| Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism. | Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism.
Shi YH, Liu ZD, Ma MJ, Zhao GY, Zhu YQ, Wang JQ, Yu YY, Huang XT, Ye JY, Li FX, Wang XY, Xu QC, Yin XY., Free PMC Article | 11/5/2024 |
| PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy. | PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy.
Chen X, Ruiz-Velasco A, Zou Z, Hille SS, Ross C, Fonseka O, Gare SR, Alatawi NHO, Raja R, Zhang J, Kaur N, Zhao X, Morrell-Davies H, Miller JM, Abouleisa RRE, Ou Q, Frank D, Rutter MK, Pinali C, Wang T, Mohamed TMA, Müller OJ, Liu W., | 10/30/2024 |
| A gain-of-function variant in SREBF1 causes generalized skin hyperpigmentation with congenital cataracts. | A gain-of-function variant in SREBF1 causes generalized skin hyperpigmentation with congenital cataracts.
Wang H, Wu Y, Bassetti JA, Wang Z, Oza VS, Rangu SA, McGivern B, Peng S, Liang L, Huang S, Gong Z, Xu Z, Lin Z. | 10/28/2024 |
| FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1. | FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1.
Dong C, Zhang Y, Zeng J, Chong S, Liu Y, Bian Z, Fan S, Chen X., Free PMC Article | 10/21/2024 |
| STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/beta-catenin signaling pathway. | STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/β-catenin signaling pathway.
Jin J, Wang Y, Hu Y. | 10/15/2024 |
| CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation. | CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation.
Jin Q, Qi D, Zhang M, Qu H, Dong Y, Sun M, Quan C., Free PMC Article | 10/2/2024 |
| CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1. | CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1.
Kong Y, Yang G, Feng X, Ji Z, Wang X, Shao Y, Meng J, Yao G, Ren C, Yang G., Free PMC Article | 09/19/2024 |
| SREBP-1-mediated lipogenesis confers resistance to ferroptosis and improves endothelial injury. | SREBP-1-mediated lipogenesis confers resistance to ferroptosis and improves endothelial injury.
Wang X, Chen Y, Meng H, Ruan J, Meng F. | 08/1/2024 |
| Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer. | Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.
Huang F, Zhao N, Cai P, Hou M, Yang S, Zheng B, Ma Q, Jiang J, Gai X, Mao Y, Wang L, Hu Z, Zha X, Liu F, Zhang H. | 05/13/2024 |
| FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway. | FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway.
Xu Y, Hu H, An J, Zong L. | 03/13/2024 |
| Association of adipocyte size and SREBP-1c in visceral and subcutaneous adipose tissue in non-obese type 2 diabetes mellitus. | Association of adipocyte size and SREBP-1c in visceral and subcutaneous adipose tissue in non-obese type 2 diabetes mellitus.
Adhikary P, Banerjee S, Dey BK, Gargari P, Chatterjee S, Chakraborty D, Chowdhury S. | 03/4/2024 |
| The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis. | The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis.
Chandrasekaran P, Weiskirchen R., Free PMC Article | 02/28/2024 |
| Expression and correlation analysis of silent information regulator 1 (SIRT1), sterol regulatory element-binding protein-1 (SREBP1), and pyroptosis factor in gestational diabetes mellitus. | Expression and correlation analysis of silent information regulator 1 (SIRT1), sterol regulatory element-binding protein-1 (SREBP1), and pyroptosis factor in gestational diabetes mellitus.
Han N, Chang XY, Yuan ZL, Wang YZ. | 02/14/2024 |
| EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression. | EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression.
Wang Z, Chao Z, Wang Q, Zou F, Song T, Xu L, Ning J, Cheng F., Free PMC Article | 01/30/2024 |
| Exogenous H2 S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration. | Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W., Free PMC Article | 01/6/2024 |
| Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma. | Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma.
Jeong DW, Park JW, Kim KS, Kim J, Huh J, Seo J, Kim YL, Cho JY, Lee KW, Fukuda J, Chun YS., Free PMC Article | 11/18/2023 |
| Recurrent Vascularizing Keratitis in Infants With Hereditary Mucoepithelial Dysplasia Related to SREBF1 Mutation. | Recurrent Vascularizing Keratitis in Infants With Hereditary Mucoepithelial Dysplasia Related to SREBF1 Mutation.
Kim S, Jeong H, Ko JM, Kwon O, Oh JY. | 11/13/2023 |
| FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. | FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1.
Cho S, Chun Y, He L, Ramirez CB, Ganesh KS, Jeong K, Song J, Cheong JG, Li Z, Choi J, Kim J, Koundouros N, Ding F, Dephoure N, Jang C, Blenis J, Lee G., Free PMC Article | 08/25/2023 |
| MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis. | MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.
Zhang S, Zhong J, Guo D, Zhang S, Huang G, Chen Y, Xu C, Chen W, Zhang Q, Zhao C, Liu S, Luo Z, Lin C. | 08/22/2023 |
| Kruppel-like factor 4 (KLF4) facilitates lipid production in immortalized human sebocytes via regulating the expression of SREBP1. | Krüppel-like factor 4 (KLF4) facilitates lipid production in immortalized human sebocytes via regulating the expression of SREBP1.
Li X, Zeng X, Kim D, Jiang J, Wei F, Zhang J, Chai B, Fu L, Lee Y, Kim C, Chen H. | 06/7/2023 |
| Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes. | Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes.
Kamoshita K, Ishii KA, Tahira Y, Kikuchi A, Abuduwaili H, Tajima-Shirasaki N, Li Q, Takayama H, Matsumoto K, Takamura T. | 03/23/2023 |
| TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability. | TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.
Chen X, Yong H, Chen M, Deng C, Wang P, Chu S, Li M, Hou P, Zheng J, Li Z, Bai J., Free PMC Article | 02/4/2023 |
| Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis. | Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis.
Zhu Y, Yang Y, Bu H, Huang H, Chen H, Ran J, Qin L, Ni Y, Yao M, Song T, Li M, Yang Y, Guo T, Chao N, Liu Z, Li W, Zhang L., Free PMC Article | 11/12/2022 |
| [Research on the mechanism of hypoxia promoting the migration of lung adenocarcinoma A549 cells]. | [Research on the mechanism of hypoxia promoting the migration of lung adenocarcinoma A549 cells].
Jin JH, Zhao BS, Liu YZ. | 06/11/2022 |
| Leptin Silencing Attenuates Lipid Accumulation through Sterol Regulatory Element-Binding Protein 1 Inhibition in Nasopharyngeal Carcinoma. | Leptin Silencing Attenuates Lipid Accumulation through Sterol Regulatory Element-Binding Protein 1 Inhibition in Nasopharyngeal Carcinoma.
Luo SD, Tsai HT, Chiu TJ, Li SH, Hsu YL, Su LJ, Tsai MH, Lee CY, Hsiao CC, Chen CH., Free PMC Article | 06/11/2022 |