Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fasting. | Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fasting. Tripathi M, Gauthier K, Sandireddy R, Zhou J, Guptta P, Sakthivel S, Teo WW, Naing YT, Arul K, Tikno K, Park SH, Wu Y, Wang L, Bay BH, Sun L, Giguere V, Chow PKH, Ghosh S, McDonnell DP, Yen PM, Singh BK., Free PMC Article | 09/12/2024 |
RPLP1 restricts HIV-1 transcription by disrupting C/EBPbeta binding to the LTR. | RPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR. Yang W, Wang H, Li Z, Zhang L, Liu J, Kirchhoff F, Huan C, Zhang W., Free PMC Article | 07/19/2024 |
RPLP1 Is Up-Regulated in Human Adenomyosis and Endometrial Adenocarcinoma Epithelial Cells and Is Essential for Cell Survival and Migration In Vitro. | RPLP1 Is Up-Regulated in Human Adenomyosis and Endometrial Adenocarcinoma Epithelial Cells and Is Essential for Cell Survival and Migration In Vitro. Peterson R, Minchella P, Cui W, Graham A, Nothnick WB., Free PMC Article | 02/16/2023 |
Phosphorylation of the conserved C-terminal domain of ribosomal P-proteins impairs the mode of interaction with plant toxins. | Phosphorylation of the conserved C-terminal domain of ribosomal P-proteins impairs the mode of interaction with plant toxins. Horbowicz-Drożdżal P, Kamel K, Kmiecik S, Borkiewicz L, Tumer NE, Shaw PC, Tchórzewski M, Grela P. | 10/2/2021 |
60S acidic ribosomal protein P1 (RPLP1) is elevated in human endometriotic tissue and in a murine model of endometriosis and is essential for endometriotic epithelial cell survival in vitro. | 60S acidic ribosomal protein P1 (RPLP1) is elevated in human endometriotic tissue and in a murine model of endometriosis and is essential for endometriotic epithelial cell survival in vitro. Alali Z, Graham A, Swan K, Flyckt R, Falcone T, Cui W, Yang X, Christianson J, Nothnick WB., Free PMC Article | 01/30/2021 |
CNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression. | CNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression. Xia L, Yue Y, Li M, Zhang YN, Zhao L, Lu W, Wang X, Xie X., Free PMC Article | 11/21/2020 |
Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins. | Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins. Campos RK, Wijeratne HRS, Shah P, Garcia-Blanco MA, Bradrick SS., Free PMC Article | 11/21/2020 |
absence of RPLP0, RPLP1, or RPLP2 resulted in reactive oxygen species (ROS) accumulation and MAPK1/ERK2 signaling pathway activation. | Disruption of the ribosomal P complex leads to stress-induced autophagy. Artero-Castro A, Perez-Alea M, Feliciano A, Leal JA, Genestar M, Castellvi J, Peg V, Ramón Y Cajal S, Lleonart ME., Free PMC Article | 06/28/2016 |
Evaluated autoantibodies against native ribosomal P complex and recombinant ribosomal P proteins (anti-Rib-P0, anti-Rib-P1, anti-Rib-P2) for prevalence, diagnostic relevance&clinical associations in a Chinese cohort with systemic lupus erythematosus. | Significance of antibodies against the native ribosomal P protein complex and recombinant P0, P1, and P2 proteins in the diagnosis of Chinese patients with systemic lupus erythematosus. Li J, Shen Y, He J, Jia R, Wang X, Chen X, Wang D, Han L, Zhu L, Chi X, Saschenbrecker S, Dähnrich C, Stöcker W, Schlumberger W, Li ZG., Free PMC Article | 11/23/2013 |
Data show that ricin A-chain (RTA) interacts directly with recombinant P1-P2 dimer, indicating the importance of P1 and P2 in enabling RTA to bind and depurinate ribosomes. | The P1/P2 proteins of the human ribosomal stalk are required for ribosome binding and depurination by ricin in human cells. May KL, Li XP, Martínez-Azorín F, Ballesta JP, Grela P, Tchórzewski M, Tumer NE., Free PMC Article | 01/12/2013 |
P proteins are up-regulated in a considerable number of patients with the most common types of cancer. | Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors. Artero-Castro A, Castellvi J, García A, Hernández J, Ramón y Cajal S, Lleonart ME. | 02/26/2011 |
These results support the hypothesis that at least some of the changes in the profile of newly synthesized proteins detected in cells deprived of P1 and P2 proteins might be due to an effect on the efficiency of cap-independent translation. | Internal translation initiation on the foot-and-mouth disease virus IRES is affected by ribosomal stalk conformation. Martínez-Azorín F, Remacha M, Martínez-Salas E, Ballesta JP. | 01/21/2010 |
Data indicate that P1/P2 proteins modulate cytoplasmic translation by influencing the interaction between subunits, thereby regulating the rate of cell proliferation. | Functional characterization of ribosomal P1/P2 proteins in human cells. Martinez-Azorin F, Remacha M, Ballesta JP. | 01/21/2010 |
the P1 and P2 proteins are not actively transported into the nucleus compartment, remaining predominantly in the cytoplasm (the perinuclear compartment). | The subcellular distribution of the human ribosomal "stalk" components: P1, P2 and P0 proteins. Tchórzewski M, Krokowski D, Rzeski W, Issinger OG, Grankowski N. | 01/21/2010 |