| TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux. | TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux.
Zhao D, Qiang L, Lei Z, Ge P, Lu Z, Wang Y, Zhang X, Qiang Y, Li B, Pang Y, Zhang L, Liu CH, Wang J., | 06/28/2024 |
| METTL14 promotes IL-6-induced viability, glycolysis and inflammation in HaCaT cells via the m6A modification of TRIM27. | METTL14 promotes IL-6-induced viability, glycolysis and inflammation in HaCaT cells via the m6A modification of TRIM27.
Chen Y, Xiang Y, Miao X, Kuai L, Ding X, Ma T, Li B, Fan B., Free PMC Article | 02/9/2024 |
| TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma. | TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma.
Kimura S, Suzuki M, Nakamaru Y, Kano S, Watanabe M, Honma A, Nakazono A, Tsushima N, Hatakeyama S, Homma A. | 06/22/2023 |
| CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment. | CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.
Smits DJ, Dekker J, Schot R, Tabarki B, Alhashem A, Demmers JAA, Dekkers DHW, Romito A, van der Spek PJ, van Ham TJ, Bertoli-Avella AM, Mancini GMS., Free PMC Article | 02/27/2023 |
| TRIM27-USP7 complex promotes tumour progression via STAT3 activation in human hepatocellular carcinoma. | TRIM27-USP7 complex promotes tumour progression via STAT3 activation in human hepatocellular carcinoma.
Sakamoto T, Kuboki S, Furukawa K, Takayashiki T, Takano S, Yoshizumi A, Ohtsuka M. | 01/11/2023 |
| Analysis of TRIM27 prognosis value and immune infiltrates in hepatocellular carcinoma. | Analysis of TRIM27 prognosis value and immune infiltrates in hepatocellular carcinoma.
Wang H, Zhang Y, Yan L, Lv Q, Lu J, Yun B., Free PMC Article | 10/15/2022 |
| TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. | TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis.
Yang Y, Zhu Y, Zhou S, Tang P, Xu R, Zhang Y, Wei D, Wen J, Thorne RF, Zhang XD, Guan JL, Liu L, Wu M, Chen S., Free PMC Article | 07/30/2022 |
| TRIM27 regulates the expression of PDCD4 by the ubiquitinproteasome pathway in ovarian and endometrial cancer cells. | TRIM27 regulates the expression of PDCD4 by the ubiquitin‑proteasome pathway in ovarian and endometrial cancer cells.
Yu H, Wan L, Tang Z, Yao C, Zhang D, Jiang M, Wang C, Liu Y, Xue C, Wang X, Shi Y, Zhang L, Wang X, Wei Z. | 05/28/2022 |
| Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC. | Epigenome-wide three-way interaction study identifies a complex pattern between TRIM27, KIAA0226, and smoking associated with overall survival of early-stage NSCLC.
Ji X, Lin L, Fan J, Li Y, Wei Y, Shen S, Su L, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Zhang R, Chen F, Christiani DC., Free PMC Article | 04/23/2022 |
| TRIM27 interacts with Ikappabalpha to promote the growth of human renal cancer cells through regulating the NF-kappaB pathway. | TRIM27 interacts with Iκbα to promote the growth of human renal cancer cells through regulating the NF-κB pathway.
Xiao C, Zhang W, Hua M, Chen H, Yang B, Wang Y, Yang Q., Free PMC Article | 11/6/2021 |
| [Mechanism of TRIM27 promoting inflammatory response in lung cancer cells]. | [Mechanism of TRIM27 promoting inflammatory response in lung cancer cells].
Chen EJ, Chen S, Zhou FL. | 10/30/2021 |
| Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients. | Epigenetic-smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early-stage NSCLC patients.
Ji X, Lin L, Shen S, Dong X, Chen C, Li Y, Zhu Y, Huang H, Chen J, Chen X, Wei L, He J, Duan W, Su L, Jiang Y, Fan J, Guan J, You D, Shafer A, Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Wei Y, Zhang R, Chen F, Christiani DC., Free PMC Article | 09/4/2021 |
| TRIM27-mediated ubiquitination of PPARgamma promotes glutamate-induced cell apoptosis and inflammation. | TRIM27-mediated ubiquitination of PPARγ promotes glutamate-induced cell apoptosis and inflammation.
Hao Y, Bai S, Peng J, Hong R, Ding J, Li Z, Guan Y. | 09/4/2021 |
| TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway. | TRIM27 contributes to glomerular endothelial cell injury in lupus nephritis by mediating the FoxO1 signaling pathway.
Liu J, Xu J, Huang J, Gu C, Liu Q, Zhang W, Gao F, Tian Y, Miao X, Zhu Z, Jia B, Tian Y, Wu L, Zhao H, Feng X, Liu S., Free PMC Article | 09/4/2021 |
| Tripartite Motif-Containing 27 Attenuates Liver Ischemia/Reperfusion Injury by Suppressing Transforming Growth Factor beta-Activated Kinase 1 (TAK1) by TAK1 Binding Protein 2/3 Degradation. | Tripartite Motif-Containing 27 Attenuates Liver Ischemia/Reperfusion Injury by Suppressing Transforming Growth Factor β-Activated Kinase 1 (TAK1) by TAK1 Binding Protein 2/3 Degradation.
Chen SY, Zhang HP, Li J, Shi JH, Tang HW, Zhang Y, Zhang JK, Wen PH, Wang ZH, Shi XY, He YT, Hu BW, Yang H, Guo WZ, Zhang SJ., Free PMC Article | 08/14/2021 |
| Tri-domain proteins 27 reduce inflammation and apoptosis in HK-2 cells and protect against acute kidney injury in mice. | Tri-domain proteins 27 reduce inflammation and apoptosis in HK-2 cells and protect against acute kidney injury in mice.
Li XK, Xu XZ, Cong Q, Zhao F, Yang YY, Li AQ, Ma J. | 07/3/2021 |
| Downregulation of TRIM27 suppresses gastric cancer cell proliferation via inhibition of the Hippo-BIRC5 pathway. | Downregulation of TRIM27 suppresses gastric cancer cell proliferation via inhibition of the Hippo-BIRC5 pathway.
Yao Y, Liu Z, Cao Y, Guo H, Jiang B, Deng J, Xiong J. | 07/3/2021 |
| TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-beta-catenin signaling. | TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling.
Liu S, Tian Y, Zheng Y, Cheng Y, Zhang D, Jiang J, Li S., Free PMC Article | 05/22/2021 |
| TRIM27 expression is significantly increased by IL-6 and suggest a TRIM27/STAT3-dependent mechanism. | TRIM27 promotes IL-6-induced proliferation and inflammation factor production by activating STAT3 signaling in HaCaT cells.
Miao X, Xiang Y, Mao W, Chen Y, Li Q, Fan B. | 05/9/2020 |
| The study suggests that RFP contributes to chemoresistance in glioblastoma via aberrant deacetylation of histone H3 at K27. | Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma.
Ranjit M, Hirano M, Aoki K, Okuno Y, Ohka F, Yamamichi A, Kato A, Maeda S, Motomura K, Matsuo K, Enomoto A, Ino Y, Todo T, Takahashi M, Wakabayashi T, Kato T, Natsume A. | 04/18/2020 |
| Tumor-type-specific NCOA4-RET or TRIM27-RET translocations are found in a subset of widely invasive salivary carcinomas with intercalated duct-like immunoprofiles. | NCOA4-RET and TRIM27-RET Are Characteristic Gene Fusions in Salivary Intraductal Carcinoma, Including Invasive and Metastatic Tumors: Is "Intraductal" Correct?
Skálová A, Ptáková N, Santana T, Agaimy A, Ihrler S, Uro-Coste E, Thompson LDR, Bishop JA, Baněčkova M, Rupp NJ, Morbini P, de Sanctis S, Schiavo-Lena M, Vanecek T, Michal M, Leivo I. | 04/11/2020 |
| NCOA4-RET as the dominant fusion in intercalated duct type salivary gland intraductal carcinoma. A subset of IC patients with apocrine variant IC harbor a novel TRIM27-RET. | Molecular Profiling of Salivary Gland Intraductal Carcinoma Revealed a Subset of Tumors Harboring NCOA4-RET and Novel TRIM27-RET Fusions: A Report of 17 cases.
Skálová A, Vanecek T, Uro-Coste E, Bishop JA, Weinreb I, Thompson LDR, de Sanctis S, Schiavo-Lena M, Laco J, Badoual C, Santana Conceiçao T, Ptáková N, Baněčkova M, Miesbauerová M, Michal M. | 09/7/2019 |
| The roles of Trim27 in hematopoiesis were studied by enforcing its expression in human hematopoietic stem and progenitor cells. Trim27 up-regulated essential regulators of myelopoiesis. The myeloproliferative advantage caused by overexpressing Trim27/TRIM27 is conserved between mouse and human hematopoiesis. | Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes.
Wang T, Xia C, Dong Y, Chen X, Wang J, Du J. | 05/25/2019 |
| findings suggest that USP7 acts as a negative regulator in antiviral signaling by stabilizing TRIM27 and promoting the degradation of TBK1. | USP7-TRIM27 axis negatively modulates antiviral type I IFN signaling.
Cai J, Chen HY, Peng SJ, Meng JL, Wang Y, Zhou Y, Qian XP, Sun XY, Pang XW, Zhang Y, Zhang J. | 04/6/2019 |
| Results showed that TRIM27 was upregulated in colorectal cancer (CRC) tissues, and significantly associated with tumor invasion, metastasis and prognosis. Following TRIM27 inhibition and overexpression in CRC cells, it was found that TRIM27 promoted cell proliferation, possibly via the inhibition of apoptosis and cell cycle regulation. These results suggested that TRIM27 is an oncogenic protein in the progression of CRC. | TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer.
Zhang Y, Feng Y, Ji D, Wang Q, Qian W, Wang S, Zhang Z, Ji B, Zhang C, Sun Y, Fu Z., Free PMC Article | 11/3/2018 |