| A De Novo Noncoding RARB Variant Associated with Complex Microphthalmia Alters a Putative Regulatory Element. | A De Novo Noncoding RARB Variant Associated with Complex Microphthalmia Alters a Putative Regulatory Element.
Replogle MR, Thompson S, Reis LM, Semina EV., Free PMC Article | 11/5/2024 |
| RARB associated with MSI, affects progression and prognosis of gastric cancer. | RARB associated with MSI, affects progression and prognosis of gastric cancer.
Cai X, Lin W, Wu F, Song G, Qian Z, Wang Y., Free PMC Article | 08/26/2024 |
| Promoter hypermethylation of RARB and GSTP1 genes in plasma cell-free DNA as breast cancer biomarkers in Peruvian women. | Promoter hypermethylation of RARB and GSTP1 genes in plasma cell-free DNA as breast cancer biomarkers in Peruvian women.
Danos P, Giannoni-Luza S, Murillo Carrasco AG, Acosta O, Guevara-Fujita ML, Cotrina Concha JM, Guerra Miller H, Pinto Oblitas J, Aguilar Cartagena A, Araujo JM, Fujita R, Buleje Sono JL., Free PMC Article | 12/22/2023 |
| Retinoic Acid Receptor beta Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease. | Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease.
Melis M, Trasino SE, Tang XH, Rappa A, Zhang T, Qin L, Gudas LJ., Free PMC Article | 08/19/2023 |
| Clinical and functional heterogeneity associated with the disruption of retinoic acid receptor beta. | Clinical and functional heterogeneity associated with the disruption of retinoic acid receptor beta.
Caron V, Chassaing N, Ragge N, Boschann F, Ngu AM, Meloche E, Chorfi S, Lakhani SA, Ji W, Steiner L, Marcadier J, Jansen PR, van de Pol LA, van Hagen JM, Russi AS, Le Guyader G, Nordenskjöld M, Nordgren A, Anderlid BM, Plaisancié J, Stoltenburg C, Horn D, Drenckhahn A, Hamdan FF, Lefebvre M, Attie-Bitach T, Forey P, Smirnov V, Ernould F, Jacquemont ML, Grotto S, Alcantud A, Coret A, Ferrer-Avargues R, Srivastava S, Vincent-Delorme C, Romoser S, Safina N, Saade D, Lupski JR, Calame DG, Geneviève D, Chatron N, Schluth-Bolard C, Myers KA, Dobyns WB, Calvas P, DDD Study, Salmon C, Holt R, Elmslie F, Allaire M, Prigozhin DM, Tremblay A, Michaud JL., Free PMC Article | 08/10/2023 |
| Hepatocyte Nuclear Factor 4alpha (HNF4alpha) Plays a Controlling Role in Expression of the Retinoic Acid Receptor beta (RARbeta) Gene in Hepatocytes. | Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes.
Zolfaghari R, Bonzo JA, Gonzalez FJ, Ross AC., Free PMC Article | 05/31/2023 |
| Epigenetic regulation of RARB overcomes the radio-resistance of colorectal carcinoma cells via cancer stem cells. | Epigenetic regulation of RARB overcomes the radio-resistance of colorectal carcinoma cells via cancer stem cells.
Shu Y, Lan J, Hu Z, Liu W, Song R., Free PMC Article | 01/28/2023 |
| DNA hypermethylation of CADM1, PAX5, WT1, RARbeta, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus. | DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus.
Birknerová N, Kovaříková H, Baranová I, Přikrylová A, Laco J, Vošmiková H, Gajdošová B, Hodek M, Vošmik M, Palička V, Chmelařová M., Free PMC Article | 10/29/2022 |
| Aberrant epigenetic regulation of RARbeta by TET2 is involved in cutaneous squamous cell carcinoma resistance to retinoic acid. | Aberrant epigenetic regulation of RARβ by TET2 is involved in cutaneous squamous cell carcinoma resistance to retinoic acid.
Zhang X, Cong Y, Chu Z, Shi L, Zheng Y, Zhao Q, Geng S, Guo K. | 05/7/2022 |
| Polymorphisms in Vitamin A-Related Genes and Their Functions in Autoimmune Thyroid Disease. | Polymorphisms in Vitamin A-Related Genes and Their Functions in Autoimmune Thyroid Disease.
Homma H, Watanabe M, Inoue N, Isono M, Hidaka Y, Iwatani Y. | 03/19/2022 |
| MiR-141-3p and miR-200a-3p are involved in Th17 cell differentiation by negatively regulating RARB expression. | MiR-141-3p and miR-200a-3p are involved in Th17 cell differentiation by negatively regulating RARB expression.
Bahmani L, Baghi M, Peymani M, Javeri A, Ghaedi K. | 01/1/2022 |
| DNA methylation patterns of RAR-beta2 and RASSF1A gene promoters in FNAB samples from Greek population with benign or malignant breast lesions. | DNA methylation patterns of RAR-β2 and RASSF1A gene promoters in FNAB samples from Greek population with benign or malignant breast lesions.
Kougioumtsidou N, Vavoulidis E, Nasioutziki M, Symeonidou M, Pratilas GC, Mareti E, Petousis S, Chatzikyriakidou A, Grimbizis G, Theodoridis T, Miliaras D, Dinas K, Zepiridis L. | 09/11/2021 |
| High-throughput custom capture sequencing identifies novel mutations in coloboma-associated genes: Mutation in DNA-binding domain of retinoic acid receptor beta affects nuclear localization causing ocular coloboma. | High-throughput custom capture sequencing identifies novel mutations in coloboma-associated genes: Mutation in DNA-binding domain of retinoic acid receptor beta affects nuclear localization causing ocular coloboma.
Kalaskar VK, Alur RP, Li LK, Thomas JW, Sergeev YV, Blain D, Hufnagel RB, Cogliati T, Brooks BP., Free PMC Article | 07/24/2021 |
| Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death. | Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death.
Yago-Ibáñez J, García-Pastor C, Lucio-Cazaña FJ, Fernández-Martínez AB. | 01/9/2021 |
| Protein Kinase C Alpha (PKCalpha) overexpression leads to a better response to retinoid acid therapy through Retinoic Acid Receptor Beta (RARbeta) activation in mammary cancer cells. | Protein Kinase C Alpha (PKCα) overexpression leads to a better response to retinoid acid therapy through Retinoic Acid Receptor Beta (RARβ) activation in mammary cancer cells.
Bessone MID, Berardi DE, Cirigliano SM, Delbart DI, Peters MG, Todaro LB, Urtreger AJ. | 12/5/2020 |
| By using two longitudinal cohort studies, we consistently found that rs1529672 in RARB could significantly modify and enhance the effect of polycyclic aromatic hydrocarbon (PAH) exposure on increased annual FEV1/FVC decline. Specifically, PAH exposure may lead to RARB hypermethylation, and the rs1529672-A allele was associated with decreased RARB mRNA expression. mRNA expression. | Interaction of RARB Variant with Polycyclic Aromatic Hydrocarbon Exposure on Annual Lung Function Change.
Wu X, Yang S, Bai Y, Li G, Wei W, He M, Zhang X, Wu T, Chen W, Guo H. | 07/4/2020 |
| expression significantly reduced in cirrhotic and hepatocellular carcinoma tissues | Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells.
Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, Thorpe S, Lee DA, Possamai LA, Wang H, Pinato DJ, Del Río Hernández AE. | 05/23/2020 |
| our results defined NR1B2 as a tumor suppressor in KIRC that restricted EMT by the LATS1/2-YAP pathway. | NR1B2 suppress kidney renal clear cell carcinoma (KIRC) progression by regulation of LATS 1/2-YAP signaling.
Yin L, Li W, Wang G, Shi H, Wang K, Yang H, Peng B., Free PMC Article | 01/18/2020 |
| A genetic variant of the RARB gene was associated with carotid intima-media thickness (CIMT) at the genome-wide level of significance. The present findings strongly suggest that genetic variation within RARB contributes to the development of subclinical atherosclerosis in patients with Rheumatoid Arthritis. | Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study.
López-Mejías R, Carmona FD, Genre F, Remuzgo-Martínez S, González-Juanatey C, Corrales A, Vicente EF, Pulito-Cueto V, Miranda-Filloy JA, Ramírez Huaranga MA, Blanco R, Robustillo-Villarino M, Rodríguez-Carrio J, Alperi-López M, Alegre-Sancho JJ, Mijares V, Lera-Gómez L, Pérez-Pampín E, González A, Ortega-Castro R, López-Pedrera C, García Vivar ML, Gómez-Arango C, Raya E, Narvaez J, Balsa A, López-Longo FJ, Carreira P, González-Álvaro I, Rodríguez-Rodríguez L, Fernández-Gutiérrez B, Ferraz-Amaro I, Gualillo O, Castañeda S, Martín J, Llorca J, González-Gay MA., Free PMC Article | 12/7/2019 |
| Results from this study revealed a novel anticancer mechanism of RARbeta via miR-22 induction to epigenetically regulate itself and NUR77, providing a promising cancer treatment modality using miR-22 and its inducers | RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.
Hu Y, French SW, Chau T, Liu HX, Sheng L, Wei F, Stondell J, Garcia JC, Du Y, Bowlus CL, Wan YY., Free PMC Article | 10/5/2019 |
| Our results demonstrate that the majority of RARA-negative acute promyelocytic leukemia (APL) have RARB translocations, thereby forming a novel, distinct subgroup of APL. TBL1XR1-RARB as an oncogenic protein exerts effects similar to those of PML-RARA, underpinning the importance of retinoic acid pathway alterations in the pathogenesis of APL. | Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.
Osumi T, Tsujimoto SI, Tamura M, Uchiyama M, Nakabayashi K, Okamura K, Yoshida M, Tomizawa D, Watanabe A, Takahashi H, Hori T, Yamamoto S, Hamamoto K, Migita M, Ogata-Kawata H, Uchiyama T, Kizawa H, Ueno-Yokohata H, Shirai R, Seki M, Ohki K, Takita J, Inukai T, Ogawa S, Kitamura T, Matsumoto K, Hata K, Kiyokawa N, Goyama S, Kato M. | 09/28/2019 |
| Hypermethylation-induced RARbeta down-expression was associated with LS-VSCC and correlates with the upregulation of c-Jun. The degree of methylation of RARbeta promoter increased with the malignancy of LS-VSCC. Therefore, RARbeta gene dysregulation may play a role in progression of LS-VSCC. | Association of Retinoic Acid Receptor β Gene With Onset and Progression of Lichen Sclerosus-Associated Vulvar Squamous Cell Carcinoma.
Rotondo JC, Borghi A, Selvatici R, Mazzoni E, Bononi I, Corazza M, Kussini J, Montinari E, Gafà R, Tognon M, Martini F., Free PMC Article | 09/21/2019 |
| Data provide a strong evidence for association involving RARB methylation on prostate cancer risk. [review] | Gene promoter methylation and cancer: An umbrella review.
Bouras E, Karakioulaki M, Bougioukas KI, Aivaliotis M, Tzimagiorgis G, Chourdakis M. | 07/27/2019 |
| High expression of RARbeta was associated with overall survival in colorectal cancer patients. | High Expression of RARβ Is a Favorable Factor in Colorectal Cancer.
Wang W, Liu S, Jiang C, Wang Y, Zhu H, Wang X., Free PMC Article | 07/20/2019 |
| High expression of RARB is associated with high grade of Cervical Pre-Neoplastic Lesions. | Risk Categorization with Different Grades of Cervical Pre-Neoplastic Lesions - High Risk HPV Associations and Expression of p53 and RARβ.
Ghosh D, Roy AK, Murmu N, Mandal S, Roy A., Free PMC Article | 07/13/2019 |