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    SLC6A3 solute carrier family 6 member 3 [ Homo sapiens (human) ]

    Gene ID: 6531, updated on 4-Jan-2025

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Structure of the human dopamine transporter in complex with cocaine.

    Structure of the human dopamine transporter in complex with cocaine.
    Nielsen JC, Salomon K, Kalenderoglou IE, Bargmeyer S, Pape T, Shahsavar A, Loland CJ.

    08/16/2024
    Gene Interaction of Dopaminergic Synaptic Pathway Genes in Attention-Deficit Hyperactivity Disorder: a Case-Control Study in Chinese Children.

    Gene Interaction of Dopaminergic Synaptic Pathway Genes in Attention-Deficit Hyperactivity Disorder: a Case-Control Study in Chinese Children.
    Zhong L, He H, Zhang J, Gao X, Yin F, Zuo P, Song R., Free PMC Article

    01/17/2024
    Association between longitudinal changes in striatal dopamine transporter uptake and clinical features of dementia with Lewy bodies.

    Association between longitudinal changes in striatal dopamine transporter uptake and clinical features of dementia with Lewy bodies.
    Yamamoto R, Takenoshita N, Inagawa Y, Kato H, Kaneshiro K, Kamiya T, Inagawa S, Saisho A, Tsugawa A, Mastumoto Y, Yoshimura M, Saito K, Shimizu S, Sato T.

    11/8/2023
    Effects of STN-DBS surgery on cerebral glucose metabolism and distribution of DAT in Parkinson's disease.

    Effects of STN-DBS surgery on cerebral glucose metabolism and distribution of DAT in Parkinson's disease.
    Luo G, Shi X, Jiang L, Wu L, Yi C, Xian W, Liu Y, Wen F, Qian H, Chen J, Fu X, Liu J, Zhang X, Chen L., Free PMC Article

    09/6/2023
    LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma.

    LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma.
    Correa-Arzate L, Portilla-Robertson J, Ramírez-Jarquín JO, Jacinto-Alemán LF, Mejía-Velázquez CP, Villanueva-Sánchez FG, Rodríguez-Vázquez M., Free PMC Article

    08/30/2023
    Structure-Based Discovery of a Novel Allosteric Inhibitor against Human Dopamine Transporter.

    Structure-Based Discovery of a Novel Allosteric Inhibitor against Human Dopamine Transporter.
    Deng S, Zhang H, Gou R, Luo D, Liu Z, Zhu F, Xue W.

    07/27/2023
    Striatal dopamine transporter and receptor availability correlate with relative cerebral blood flow measured with [[11]C]PE2I, [[18]F]FE-PE2I and [[11]C]raclopride PET in healthy individuals.

    Striatal dopamine transporter and receptor availability correlate with relative cerebral blood flow measured with [(11)C]PE2I, [(18)F]FE-PE2I and [(11)C]raclopride PET in healthy individuals.
    Jonasson M, Frick A, Fazio P, Hjorth O, Danfors T, Axelsson J, Appel L, Furmark T, Varrone A, Lubberink M., Free PMC Article

    06/29/2023
    A novel hypervariable variable number tandem repeat in the dopamine transporter gene (SLC6A3).

    A novel hypervariable variable number tandem repeat in the dopamine transporter gene (SLC6A3).
    Apsley AT, Domico ER, Verbiest MA, Brogan CA, Buck ER, Burich AJ, Cardone KM, Stone WJ, Anisimova M, Vandenbergh DJ., Free PMC Article

    02/13/2023
    Driving risks of young drivers with symptoms of attention deficit hyperactivity disorder: association with the dopamine transporter gene VNTR polymorphism.

    Driving risks of young drivers with symptoms of attention deficit hyperactivity disorder: association with the dopamine transporter gene VNTR polymorphism.
    Tokko T, Miškinyte G, Eensoo D, Harro J.

    11/12/2022
    Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother-child interaction.

    Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother-child interaction.
    Pascale E, Cimino S, Cerniglia L, Bevilacqua A., Free PMC Article

    10/22/2022
    Interaction between manganese and SLC6A3 genetic polymorphisms in relation to dyslexia.

    Interaction between manganese and SLC6A3 genetic polymorphisms in relation to dyslexia.
    Zhu K, Liu Q, Xie X, Jiang Q, Feng Y, Xiao P, Wu X, Zhu B, Song R.

    10/1/2022
    Methylation in the Promoter Region of the Dopamine Transporter DAT1 Gene in People Addicted to Nicotine.

    Methylation in the Promoter Region of the Dopamine Transporter DAT1 Gene in People Addicted to Nicotine.
    Chmielowiec J, Chmielowiec K, Strońska-Pluta A, Suchanecka A, Humińska-Lisowska K, Lachowicz M, Niewczas M, Białecka M, Śmiarowska M, Grzywacz A., Free PMC Article

    08/6/2022
    Association between dopamine transporter gene (DAT1/SLC6A3) variants and infertility in the Turkish females.

    Association between dopamine transporter gene (DAT1/SLC6A3) variants and infertility in the Turkish females.
    Avsar O, Derinoz N, Yilmaz F, Yilmaz M, Gorkem U.

    07/9/2022
    Functional SLC6A3 polymorphisms differentially affect autism spectrum disorder severity: a study on Indian subjects.

    Functional SLC6A3 polymorphisms differentially affect autism spectrum disorder severity: a study on Indian subjects.
    Saha S, Chatterjee M, Shom S, Sinha S, Mukhopadhyay K.

    04/23/2022
    Functional characterization of the biogenic amine transporters on human macrophages.

    Functional characterization of the biogenic amine transporters on human macrophages.
    Mackie PM, Gopinath A, Montas DM, Nielsen A, Smith A, Nolan RA, Runner K, Matt SM, McNamee J, Riklan JE, Adachi K, Doty A, Ramirez-Zamora A, Yan L, Gaskill PJ, Streit WJ, Okun MS, Khoshbouei H., Free PMC Article

    04/2/2022
    Analysis of Relationships between DAT1 Polymorphism Variants, Personality Dimensions, and Anxiety in New Psychoactive Substance (Designer Drug) (NPS) Users.

    Analysis of Relationships between DAT1 Polymorphism Variants, Personality Dimensions, and Anxiety in New Psychoactive Substance (Designer Drug) (NPS) Users.
    Chmielowiec J, Chmielowiec K, Masiak J, Pawłowski T, Larysz D, Grzywacz A., Free PMC Article

    02/19/2022
    Influence of DAT1 Promotor Methylation on Sports Performance.

    Influence of DAT1 Promotor Methylation on Sports Performance.
    Grzywacz A, Chmielowiec K, Boroń A, Michałowska-Sawczyn M, Chmielowiec J, Trybek G, Mroczek B, Leźnicka K, Cieszczyk P, Masiak J., Free PMC Article

    02/19/2022
    Mutations of Human DopamineTransporter at Tyrosine88, Aspartic Acid206, and Histidine547 Influence Basal and HIV-1 Tat-inhibited Dopamine Transport.

    Mutations of Human DopamineTransporter at Tyrosine88, Aspartic Acid206, and Histidine547 Influence Basal and HIV-1 Tat-inhibited Dopamine Transport.
    Quizon PM, Yuan Y, Zhu Y, Zhou Y, Strauss MJ, Sun WL, Zhan CG, Zhu J., Free PMC Article

    02/5/2022
    Epigenetic regulation of DAT gene promoter modulates the risk of externalizing and internalizing behaviors on a normative population: An explorative study.

    Epigenetic regulation of DAT gene promoter modulates the risk of externalizing and internalizing behaviors on a normative population: An explorative study.
    Carpentieri V, Cerniglia L, Cimino S, Pucci M, Pascale E, D'Addario C, Adriani W.

    01/29/2022
    SLC6A3 as a potential circulating biomarker for gastric cancer detection and progression monitoring.

    SLC6A3 as a potential circulating biomarker for gastric cancer detection and progression monitoring.
    Liu S, Cui M, Zang J, Wang J, Shi X, Qian F, Xu S, Jing R.

    11/27/2021
    Cross-correlations between motifs in the 5'-UTR of DAT1 gene: Findings from Parkinson's disease.

    Cross-correlations between motifs in the 5'-UTR of DAT1 gene: Findings from Parkinson's disease.
    Tafani X, Pascale E, Fattapposta F, Pucci M, D'Addario C, Adriani W.

    10/16/2021
    SLC6A3 (DAT1) as a Novel Candidate Biomarker Gene for Suicidal Behavior.

    SLC6A3 (DAT1) as a Novel Candidate Biomarker Gene for Suicidal Behavior.
    Rafikova E, Shadrina M, Slominsky P, Guekht A, Ryskov A, Shibalev D, Vasilyev V., Free PMC Article

    09/25/2021
    Dopamine transporter (DAT1) gene in combat veterans with PTSD: A case-control study.

    Dopamine transporter (DAT1) gene in combat veterans with PTSD: A case-control study.
    Zuschlag ZD, Compean E, Nietert P, Lauzon S, Hamner M, Wang Z., Free PMC Article

    09/25/2021
    Optogenetically-induced multimerization of the dopamine transporter increases uptake and trafficking to the plasma membrane.

    Optogenetically-induced multimerization of the dopamine transporter increases uptake and trafficking to the plasma membrane.
    Ingram SM, Rana T, Manson AM, Yayah FM, Jackson EGB, Anderson C, Davids BO, Goodwin JS., Free PMC Article

    09/4/2021
    Smoking Genes: A Case-Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort.

    Smoking Genes: A Case-Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort.
    Ruzilawati AB, Islam MA, Muhamed SKS, Ahmad I., Free PMC Article

    09/4/2021
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