Clinical potential of SKP2 as diagnostic marker and therapeutic target in small cell lung cancer.
Matsumoto N, Tajima K, Takahashi F, Mitsuishi Y, Wirawan A, Hidayat M, Winardi W, Wibowo A, Hayakawa D, Izumi K, Kanamori K, Miyashita Y, Handa T, Asao T, Ko R, Shukuya T, Shimada N, Takamochi K, Hayashi T, Suzuki K, Takahashi K.

Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27(KIP1) Regulation.
Cigliano A, Simile MM, Vidili G, Pes GM, Dore MP, Urigo F, Cossu E, Che L, Feo C, Steinmann SM, Ribback S, Pascale RM, Evert M, Chen X, Calvisi DF., Free PMC Article

Promoter methylation and enhanced SKP2 are associated with the downregulation of CDKN1C in cervical squamous cell carcinoma.
Roychowdhury A, Pal D, Basu M, Samadder S, Mondal R, Roy A, Roychoudhury S, Panda CK.

O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation.
Feng Z, Yin J, Zhang Z, Chen Z, Huang L, Tang N, Wang K.

Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2.
Zhuang M, Li F, Liang H, Su Y, Cheng L, Lin B, Zhou J, Deng R, Chen L, Lyu P, Lu Z., Free PMC Article

Targeted inhibition of SCF(SKP2) confers anti-tumor activities resulting in a survival benefit in osteosarcoma.
Wang J, Ferrena A, Zhang R, Singh S, Viscarret V, Al-Harden W, Aldahamsheh O, Borjihan H, Singla A, Yaguare S, Tingling J, Zi X, Lo Y, Gorlick R, Schwartz EL, Zhao H, Yang R, Geller DS, Zheng D, Hoang BH., Free PMC Article

Skp2: A critical molecule for ubiquitination and its role in cancer.
Feng T, Wang P, Zhang X.

SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis.
Ferrena A, Wang J, Zhang R, Karadal-Ferrena B, Al-Hardan W, Singh S, Borjihan H, Schwartz EL, Zhao H, Oktay MH, Yang R, Geller DS, Hoang BH, Zheng D., Free PMC Article

MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57(Kip2) targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R., Free PMC Article

A critical role of the endothelial S-phase kinase-associated protein 2/phosphatase and tensin homologue axis in angiogenesis and psoriasis.
Xie X, Cui Q, Jiang T, Zhao Z, Liu Z, Liu J, Yao Q, Wang Y, Dang E, Wang G, Xiao L, Wang N.

Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury.
Wu Y, Li J, Yang X, Hou B, Qiao H.

LncRNA POU6F2-AS2 contributes to malignant phenotypes and paclitaxel resistance by promoting SKP2 expression in stomach adenocarcinoma.
Jin Y, Cao J, Cheng H, Hu X.

Skp2-mediated MLKL degradation confers cisplatin-resistant in non-small cell lung cancer cells.
Zhou H, Zhou L, Guan Q, Hou X, Wang C, Liu L, Wang J, Yu X, Li W, Liu H., Free PMC Article

SKP2 Contributes to AKT Activation by Ubiquitination Degradation of PHLPP1, Impedes Autophagy, and Facilitates the Survival of Thyroid Carcinoma.
Shao Y, Ren W, Dai H, Yang F, Li X, Zhang S, Liu J, Yao X, Zhao Q, Sun X, Zheng Z, Xu C., Free PMC Article

Reduced SKP2 Expression Adversely Impacts Genome Stability and Promotes Cellular Transformation in Colonic Epithelial Cells.
Neudorf NM, Thompson LL, Lichtensztejn Z, Razi T, McManus KJ., Free PMC Article

Expression and correlation analysis of Skp2 and CBX7 in cervical cancer.
Maimaitirexiati G, Tian P, Maimaiti H, Ding L, Ma C, Li Y, Wang J, Yan Q, Li R.

The SKP2-p27 axis defines susceptibility to cell death upon CHK1 inhibition.
Lohmüller M, Roeck BF, Szabo TG, Schapfl MA, Pegka F, Herzog S, Villunger A, Schuler F., Free PMC Article

miR-590-5p Targets Skp2 to Inhibit the Growth and Invasion of Malignant Melanoma Cells.
Tong Y, Jin L., Free PMC Article

The Impact of SKP2 Gene Expression in Chronic Myeloid Leukemia.
Hodeib H, Abd El Hai D, Tawfik MA, Allam AA, Selim AF, Sarhan ME, Selim A, Sabry NM, Mansour W, Youssef A., Free PMC Article

Skp2 stabilizes Mcl-1 and confers radioresistance in colorectal cancer.
Yu X, Zhou L, Liu W, Liu L, Gao F, Li W, Liu H., Free PMC Article

RIP1-dependent Apoptosis and Differentiation Regulated by Skp2 and Akt/GSK3β in Acute Myeloid Leukemia.
Dan W, Zhong L, Zhang Z, Wan P, Lu Y, Wang X, Liu Z, Chu X, Liu B., Free PMC Article

Regulation of SKP2 protein stability by heat shock protein 90 chaperone machinery.
Cai L, Li L, Chen X, Jia L., Free PMC Article

Bipartite binding of the N terminus of Skp2 to cyclin A.
Kelso S, Orlicky S, Beenstock J, Ceccarelli DF, Kurinov I, Gish G, Sicheri F., Free PMC Article

SKP2 regulates ZEB1 expression and stimulates eutopic endometrial stromal cell invasion and proliferation of adenomyosis.
Guo Y, Wang J, Jia C, Liao Y.

A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer.
Fong LWR, Lee J, Lin HK, Ueno NT, Zhang S., Free PMC Article