| [TRIM21 Inhibits the Proliferation and Migration of Lung Adenocarcinoma Cells by Interacting with ZSWIM1]. | [TRIM21 Inhibits the Proliferation and Migration of Lung Adenocarcinoma Cells
by Interacting with ZSWIM1].
Chen L, Lian Q, Zhang G, Wu J, Zeng G, Gao X., Free PMC Article | 10/10/2024 |
| TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization. | TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization.
Reusch J, Franken LE, Then J, Ringler P, Butzer J, Juroschek T, Klein C, Schlothauer T, Larivière L., Free PMC Article | 07/10/2024 |
| TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway. | TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway.
Shu B, Zhou Y, Lei G, Peng Y, Ding C, Li Z, He C., Free PMC Article | 07/1/2024 |
| TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer. | TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer.
Wu Z, Zhang J, Jia Z, Yang Z, Liu S, Wang H, Zhao C, Zhao J, Tang Q, Xiong Y, Yang Y, Zhang Y, Zhou Z, Yue J, Xiao F, Sun Q, Gong A, Yao W, Li H, Song X, Ye Y, Zhu Y, Dong P, Ma F, Wu X, Gong W. | 06/8/2024 |
| The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis. | The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis.
Zhang R, Zhang D, Han F, Song X, Zhang Y, Zhang J, Zhu Q, Qin Y., Free PMC Article | 05/20/2024 |
| TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus. | TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus.
Wei Y, Gu Y, Zhou Z, Wu C, Liu Y, Sun H., Free PMC Article | 04/2/2024 |
| TRIM21 reduces H1N1-induced inflammation and apoptosis by regulating the TBK1-IRF3 signaling pathway in A549 cells. | TRIM21 reduces H1N1-induced inflammation and apoptosis by regulating the TBK1-IRF3 signaling pathway in A549 cells.
Yuan J, Pan J, Zhang X, Gao R. | 03/15/2024 |
| Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response. | Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
Li ZA, Bajpai AK, Wang R, Liu Y, Webby RJ, Wilk E, Gu W, Schughart K, Li K, Lu L., Free PMC Article | 03/6/2024 |
| FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination. | FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination.
Shi S, Zhang Q, Zhang K, Chen W, Xie H, Pan S, Xue Z, You B, Zhao J, You Y., Free PMC Article | 03/1/2024 |
| N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation. | N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation.
Xie R, Liu L, Lu X, He C, Yao H, Li G., Free PMC Article | 01/9/2024 |
| Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination. | Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination.
Wang L, Li H, Huang A, Zhao Y, Xiao C, Dong J, Liu X, Shao N. | 12/21/2023 |
| Ro52/TRIM21 - From host defense to autoimmunity. | Ro52/TRIM21 - From host defense to autoimmunity.
Holwek E, Opinc-Rosiak A, Sarnik J, Makowska J. | 12/6/2023 |
| Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression. | Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression.
Liu F, Liao Z, Qin L, Zhang Z, Zhang Q, Han S, Zeng W, Zhang H, Liu Y, Song J, Chen W, Zhu H, Liang H, Chen X, Zhang B, Zhang Z., Free PMC Article | 11/15/2023 |
| Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/beta-catenin signaling. | Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling.
Liu RX, Gu RH, Li ZP, Hao ZQ, Hu QX, Li ZY, Wang XG, Tang W, Wang XH, Zeng YK, Li ZW, Dong Q, Zhu XF, Chen D, Zhao KW, Zhang RH, Zha ZG, Zhang HT., Free PMC Article | 11/15/2023 |
| Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators. | Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators.
Nikolaou KC, Godbersen S, Manoharan M, Wieland S, Heim MH, Stoffel M., Free PMC Article | 11/14/2023 |
| TRIM21-Promoted FSP1 Plasma Membrane Translocation Confers Ferroptosis Resistance in Human Cancers. | TRIM21-Promoted FSP1 Plasma Membrane Translocation Confers Ferroptosis Resistance in Human Cancers.
Gong J, Liu Y, Wang W, He R, Xia Q, Chen L, Zhao C, Gao Y, Shi Y, Bai Y, Liao Y, Zhang Q, Zhu F, Wang M, Li X, Qin R., Free PMC Article | 11/10/2023 |
| TRIM21 enhances bortezomib sensitivity in multiple myeloma by halting prosurvival autophagy. | TRIM21 enhances bortezomib sensitivity in multiple myeloma by halting prosurvival autophagy.
Chen J, Cao W, Huang X, Chen Q, Ye S, Qu J, Liu Y, Guo X, Yao S, Zhang E, He J, Li A, Yang L, Cai Z., Free PMC Article | 11/7/2023 |
| STAT1 suppresses the transcriptional activity of TRIM21 in gastric cancer. | STAT1 suppresses the transcriptional activity of TRIM21 in gastric cancer.
Huo C, Gu Y, Wang D, Zhang X, Tang F, Zhao B, Liu T, He W, Li Y. | 11/6/2023 |
| BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1. | BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1.
Xu C, Yang K, Xuan Z, Li J, Liu Y, Zhao Y, Zheng Z, Bai Y, Shi Z, Shao C, Zhang L, Sun H., Free PMC Article | 10/20/2023 |
| USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/beta-catenin signaling pathway. | USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway.
Liu Y, Ma J, Lu S, He P, Dong W., Free PMC Article | 09/23/2023 |
| MANF inhibits Sjogren's syndrome salivary gland epithelial cell apoptosis and antigen expression of Ro52/SSA through endoplasmic reticulum stress/autophagy pathway. | MANF inhibits Sjögren's syndrome salivary gland epithelial cell apoptosis and antigen expression of Ro52/SSA through endoplasmic reticulum stress/autophagy pathway.
Cheng D, Zhou T, Liu H, Li L, Xuan Y, Huang L, Liu Y, Zhang X, Wei W, Wu H. | 08/28/2023 |
| TRIM21 promotes tumor progression and cancer stemness in cervical squamous cell carcinoma. | TRIM21 promotes tumor progression and cancer stemness in cervical squamous cell carcinoma.
Yang Y, Zuo S, Li W, Di M, Liu J, Chai J, Wang J, Yuan Y, Li M, Jia Q. | 08/17/2023 |
| Regulation of hPCL3 isoforms' ubiquitination by TRIM21 in non-small cell lung cancer progression. | Regulation of hPCL3 isoforms' ubiquitination by TRIM21 in non-small cell lung cancer progression.
Xu Y, Liu W, Jiang X, Li J, Liu Q, Su F, Ruan S, Zhang Z, Tao F., Free PMC Article | 08/14/2023 |
| TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2. | TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2.
Liu YX, Wan S, Yang XQ, Wang Y, Gan WJ, Ye WL, He XS, Chen JJ, Yang Y, Yang XM, Guo X, Gao XJ, Lu YT, Deng ZY, Hu G, Wu H. | 08/3/2023 |
| TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway. | TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway.
Benton D, Chernoff J. | 07/25/2023 |