| Circ_0009910 Serves as miR-361-3p Sponge to Promote the Proliferation, Metastasis, and Glycolysis of Gastric Cancer via Regulating SNRPA. | Circ_0009910 Serves as miR-361-3p Sponge to Promote the Proliferation, Metastasis, and Glycolysis of Gastric Cancer via Regulating SNRPA.
Liu J, Li J, Su Y, Ma Z, Yu S, He Y. | 09/24/2022 |
| The Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA) binds to the G-quadruplex of the BAG-1 5'UTR. | The Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA) binds to the G-quadruplex of the BAG-1 5'UTR.
Bolduc F, Turcotte MA, Perreault JP. | 01/9/2021 |
| Screen using siRNA revealed depletion of U1 snRNP components SNRPA, SNRNP70 or SNRPD2 caused significant cytoplasmic localization of MEG3 reporter transcripts. | Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus.
Azam S, Hou S, Zhu B, Wang W, Hao T, Bu X, Khan M, Lei H., Free PMC Article | 03/21/2020 |
| the previously unreported concurrence of intellectual disability, short stature, poor speech, and minor craniofacial and hand anomalies in 2 female siblings with 3 homozygous missense variants in SNRPA, is reported. | Exome sequencing reveals three homozygous missense variants in SNRPA in two sisters with syndromic intellectual disability.
Rangel-Sosa MM, Figuera-Villanueva LE, González-Ramos IA, Pérez-Páramo YX, Martínez-Jacobo LA, Arnaud-López L, Nastasi-Catanese JA, Rivas-Estilla AM, Galán-Huerta KA, Rojas-Martínez A, Ortiz-López R, Córdova-Fletes C. | 12/7/2019 |
| SNRPA may contribute to GC progression via NGF and could be a prognostic biomarker for GC. | SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression.
Dou N, Yang D, Yu S, Wu B, Gao Y, Li Y., Free PMC Article | 10/6/2018 |
| p65 activation triggered by TCR signaling could promote SNRPA transcription and 3' UTR shortening of STAT5B. Thus we propose that the alternative polyadenylation switching of STAT5B induced by TCR activation is mediated by SNRPA. | Small Nuclear Ribonucleoprotein Polypeptide A-Mediated Alternative Polyadenylation of STAT5B during Th1 Cell Differentiation.
Qiu F, Fu Y, Lu C, Feng Y, Wang Q, Huo Z, Jia X, Chen C, Chen S, Xu A. | 10/28/2017 |
| a new mechanism for regulating SMN levels and provides new insight into the roles of U1A in 3' processing of mRNAs. | U1A regulates 3' processing of the survival motor neuron mRNA.
Workman E, Veith A, Battle DJ., Free PMC Article | 04/12/2014 |
| An analysis of the kinetic data suggests three phases of U1A-SL2 RNA complex dissociation with time scales of approximately 100 mus, approximately 50 ms, and approximately 2 s. We propose that the first step of dissociation is a fast rearrangement of the complex to form a loosely bound complex. | Multistep kinetics of the U1A-SL2 RNA complex dissociation.
Anunciado D, Dhar A, Gruebele M, Baranger AM. | 11/24/2012 |
| structural analysis of U1A protein-stem loop 2 RNA recognition | U1A protein-stem loop 2 RNA recognition: prediction of structural differences from protein mutations.
Kormos BL, Pieniazek SN, Beveridge DL, Baranger AM., Free PMC Article | 09/10/2011 |
| study shows that the yellow fever virus (YFV) NS5 protein is able to interact with U1A, a protein involved in splicing and polyadenylation; a region between amino acids 368 and 448 was identified as the site of interaction of the NS5 protein with U1A | The small nuclear ribonucleoprotein U1A interacts with NS5 from yellow fever virus.
Bronzoni RV, Madrid MC, Duarte DV, Pellegrini VO, Pacca CC, Carmo AC, Zanelli CF, Valentini SR, Santacruz-Pérez C, Barbosa JA, Lutz CS, Rahal P, Nogueira ML. | 08/6/2011 |
| Functional U1A site in a cellular gene and of a single gene containing two dissimilar elements that inhibit nuclear polyadenylation. | A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation.
Guan F, Caratozzolo RM, Goraczniak R, Ho ES, Gunderson SI., Free PMC Article | 01/21/2010 |
| Identification of PSF, p54(nrb), PTB, and U1A as proteins specifically bound to the COX-2 polyadenylation signal upstream sequence elements . | Specific trans-acting proteins interact with auxiliary RNA polyadenylation elements in the COX-2 3'-UTR.
Hall-Pogar T, Liang S, Hague LK, Lutz CS., Free PMC Article | 01/21/2010 |
| 13)C NMR relaxation studies of base and ribose dynamics for the RNA internal loop target of human U1A protein located within the 3'-untranslated region (3'-UTR) of the mRNA coding for U1A itself | 13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein.
Shajani Z, Varani G. | 01/21/2010 |