| SRSF7 downregulation induces cellular senescence through generation of MDM2 variants. | SRSF7 downregulation induces cellular senescence through generation of MDM2 variants.
Hong J, Min S, Yoon G, Lim SB., Free PMC Article | 01/30/2024 |
| Specific Regulation of m[6]A by SRSF7 Promotes the Progression of Glioblastoma. | Specific Regulation of m(6)A by SRSF7 Promotes the Progression of Glioblastoma.
Cun Y, An S, Zheng H, Lan J, Chen W, Luo W, Yao C, Li X, Huang X, Sun X, Wu Z, Hu Y, Li Z, Zhang S, Wu G, Yang M, Tang M, Yu R, Liao X, Gao G, Zhao W, Wang J, Li J., Free PMC Article | 01/12/2024 |
| The splicing factor 9G8 regulates the expression of NADPH-producing enzyme genes in Drosophila. | The splicing factor 9G8 regulates the expression of NADPH-producing enzyme genes in Drosophila.
Weidman T, Nagengast AA, DiAngelo JR. | 07/30/2022 |
| Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway. | Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway.
Khan M, Hou S, Azam S, Lei H., Free PMC Article | 07/17/2021 |
| Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer. | Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.
Song J, Su ZZ, Shen QM. | 03/20/2021 |
| role of SRSF7 in cell proliferation through regulating p21 levels. | Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells.
Saijo S, Kuwano Y, Masuda K, Nishikawa T, Rokutan K, Nishida K. | 06/24/2017 |
| SRSF7 expression in cancer cells is regulated by microRNAs: short, non-coding RNAs that bind to 3'UTR of target genes and downregulate their expression. SRSF7 regulate proliferation of renal cancer cells.SRSF7 regulates expression of osteopontin. | microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells.
Boguslawska J, Sokol E, Rybicka B, Czubaty A, Rodzik K, Piekielko-Witkowska A. | 01/28/2017 |
| Genome-wide identification of CD95 antigen alternative splicing regulators, such as SRSF7, reveals links with iron homeostasis. | Genome-wide identification of Fas/CD95 alternative splicing regulators reveals links with iron homeostasis.
Tejedor JR, Papasaikas P, Valcárcel J. | 04/11/2015 |
| Coexpression of Dyrk1A and splicing factor 9G8 leads to their translocation from the nucleus to the cytoplasm and suppresses their ability to regulate tau exon 10 splicing. | Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A.
Ding S, Shi J, Qian W, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F., Free PMC Article | 06/1/2013 |
| Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10 | Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10.
Gu J, Shi J, Wu S, Jin N, Qian W, Zhou J, Iqbal IG, Iqbal K, Gong CX, Liu F. | 10/13/2012 |
| Upregulation of total tau expression (SFRS7-independent) and tau exon 10 splicing (SFRS7-dependent), as shown in this study to be both affected by STOX1A, is known to have implications in neurodegeneration. | SFRS7-mediated splicing of tau exon 10 is directly regulated by STOX1A in glial cells.
van Abel D, Hölzel DR, Jain S, Lun FM, Zheng YW, Chen EZ, Sun H, Chiu RW, Lo YM, van Dijk M, Oudejans CB., Free PMC Article | 11/12/2011 |
| The authors report that siRNA knockdown of SRp20 or 9G8 resulted in about a 10 fold decrease in herpes simplex virus 1 yields and in nuclear accumulation of polyA+ RNA. | SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs.
Escudero-Paunetto L, Li L, Hernandez FP, Sandri-Goldin RM., Free PMC Article | 05/31/2010 |
| eIF3f mediates restriction of HIV-1 expression through a set of factors that includes eIF3f, the SR protein 9G8, and the cyclin-dependent kinase 11 (CDK11). | HIV-1 mRNA 3' end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8.
Valente ST, Gilmartin GM, Venkatarama K, Arriagada G, Goff SP., Free PMC Article | 01/21/2010 |
| Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW. | 01/28/2009 |
| 9G8 was shown to enhance expression of unspliced RNA containing either the Mason-Pfizer monkey virus constitutive transport element | The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element.
Swartz JE, Bor YC, Misawa Y, Rekosh D, Hammarskjold ML. | 01/21/2010 |
| SR proteins 9G8 and ASF/SF2 exhibit higher affinity for TAP/NXF1 when hypophosphorylated | A molecular link between SR protein dephosphorylation and mRNA export.
Huang Y, Yario TA, Steitz JA., Free PMC Article | 01/21/2010 |
| These results indicate that 9G8 plays a key role in regulation of exon 10 splicing and imply a pathogenic role in neurodegenerative diseases. | SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations.
Gao L, Wang J, Wang Y, Andreadis A., Free PMC Article | 01/21/2010 |
| SR proteins 9G8, SC35, ASF/SF2, and SRp40 have effects on the utilization of the A1 to A5 splicing sites of HIV-1 RNA | Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA.
Ropers D, Ayadi L, Gattoni R, Jacquenet S, Damier L, Branlant C, Stévenin J. | 01/21/2010 |
| SR proteins ASF/SF2, SC35 and 9G8 can down-regulate the late steps of HIV-1 replication via negative impact on RNA splicing and virion production. | Dual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production.
Jacquenet S, Decimo D, Muriaux D, Darlix JL., Free PMC Article | 01/21/2010 |