Wang Z, Ran K, Tian Y, Han W, Liu Y, Peng X. | 11/5/2024 |
| The STAT3/SETDB2 axis dictates NF-kappaB-mediated inflammation in macrophages during wound repair. | The STAT3/SETDB2 axis dictates NF-κB-mediated inflammation in macrophages during wound repair.
Mangum KD, denDekker A, Li Q, Tsoi LC, Joshi AD, Melvin WJ, Wolf SJ, Moon JY, Audu CO, Shadiow J, Obi AT, Wasikowski R, Barrett EC, Bauer TM, Boyer K, Ahmed Z, Davis FM, Gudjonsson J, Gallagher KA., Free PMC Article | 10/30/2024 |
| Unraveling the unphosphorylated STAT3-unphosphorylated NF-kappaB pathway in loss of function STAT3 Hyper IgE syndrome. | Unraveling the unphosphorylated STAT3-unphosphorylated NF-κB pathway in loss of function STAT3 Hyper IgE syndrome.
Karim A, Garg R, Saikia B, Tiwari A, Sahu S, Malhotra M, Minz RW, Rawat A, Singh S, Suri D., Free PMC Article | 10/25/2024 |
| RNAi mediated silencing of STAT3/PD-L1 in tumor-associated immune cells induces robust anti-tumor effects in immunotherapy resistant tumors. | RNAi mediated silencing of STAT3/PD-L1 in tumor-associated immune cells induces robust anti-tumor effects in immunotherapy resistant tumors.
Ganesh S, Kim MJ, Lee J, Feng X, Ule K, Mahan A, Krishnan HS, Wang Z, Anzahaee MY, Singhal G, Korboukh I, Lockridge JA, Sanftner L, Rijnbrand R, Abrams M, Brown BD., | 10/22/2024 |
| Integrated Clinical Genotype-Phenotype Characteristics of STAT3-Mutated Myeloid Neoplasms. | Integrated Clinical Genotype-Phenotype Characteristics of STAT3-Mutated Myeloid Neoplasms.
Ye MT, Zuo Z, Calin S, Ye F, He H, Kamata W, Yang Y, You MJ. | 10/20/2024 |
| Unveiling the immunoregulatory role of interferon-induced transmembrane protein 2 through the JAK/STAT3/PDL1 pathway in gastric cancer. | Unveiling the immunoregulatory role of interferon-induced transmembrane protein 2 through the JAK/STAT3/PDL1 pathway in gastric cancer.
Liu Y, Liang J, Huang J, Li X, Huang J, Wang J. | 10/19/2024 |
| Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis. | Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis.
Mora P, Laisné M, Bourguignon C, Rouault P, Jaspard-Vinassa B, Maître M, Gadeau AP, Renault MA, Horng S, Couffinhal T, Chapouly C., Free PMC Article | 10/18/2024 |
| Long non-coding RNA TMEM147 antisense RNA 1/microRNA-124/signal transducer and activator of transcription 3 axis in estrogen receptor-positive breast cancer. | Long non-coding RNA TMEM147 antisense RNA 1/microRNA-124/signal transducer and activator of transcription 3 axis in estrogen receptor-positive breast cancer.
Liang W, Zhang X, Zhang J, Xia H, Wei X. | 10/18/2024 |
| Histones Methyltransferase NSD3 Inhibits Lung Adenocarcinoma Glycolysis Through Interacting with PPP1CB to Decrease STAT3 Signaling Pathway. | Histones Methyltransferase NSD3 Inhibits Lung Adenocarcinoma Glycolysis Through Interacting with PPP1CB to Decrease STAT3 Signaling Pathway.
Zhou Y, Peng X, Fang C, Peng X, Tang J, Wang Z, Long Y, Chen J, Peng Y, Zhang Z, Zhou Y, Tang J, Liao J, Xiao D, Tao Y, Shi Y, Liu S., Free PMC Article | 10/17/2024 |
| PDIA3 driven STAT3/PD-1 signaling promotes M2 TAM polarization and aggravates colorectal cancer progression. | PDIA3 driven STAT3/PD-1 signaling promotes M2 TAM polarization and aggravates colorectal cancer progression.
Fan J, Wang L, Zhang C, Wu X, Han L, Zhang X, Gao S, Xue J, Zhang Q., Free PMC Article | 10/10/2024 |
| De novo mutations promote inflammation in children with STAT3 gain-of-function syndrome by affecting IL-1beta expression. | De novo mutations promote inflammation in children with STAT3 gain-of-function syndrome by affecting IL-1β expression.
Chen JY, Li YF, Zhou Z, Jiang XM, Bi X, Yang MF, Zhao B. | 10/9/2024 |
| STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation. | STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation.
Luo L, Wang F, Xu X, Ma M, Kuang G, Zhang Y, Wang D, Li W, Zhang N, Zhao K., Free PMC Article | 10/8/2024 |
| STAT3-Mediated Ferroptosis is Involved in Sepsis-Associated Acute Respiratory Distress Syndrome. | STAT3-Mediated Ferroptosis is Involved in Sepsis-Associated Acute Respiratory Distress Syndrome.
Lin S, Yan J, Wang W, Luo L. | 10/3/2024 |
| KLF4 Induces Colorectal Cancer by Promoting EMT via STAT3 Activation. | KLF4 Induces Colorectal Cancer by Promoting EMT via STAT3 Activation.
Yuan L, Meng Y, Xiang J. | 10/3/2024 |
| SPRR1B+ keratinocytes prime oral mucosa for rapid wound healing via STAT3 activation. | SPRR1B+ keratinocytes prime oral mucosa for rapid wound healing via STAT3 activation.
Xuanyuan X, Zhang L, Zheng Y, Jiang R, Ma Y, Liu R, Hou P, Lei M, Xu H, Zeng H., Free PMC Article | 09/25/2024 |
| Mesenchymal stem cells-derived IL-6 promotes invasion and metastasis of oral squamous cell carcinoma via JAK-STAT3 signalling. | Mesenchymal stem cells-derived IL-6 promotes invasion and metastasis of oral squamous cell carcinoma via JAK-STAT3 signalling.
Liu C, Zhou J, Zhang S, Fu J, Li Y, Hao Y, Yuan J, Tang F, Ge W, He H, Chen Q. | 09/24/2024 |
| UBE2T mediates SORBS3 ubiquitination to enhance IL-6/STAT3 signaling and promote lung adenocarcinoma progression. | UBE2T mediates SORBS3 ubiquitination to enhance IL-6/STAT3 signaling and promote lung adenocarcinoma progression.
Pu J, Wang B, Zhang D, Wang K, Yang Z, Zhu P, Song Q. | 09/23/2024 |
| Zinc finger protein 263 promotes colorectal cancer cell progression by activating STAT3 and enhancing chemoradiotherapy resistance. | Zinc finger protein 263 promotes colorectal cancer cell progression by activating STAT3 and enhancing chemoradiotherapy resistance.
Du Y, Chen Y, Yan Z, Yang J, Da M., Free PMC Article | 09/19/2024 |
| HPV8-induced STAT3 activation led keratinocyte stem cell expansion in human actinic keratoses. | HPV8-induced STAT3 activation led keratinocyte stem cell expansion in human actinic keratoses.
Morgan HJ, Olivero C, Shorning BY, Gibbs A, Phillips AL, Ananthan L, Lim AXH, Martuscelli L, Borgogna C, De Andrea M, Hufbauer M, Goodwin R, Akgül B, Gariglio M, Patel GK., Free PMC Article | 09/17/2024 |
| Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway. | Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway.
Yuan H, Zhong M, Liu J, Tang S, Zhu H, Wei Q, Pu B, Li Y., Free PMC Article | 09/16/2024 |
| FGL1: a novel biomarker and target for non-small cell lung cancer, promoting tumor progression and metastasis through KDM4A/STAT3 transcription mechanism. | FGL1: a novel biomarker and target for non-small cell lung cancer, promoting tumor progression and metastasis through KDM4A/STAT3 transcription mechanism.
Liu TY, Yan JS, Li X, Xu L, Hao JL, Zhao SY, Hu QL, Na FJ, Li HM, Zhao Y, Zhao MF., Free PMC Article | 09/10/2024 |
| A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice. | A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice.
Toth KA, Schmitt EG, Kolicheski A, Greenberg ZJ, Levendosky E, Saucier N, Trammel K, Oikonomou V, Lionakis MS, Klechevsky E, Kim BS, Schuettpelz LG, Saligrama N, Cooper MA., Free PMC Article | 09/9/2024 |